ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Contusion of ankle (finn-b-ST19_CONTU_ANKLE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Orange (ukb-b-13520) (👉 📊) Contusion of ankle Inverse variance weighted 7 -3.475258229 1.439224437 0.015749287
Rose wine (ukb-b-16124) (👉 📊) Contusion of ankle Inverse variance weighted 14 2.477407196 1.092049524 0.023293573
Cheesecake (ukb-b-1814) (👉 📊) Contusion of ankle MR Egger 26 -6.977923759 3.293433041 0.044655903
Grapefruit (ukb-b-18758) (👉 📊) Contusion of ankle Inverse variance weighted 16 -5.703759141 2.346991937 0.015088731
Mixed fruit (ukb-b-18956) (👉 📊) Contusion of ankle Inverse variance weighted 16 -1.645290072 0.811955148 0.042730853
Mixed fruit (ukb-b-18956) (👉 📊) Contusion of ankle Simple mode 16 -6.225652912 2.615397059 0.030989299
Low calorie drink (ukb-b-19703) (👉 📊) Contusion of ankle Inverse variance weighted 19 1.065731896 0.541461767 0.049039328
Cheesy biscuits (ukb-b-19847) (👉 📊) Contusion of ankle Simple mode 24 12.32109373 4.760957079 0.016447441
Salad / raw vegetable (ukb-b-1996) (👉 📊) Contusion of ankle Weighted median 109 -2.855965445 1.259185227 0.023322753
Salad / raw vegetable (ukb-b-1996) (👉 📊) Contusion of ankle Inverse variance weighted 109 -1.862231797 0.881141152 0.03456382
Goat's cheese (ukb-b-20122) (👉 📊) Contusion of ankle Inverse variance weighted 35 -3.923612957 1.59597269 0.013953969
Beef (ukb-b-2862) (👉 📊) Contusion of ankle MR Egger 98 6.12995985 2.424823835 0.013103364
White wine (ukb-b-311) (👉 📊) Contusion of ankle Inverse variance weighted 13 -1.380652138 0.699477089 0.048400544
Croissant (ukb-b-4007) (👉 📊) Contusion of ankle MR Egger 27 5.064124658 1.788171072 0.00900577
Croissant (ukb-b-4007) (👉 📊) Contusion of ankle Inverse variance weighted 27 2.550568314 1.176588105 0.030176455
Croissant (ukb-b-4007) (👉 📊) Contusion of ankle Weighted mode 27 4.021899102 1.900545273 0.044061954
Dairy smoothie (ukb-b-4955) (👉 📊) Contusion of ankle MR Egger 18 4.068525428 1.83337094 0.041282289
Sausage (ukb-b-5847) (👉 📊) Contusion of ankle Inverse variance weighted 12 -2.079761408 0.889672339 0.019404311
Watercress (ukb-b-6181) (👉 📊) Contusion of ankle Inverse variance weighted 12 3.897074662 1.457515791 0.007500193
Squash (ukb-b-8793) (👉 📊) Contusion of ankle MR Egger 18 -4.185365246 1.795616503 0.03316548
Chocolate biscuits (ukb-b-9886) (👉 📊) Contusion of ankle MR Egger 8 -3.128757842 1.241778454 0.045312911

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Orange (ukb-b-13520) Contusion of ankle rs4782961 -8.76797640021305 3.46504808339528 0.0113930801386303
Orange (ukb-b-13520) Contusion of ankle All - Inverse variance weighted -3.47525822886223 1.43922443725397 0.0157492865704652
Rose wine (ukb-b-16124) Contusion of ankle rs591596 12.0735226485943 5.98875024637264 0.043796446194597
Rose wine (ukb-b-16124) Contusion of ankle All - Inverse variance weighted 2.47740719555064 1.09204952356227 0.0232935731277316
Cheesecake (ukb-b-1814) Contusion of ankle rs73084384 -24.7983215834758 11.7227787118012 0.0343961930904851
Cheesecake (ukb-b-1814) Contusion of ankle All - MR Egger -6.97792375880132 3.29343304108375 0.0446559028754948
Grapefruit (ukb-b-18758) Contusion of ankle rs149410520 -14.0521086651133 4.97616955899891 0.0047446056825947
Grapefruit (ukb-b-18758) Contusion of ankle All - Inverse variance weighted -5.70375914068462 2.34699193671138 0.0150887308286812
Mixed fruit (ukb-b-18956) Contusion of ankle All - Inverse variance weighted -1.64529007180417 0.811955148178525 0.0427308532884421
Low calorie drink (ukb-b-19703) Contusion of ankle All - Inverse variance weighted 1.06573189603681 0.541461767007347 0.0490393280245601
Cheesy biscuits (ukb-b-19847) Contusion of ankle rs145326237 19.1842019150056 7.97017940728727 0.0160842799293457
Salad / raw vegetable (ukb-b-1996) Contusion of ankle rs1004549 -15.1341435450585 7.13302977691879 0.0338630061654292
Salad / raw vegetable (ukb-b-1996) Contusion of ankle rs2447090 18.5190527806742 9.16335920230691 0.0432808514981676
Salad / raw vegetable (ukb-b-1996) Contusion of ankle rs72866712 25.5713590668697 12.2201651681063 0.0363889604681277
Salad / raw vegetable (ukb-b-1996) Contusion of ankle All - Inverse variance weighted -1.86223179699549 0.881141152071938 0.0345638201725713
Goat's cheese (ukb-b-20122) Contusion of ankle All - Inverse variance weighted -3.92361295654108 1.59597269024098 0.0139539691769743
Beef (ukb-b-2862) Contusion of ankle rs12257513 -16.338766786422 7.65036284726367 0.0327050807030605
Beef (ukb-b-2862) Contusion of ankle rs140748046 19.7515410146989 9.67662399241347 0.0412348934300716
Beef (ukb-b-2862) Contusion of ankle rs2403202 17.4962115145989 7.64778361347971 0.0221521256136835
Beef (ukb-b-2862) Contusion of ankle rs4714375 -21.4291629467198 7.87286346480864 0.0064907384094095
Beef (ukb-b-2862) Contusion of ankle rs7791463 -16.4948064923558 6.93305517329496 0.0173524211371577
Beef (ukb-b-2862) Contusion of ankle rs80321956 20.4069291200062 9.6372162573736 0.0342163471492523
Beef (ukb-b-2862) Contusion of ankle rs952645 -18.6254494004421 8.37325551922381 0.0261217058427895
Beef (ukb-b-2862) Contusion of ankle All - MR Egger 6.12995985023334 2.42482383469036 0.013103364216957
White wine (ukb-b-311) Contusion of ankle All - Inverse variance weighted -1.38065213764412 0.699477088599897 0.0484005436976214
Croissant (ukb-b-4007) Contusion of ankle rs145083515 -13.7201499742533 6.29586122554068 0.0293143467666792
Croissant (ukb-b-4007) Contusion of ankle rs76127800 10.1940735363396 5.10475955115185 0.0458279769084771
Croissant (ukb-b-4007) Contusion of ankle All - Inverse variance weighted 2.55056831423613 1.17658810470414 0.0301764545315811
Croissant (ukb-b-4007) Contusion of ankle All - MR Egger 5.06412465774732 1.78817107185782 0.0090057699674005
Dairy smoothie (ukb-b-4955) Contusion of ankle rs9940345 -14.8344256958052 6.21018814843025 0.0169069966186577
Dairy smoothie (ukb-b-4955) Contusion of ankle All - MR Egger 4.06852542762253 1.83337093963585 0.0412822892881861
Sausage (ukb-b-5847) Contusion of ankle All - Inverse variance weighted -2.07976140847966 0.889672338915197 0.0194043110313484
Watercress (ukb-b-6181) Contusion of ankle rs187693683 11.0876995511386 4.72368258500226 0.0189121776345942
Watercress (ukb-b-6181) Contusion of ankle All - Inverse variance weighted 3.89707466159131 1.45751579087447 0.007500192897075
Squash (ukb-b-8793) Contusion of ankle rs117062976 -6.76469117684816 2.44318051293278 0.0056262244183954
Squash (ukb-b-8793) Contusion of ankle rs12562325 -6.31616619351843 3.06861213613128 0.0395600363631376
Squash (ukb-b-8793) Contusion of ankle All - MR Egger -4.18536524604658 1.79561650267192 0.0331654797795516
Chocolate biscuits (ukb-b-9886) Contusion of ankle rs12908565 4.30570505920344 2.12401968322313 0.0426471441590264
Chocolate biscuits (ukb-b-9886) Contusion of ankle All - MR Egger -3.12875784215538 1.24177845422468 0.0453129107177107