ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Weighted median 12 -0.968094608 0.348766226 0.005507126
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 12 -0.654949599 0.260174843 0.01182433
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Simple mode 12 -1.090341297 0.489975231 0.04791905
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Weighted mode 12 -1.03336918 0.451496694 0.042870768
Herbal tea (ukb-b-13344) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 121 0.011070505 0.005562796 0.048872775
Lobster/crab (ukb-b-14746) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 54 -1.898601349 0.87935435 0.030843524
Cereal (ukb-b-15926) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 175 -0.466746434 0.169007884 0.005750404
Cereal bar (ukb-b-18788) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 12 0.684694082 0.322428021 0.033707256
Mixed fruit (ukb-b-18956) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Simple mode 16 -1.478750854 0.66292939 0.041398163
Bran cereal (ukb-b-19498) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Weighted median 4 1.274003971 0.645847695 0.048540304
Salad / raw vegetable (ukb-b-1996) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 109 1.915299046 0.912839981 0.038243832
Salad / raw vegetable (ukb-b-1996) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 109 0.592590023 0.291878201 0.042329635
Lettuce (ukb-b-2867) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 12 -0.936393283 0.387287026 0.036195788
Porridge (ukb-b-29) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 14 2.034984933 0.660436457 0.009515383
Standard tea (ukb-b-3291) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Weighted median 14 0.003224371 0.00163155 0.048125064
Standard tea (ukb-b-3291) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 14 0.003215031 0.001170549 0.00602164
Drinking water (ukb-b-3975) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 24 -0.132790178 0.066639377 0.046297774
Danish pastry (ukb-b-447) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 16 -6.675278102 2.584397212 0.021686171
Coffee (ukb-b-5237) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 117 0.501976229 0.199350966 0.011800568
Stewed fruit (ukb-b-8676) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle MR Egger 9 -3.418826007 1.20404549 0.025064384
Squash (ukb-b-8793) (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle Inverse variance weighted 18 -0.574455776 0.232909815 0.013646736

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Chocolate bar (ukb-b-117) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted -0.654949599014237 0.260174843460316 0.0118243296006787
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs117871743 0.0568234770961978 0.0253229272345287 0.0248353783654784
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs142924308 0.0616215992666065 0.0278468972077282 0.0269065207583642
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs146023233 0.151522737798696 0.0754171412835309 0.0445234940379067
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs17658212 0.140356586226386 0.0590884957267885 0.0175317315861892
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs186275605 0.0682615230460922 0.0307968878934339 0.0266567869019391
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs74024145 -0.109180214440465 0.0363057098621304 0.0026362600462569
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs76771047 0.0686508382562937 0.0279765696229408 0.0141328437617203
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs78323836 0.0506891464988209 0.0246429341520264 0.0396915701375646
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger 0.0110705049897606 0.0055627961611342 0.0488727751724482
Lobster/crab (ukb-b-14746) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs10281272 -17.9292814670237 8.52694579715596 0.0354953612996384
Lobster/crab (ukb-b-14746) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs35976064 -15.1087832393231 7.09553227683767 0.033226344090106
Lobster/crab (ukb-b-14746) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs75589235 -6.33139373787753 3.11027985591577 0.0417870462631175
Lobster/crab (ukb-b-14746) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted -1.89860134871892 0.879354350227879 0.0308435236230971
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs10809287 5.01512626793716 2.25478459223788 0.0261339657288169
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs10931025 -5.51009458995713 2.62212834653662 0.0356074039000458
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs11764446 -5.62311187834785 2.55769084308598 0.027912699713468
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs1397440 -6.29536882159505 2.44939264731002 0.0101647023960557
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs2472297 -3.20468337980545 1.57710796250268 0.0421536559466274
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs3021529 -6.21133547881476 2.89306498140768 0.03179534652626
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs34227840 -5.13954486014428 2.38325668917981 0.0310429481461483
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs6062362 -6.41283499775551 2.75168919903691 0.0197792926408304
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs78854891 -6.78376413096007 2.303408593069 0.003228523444696
Cereal (ukb-b-15926) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted -0.466746434140322 0.169007883530301 0.0057504035310783
Cereal bar (ukb-b-18788) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted 0.684694081514261 0.322428020582507 0.0337072559648372
Bran cereal (ukb-b-19498) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs8176599 1.97150231427359 0.663977463356389 0.0029854629880888
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs1019957 7.11852228375542 3.22558040982668 0.0273212873976749
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs12517711 7.28818525674492 3.37636337404305 0.0308819653086537
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs34186148 -6.68205111644902 3.10504234035735 0.0313973543643118
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs58214669 -10.9850542234482 3.85087178610879 0.0043361133970143
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs71645290 8.53623302602895 3.83473852861608 0.0260123463468513
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs78706681 6.75323685247068 2.63014116361511 0.0102395544673077
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted 0.59259002329737 0.291878200963405 0.0423296350555018
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger 1.91529904560089 0.912839980768984 0.0382438323047683
Lettuce (ukb-b-2867) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs56169733 -1.21881516953734 0.528307716073222 0.0210538420946188
Lettuce (ukb-b-2867) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger -0.936393283039896 0.387287025601553 0.0361957883303006
Porridge (ukb-b-29) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs138894584 1.91322504126343 0.938010155763802 0.0413838565301032
Porridge (ukb-b-29) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs4906184 -3.31782610263623 1.2261531248873 0.0068123175199169
Porridge (ukb-b-29) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs911784 -2.9001767625983 1.16959683309165 0.0131515824031249
Porridge (ukb-b-29) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger 2.03498493261028 0.660436457490466 0.0095153833475
Standard tea (ukb-b-3291) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs10493552 0.0096559346188523 0.0048085778824806 0.0446364363348544
Standard tea (ukb-b-3291) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs2472297 0.0049767327945138 0.0024491795248591 0.0421536559466274
Standard tea (ukb-b-3291) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs908817 0.0089658382486474 0.0043112328599879 0.0375580128435583
Standard tea (ukb-b-3291) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted 0.0032150311181756 0.001170549167691 0.006021640420796
Drinking water (ukb-b-3975) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs2472297 -0.516483762279198 0.25417507986181 0.0421536559466274
Drinking water (ukb-b-3975) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs35294020 -0.462954064302837 0.155965544794787 0.0029944230104997
Drinking water (ukb-b-3975) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted -0.132790178217536 0.0666393770570324 0.0462977741637733
Danish pastry (ukb-b-447) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs12626168 10.5360071703382 4.32293349755196 0.0148000354137517
Danish pastry (ukb-b-447) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs34599940 5.41508929222837 2.73997033049879 0.0481172599267946
Danish pastry (ukb-b-447) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger -6.67527810154954 2.58439721168584 0.0216861712320811
Coffee (ukb-b-5237) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs117810762 6.54439326512312 3.14409361545702 0.0373892574613472
Coffee (ukb-b-5237) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs13088645 -6.9278969768825 2.83824457153473 0.0146503422314068
Coffee (ukb-b-5237) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs2472297 1.09315957547535 0.537972232025272 0.0421536559466274
Coffee (ukb-b-5237) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs6062682 5.31319910514541 2.2467792949163 0.0180394755771661
Coffee (ukb-b-5237) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted 0.501976229429126 0.19935096586093 0.0118005677334798
Stewed fruit (ukb-b-8676) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs150680000 -2.47130737158809 1.13255236687823 0.0291044432368178
Stewed fruit (ukb-b-8676) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs2519958 4.06550931122991 2.03275465561495 0.0455002638963584
Stewed fruit (ukb-b-8676) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - MR Egger -3.41882600668614 1.20404549012737 0.0250643837354074
Squash (ukb-b-8793) Dislocation, sprain and strain of joints and ligaments of shoulder girdle rs9427097 -2.23649521382947 0.891767078932003 0.0121438485606677
Squash (ukb-b-8793) Dislocation, sprain and strain of joints and ligaments of shoulder girdle All - Inverse variance weighted -0.574455776430952 0.232909815169413 0.013646736475218