ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweetcorn (ukb-b-13567) (👉 📊) Fracture of foot, except ankle Weighted median 20 -0.994647643 0.469530355 0.03414219
Sweetcorn (ukb-b-13567) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 20 -0.905531809 0.355592275 0.010879511
Lamb/mutton (ukb-b-14179) (👉 📊) Fracture of foot, except ankle MR Egger 128 2.250338406 0.941865466 0.018366134
Shellfish (ukb-b-143) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 40 1.676218001 0.731298906 0.02189926
Canned soup (ukb-b-15094) (👉 📊) Fracture of foot, except ankle Weighted median 10 -1.780218035 0.792925776 0.024760064
Powdered/instant soup (ukb-b-19931) (👉 📊) Fracture of foot, except ankle MR Egger 18 2.995723006 1.363885078 0.04314123
Single crust pastry (ukb-b-2024) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 15 0.983975731 0.463488513 0.033755729
Parsnip (ukb-b-2468) (👉 📊) Fracture of foot, except ankle Weighted median 20 -1.353792001 0.62642214 0.03068378
Fresh fruit (ukb-b-3881) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 141 -0.594497928 0.29963932 0.047250811
Drinking water (ukb-b-3975) (👉 📊) Fracture of foot, except ankle MR Egger 24 0.304216732 0.132835197 0.031964831
Bacon (ukb-b-4414) (👉 📊) Fracture of foot, except ankle MR Egger 12 2.522722774 1.07349964 0.040640725
Pork (ukb-b-5185) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 16 -0.87896958 0.44327583 0.047379121
Baguette (ukb-b-5277) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 13 0.748109308 0.356896859 0.036068898
Couscous (ukb-b-758) (👉 📊) Fracture of foot, except ankle Inverse variance weighted 17 1.927603278 0.923714825 0.036906689
Soya dessert (ukb-b-998) (👉 📊) Fracture of foot, except ankle Weighted median 28 -3.271019139 1.618689801 0.043302342

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweetcorn (ukb-b-13567) Fracture of foot, except ankle rs7647832 -3.34928229665072 1.68831168831169 0.047277508036904
Sweetcorn (ukb-b-13567) Fracture of foot, except ankle All - Inverse variance weighted -0.905531809071543 0.355592274819038 0.0108795113589773
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs10883567 -6.66289747570185 3.37291905408973 0.048221657477716
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs115145470 -12.3689707736605 4.37548224401076 0.0047003685787205
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs11672035 8.15769928528814 3.15460555808293 0.0097106815289304
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs136548 7.70004647303253 2.55968847332416 0.0026280296098295
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs4676964 9.04456186055141 3.1436938660606 0.0040141302836306
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs61836106 -9.42133578270568 4.21641954249224 0.0254541471779501
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs6829572 -6.11831924770861 3.0115462444947 0.0421920843227273
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle rs7199285 7.82516471861829 3.54989916308105 0.0275008378364022
Lamb/mutton (ukb-b-14179) Fracture of foot, except ankle All - MR Egger 2.25033840558278 0.941865466245222 0.018366133954458
Shellfish (ukb-b-143) Fracture of foot, except ankle rs191200892 11.8179356608174 4.66865233607309 0.0113628390670825
Shellfish (ukb-b-143) Fracture of foot, except ankle All - Inverse variance weighted 1.67621800148294 0.731298906346497 0.021899259801071
Canned soup (ukb-b-15094) Fracture of foot, except ankle rs147596965 4.0843622138969 1.75095457585193 0.0196665817438312
Powdered/instant soup (ukb-b-19931) Fracture of foot, except ankle rs6881144 3.99521969346721 1.94090913055994 0.0395491653555028
Powdered/instant soup (ukb-b-19931) Fracture of foot, except ankle All - MR Egger 2.99572300634382 1.36388507759001 0.0431412298893406
Single crust pastry (ukb-b-2024) Fracture of foot, except ankle All - Inverse variance weighted 0.983975730856407 0.463488512749588 0.033755728881152
Parsnip (ukb-b-2468) Fracture of foot, except ankle rs9398444 -3.84354083840773 1.7487796286045 0.0279603867633428
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs1051547 -7.81494423271637 3.27382798938118 0.016982020380087
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs11931740 8.41536031109491 4.14691943127962 0.0424273331695707
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs12446517 11.2355562140497 4.33680123097248 0.0095767776701959
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs1411451 -7.69317796130784 3.70517026812988 0.0378628972430846
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs1964272 -7.05659364015467 2.92619838661704 0.0158860657963834
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs34162196 -5.33026122138499 2.32062044902076 0.0216237837915721
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle rs7124442 9.55913088515221 4.26330576062537 0.0249492566884226
Fresh fruit (ukb-b-3881) Fracture of foot, except ankle All - Inverse variance weighted -0.594497927707461 0.299639319732969 0.047250811107025
Drinking water (ukb-b-3975) Fracture of foot, except ankle rs35294020 0.391561385347476 0.176010412347638 0.0261048114037984
Drinking water (ukb-b-3975) Fracture of foot, except ankle All - MR Egger 0.304216731798589 0.132835197031063 0.0319648312579795
Bacon (ukb-b-4414) Fracture of foot, except ankle rs117334069 7.03012207937615 2.40328425932292 0.0034421881330674
Bacon (ukb-b-4414) Fracture of foot, except ankle rs66799945 -2.40874183835718 1.12317737406543 0.03198657778205
Bacon (ukb-b-4414) Fracture of foot, except ankle All - MR Egger 2.52272277433988 1.07349963965956 0.0406407251821299
Pork (ukb-b-5185) Fracture of foot, except ankle rs12200757 -4.1493228489818 1.81409186561207 0.022179909327525
Pork (ukb-b-5185) Fracture of foot, except ankle All - Inverse variance weighted -0.878969579666117 0.443275829732108 0.0473791206620402
Baguette (ukb-b-5277) Fracture of foot, except ankle rs113040087 3.8166949526001 1.4333572734495 0.0077501297602012
Baguette (ukb-b-5277) Fracture of foot, except ankle All - Inverse variance weighted 0.748109308189379 0.35689685928183 0.0360688975409462
Couscous (ukb-b-758) Fracture of foot, except ankle rs143108349 7.96844567648059 3.35689774214491 0.017608330995379
Couscous (ukb-b-758) Fracture of foot, except ankle All - Inverse variance weighted 1.9276032780399 0.923714824971715 0.0369066889030931
Soya dessert (ukb-b-998) Fracture of foot, except ankle rs13250489 -12.0732558940111 6.07351162081616 0.0468278116924262
Soya dessert (ukb-b-998) Fracture of foot, except ankle rs147659323 -3.43184111305826 1.71923955180288 0.0459187953908214
Soya dessert (ukb-b-998) Fracture of foot, except ankle rs148405974 22.7192619022589 9.04689171557018 0.0120294855382431
Soya dessert (ukb-b-998) Fracture of foot, except ankle rs72835369 -7.50185351387209 3.47289967612284 0.0307639724533713