ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Dislocation, sprain and strain of joints and ligaments of thorax (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_THORAX)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Bread (ukb-b-11348) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted median 113 2.217744957 1.038910731 0.032786922
Bread (ukb-b-11348) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 113 1.537073863 0.711181252 0.030672409
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax MR Egger 12 -5.429585884 1.598584533 0.00681106
Chocolate bar (ukb-b-117) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted median 12 -2.568934122 1.275497892 0.044002836
Naan bread (ukb-b-13281) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted median 18 12.1347027 4.454588454 0.006447881
Naan bread (ukb-b-13281) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 18 11.47365307 3.30331798 0.000513962
Naan bread (ukb-b-13281) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted mode 18 13.8571255 5.591187316 0.023984405
Herbal tea (ukb-b-13344) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 121 -0.022863167 0.009635575 0.017654444
Dried fruit (ukb-b-15321) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted median 7 -5.109712503 2.073760174 0.013740213
Dried fruit (ukb-b-15321) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 7 -4.213950191 1.6141574 0.009037849
Other savoury snack (ukb-b-18718) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 24 4.211343504 2.03935608 0.038919604
Salad / raw vegetable (ukb-b-1996) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax MR Egger 109 8.261952066 3.270466469 0.012993394
Plain cereal (ukb-b-20023) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 13 2.489357161 1.210105377 0.039672683
Beef (ukb-b-2862) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 98 1.955877144 0.905245366 0.030725909
Prune (ukb-b-3022) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax MR Egger 15 -6.977383964 3.159959489 0.045813903
Fresh fruit (ukb-b-3881) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Weighted median 141 -3.120091578 1.509835806 0.0387803
Fresh fruit (ukb-b-3881) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 141 -2.180922627 0.984489627 0.026740681
Apple (ukb-b-4070) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 18 1.3384089 0.672312382 0.046507884
Seeds (ukb-b-4548) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 15 -5.87473915 2.617001596 0.024778669
Beer/cider (ukb-b-4961) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 14 1.926774402 0.735235037 0.008776907
Baguette (ukb-b-5277) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 13 2.918557756 1.138204465 0.010342078
Eggs in sandwiches (ukb-b-5382) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 15 5.961078154 2.800089966 0.033263521
Fresh tomato (ukb-b-730) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 10 1.573492021 0.653296855 0.016016443
Filtered coffee (ukb-b-748) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 21 -1.198345857 0.493199919 0.015109802
Cooked vegetable (ukb-b-8089) (👉 📊) Dislocation, sprain and strain of joints and ligaments of thorax Inverse variance weighted 94 2.551038883 0.99852186 0.010624417

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs116448128 18.9078644332297 8.0947406838747 0.0195005781071381
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs12349638 20.1669791082852 7.57590398701274 0.0077680233309947
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs12510662 19.502520628895 8.69145648999364 0.0248406028305982
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs1566029 19.5758188938564 8.11909965880948 0.0159052513174806
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs4908506 15.9624584930341 7.65649155224618 0.0370850285197915
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs57824799 -12.6427596191404 5.25348231339566 0.0161040685871831
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax rs6090344 18.6344329831061 7.84817807300482 0.0175792017893828
Bread (ukb-b-11348) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 1.53707386296329 0.711181251548535 0.0306724091334316
Chocolate bar (ukb-b-117) Dislocation, sprain and strain of joints and ligaments of thorax All - MR Egger -5.42958588425961 1.59858453339952 0.0068110599057727
Naan bread (ukb-b-13281) Dislocation, sprain and strain of joints and ligaments of thorax rs2231640 16.1196898041514 7.0700393877857 0.0226076884771056
Naan bread (ukb-b-13281) Dislocation, sprain and strain of joints and ligaments of thorax rs76569571 42.6446795809072 14.7686078402533 0.0038828948999404
Naan bread (ukb-b-13281) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 11.4736530698845 3.30331798029439 0.0005139619348536
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs116448040 0.742008422692186 0.353137894588731 0.0356246362795663
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs117462705 -0.18583291804256 0.0825768831301902 0.0244221055883035
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs144818462 -0.404007705912077 0.140696058615462 0.0040853821167424
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs145459923 1.49953445201919 0.633762068266664 0.0179773525719511
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs1796468 -0.10378520681101 0.0526037912338265 0.0485000529474969
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs182602 0.432244322443224 0.209642096420964 0.0392248511394109
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs190981462 -0.211452901497393 0.0920237013142338 0.0215726546357252
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax rs9792589 -0.308705304584749 0.116216488950183 0.0079004416580755
Herbal tea (ukb-b-13344) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted -0.0228631673505387 0.0096355752766463 0.0176544435213184
Dried fruit (ukb-b-15321) Dislocation, sprain and strain of joints and ligaments of thorax rs190615711 -6.65847059743729 2.94015599272382 0.0235331983348072
Dried fruit (ukb-b-15321) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted -4.21395019133684 1.6141574001681 0.0090378486767572
Other savoury snack (ukb-b-18718) Dislocation, sprain and strain of joints and ligaments of thorax rs183277736 22.2082239967725 9.99201983186794 0.0262430495475875
Other savoury snack (ukb-b-18718) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 4.21134350382831 2.03935608001589 0.0389196042843244
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax rs1011530 -34.9472459340347 12.3923677367846 0.004801436441503
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax rs146555011 27.4784595710782 13.8833567430452 0.0477892785171627
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax rs16869875 25.1369350884209 9.46286668173677 0.0078985415146755
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax rs17457620 23.6781139275007 11.2428454619787 0.0351990881882301
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax rs59128343 -26.39103648829 11.1142739031985 0.0175719091965074
Salad / raw vegetable (ukb-b-1996) Dislocation, sprain and strain of joints and ligaments of thorax All - MR Egger 8.26195206550629 3.27046646912454 0.0129933938829221
Plain cereal (ukb-b-20023) Dislocation, sprain and strain of joints and ligaments of thorax rs148151996 6.03601961415498 2.78595465163932 0.0302661819261553
Plain cereal (ukb-b-20023) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 2.48935716127223 1.21010537674744 0.0396726826201841
Beef (ukb-b-2862) Dislocation, sprain and strain of joints and ligaments of thorax rs1421085 12.8596410188729 6.4669394219348 0.046754164215954
Beef (ukb-b-2862) Dislocation, sprain and strain of joints and ligaments of thorax rs62419271 23.4581483870152 11.918762724939 0.0490485082760759
Beef (ukb-b-2862) Dislocation, sprain and strain of joints and ligaments of thorax rs7174015 -27.8046870416029 9.78313062574915 0.0044816691604716
Beef (ukb-b-2862) Dislocation, sprain and strain of joints and ligaments of thorax rs80321956 23.2684071930027 11.2342563730422 0.0383399816167342
Beef (ukb-b-2862) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 1.95587714440532 0.905245366193351 0.0307259092759302
Prune (ukb-b-3022) Dislocation, sprain and strain of joints and ligaments of thorax rs118054480 -15.8790893437918 6.50929718491337 0.014709736142292
Prune (ukb-b-3022) Dislocation, sprain and strain of joints and ligaments of thorax All - MR Egger -6.97738396434052 3.15995948876441 0.045813902781649
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs2425840 -30.7127751065842 12.5636215059819 0.0145021002217221
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs2867113 -18.3686131913481 7.58264432997129 0.0154160432188849
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs4585695 23.6965725759705 12.0105915796015 0.0484986416561005
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs586346 -27.0598263432394 12.5691665342329 0.0313286167053741
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs62334820 -29.9164991561464 14.1664681268733 0.0347051109233171
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs6758494 -23.9613826696964 11.5811473776973 0.0385461778944422
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs7579662 35.7817768401392 13.6359868241854 0.0086886059057543
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs7778914 -25.5481353941698 12.9382843834907 0.0483118118271274
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs7982441 21.9671016501478 10.8765681871673 0.0434174077018779
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax rs9347904 27.8206622766943 13.0438892214626 0.0329370132709539
Fresh fruit (ukb-b-3881) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted -2.18092262739465 0.984489627439506 0.0267406813475161
Apple (ukb-b-4070) Dislocation, sprain and strain of joints and ligaments of thorax rs10938443 7.26076472247803 2.9649896997216 0.0143319867409316
Apple (ukb-b-4070) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 1.33840890047553 0.672312382441421 0.0465078838544828
Seeds (ukb-b-4548) Dislocation, sprain and strain of joints and ligaments of thorax rs6571334 -31.9130951666821 10.3613945346371 0.0020700059496056
Seeds (ukb-b-4548) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted -5.87473914998267 2.61700159615991 0.0247786687727695
Beer/cider (ukb-b-4961) Dislocation, sprain and strain of joints and ligaments of thorax rs6839368 7.2466444564278 3.25274119162117 0.0258900068000359
Beer/cider (ukb-b-4961) Dislocation, sprain and strain of joints and ligaments of thorax rs72863060 6.04770447015485 2.84286433664242 0.0333928525152507
Beer/cider (ukb-b-4961) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 1.92677440185031 0.735235037075928 0.008776906839352
Baguette (ukb-b-5277) Dislocation, sprain and strain of joints and ligaments of thorax rs11642278 9.21283274224451 4.32446020681315 0.033138551968894
Baguette (ukb-b-5277) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 2.918557755959 1.13820446515896 0.0103420777235241
Eggs in sandwiches (ukb-b-5382) Dislocation, sprain and strain of joints and ligaments of thorax rs114267116 20.9082869215432 10.2988211352477 0.0423399605176302
Eggs in sandwiches (ukb-b-5382) Dislocation, sprain and strain of joints and ligaments of thorax rs9879100 28.143019837858 13.909457981283 0.0430421268648649
Eggs in sandwiches (ukb-b-5382) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 5.9610781543682 2.80008996635569 0.033263521151999
Fresh tomato (ukb-b-730) Dislocation, sprain and strain of joints and ligaments of thorax rs76800056 5.19357827611475 2.15712754425382 0.01605617369096
Fresh tomato (ukb-b-730) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 1.57349202112395 0.653296854669148 0.0160164431931938
Filtered coffee (ukb-b-748) Dislocation, sprain and strain of joints and ligaments of thorax rs2830854 -5.33550147965036 2.14077073221477 0.0126909007237142
Filtered coffee (ukb-b-748) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted -1.19834585709136 0.493199918534727 0.0151098023373611
Cooked vegetable (ukb-b-8089) Dislocation, sprain and strain of joints and ligaments of thorax rs13346101 21.8012566907144 9.20642308587387 0.0178821899256285
Cooked vegetable (ukb-b-8089) Dislocation, sprain and strain of joints and ligaments of thorax rs1421085 -15.0896279375895 7.58836966200782 0.046754164215954
Cooked vegetable (ukb-b-8089) Dislocation, sprain and strain of joints and ligaments of thorax rs1444405 22.6290523769325 9.91596003376718 0.0224843895371476
Cooked vegetable (ukb-b-8089) Dislocation, sprain and strain of joints and ligaments of thorax rs1794191 -43.0760748598675 18.0972606516035 0.0173007139322254
Cooked vegetable (ukb-b-8089) Dislocation, sprain and strain of joints and ligaments of thorax All - Inverse variance weighted 2.55103888321107 0.998521860070407 0.0106244170360393