ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Oily fish (ukb-b-10546) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 15 2.336952013 1.000152341 0.036116739
Avocado (ukb-b-12236) (👉 📊) Fracture of lumbar spine and pelvis Weighted median 24 -1.9409147 0.845591326 0.021713978
Cereal (ukb-b-15926) (👉 📊) Fracture of lumbar spine and pelvis Weighted median 175 -0.80427825 0.317872083 0.011399926
Cereal (ukb-b-15926) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 175 -0.922223635 0.213253513 1.53e-05
Parsnip (ukb-b-2468) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 20 -1.076427023 0.484603316 0.026333767
Hard cheese (ukb-b-3542) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 12 -2.402218474 0.844410829 0.017403203
Apple (ukb-b-4070) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 18 1.672239097 0.744996669 0.039283509
Pork (ukb-b-5185) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 16 1.098642828 0.492296651 0.025636894
Sushi (ukb-b-5213) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 69 -1.463734027 0.651127695 0.024576291
Scone (ukb-b-5627) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 10 -1.678624164 0.796503706 0.035075066
Courgette (ukb-b-7420) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 19 -3.099079162 1.146517726 0.015079147
Cappuccino (ukb-b-8374) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 21 -1.959550543 0.825424364 0.028292173
Cappuccino (ukb-b-8374) (👉 📊) Fracture of lumbar spine and pelvis Weighted median 21 -0.987171549 0.49529525 0.04625081
Cappuccino (ukb-b-8374) (👉 📊) Fracture of lumbar spine and pelvis Inverse variance weighted 21 -0.993183804 0.370772197 0.007391077
Chocolate biscuits (ukb-b-9886) (👉 📊) Fracture of lumbar spine and pelvis MR Egger 8 2.024866247 0.508459528 0.007263685

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Oily fish (ukb-b-10546) Fracture of lumbar spine and pelvis All - MR Egger 2.33695201305813 1.00015234111318 0.0361167385165384
Avocado (ukb-b-12236) Fracture of lumbar spine and pelvis rs574491624 7.95254807884989 3.89134762005638 0.0409882499427227
Avocado (ukb-b-12236) Fracture of lumbar spine and pelvis rs62196418 -5.41913264936982 2.76021242421173 0.0496110058457148
Avocado (ukb-b-12236) Fracture of lumbar spine and pelvis rs7103110 -5.51649349041981 2.35158216098024 0.0189829989602552
Avocado (ukb-b-12236) Fracture of lumbar spine and pelvis rs77419563 3.27874405134893 1.62243636425221 0.0432925173050161
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs10857964 -4.42264279528062 2.06579302315676 0.0322826298015388
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs117419440 -5.58927193476402 2.67993075976558 0.0370145891541059
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs12887676 6.59091955443445 3.27122845532592 0.0439240561766444
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs1397440 -8.71253261828257 3.06174080913752 0.0044325885131511
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs1604918 -8.57180391040658 3.17474218903948 0.0069339476060813
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs17115145 -6.29536663317578 3.17645555896986 0.04749221859976
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs2450126 -6.98568638898396 2.26816714647126 0.0020708286030434
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs3115230 -6.20322532867511 2.58758135198948 0.0165161064387126
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs7040561 -6.09767341795494 2.67387896855887 0.0225804341818041
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs76187305 -7.69309241912352 2.95842009565358 0.0093113611931192
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis rs834233 5.76731611367886 2.79259517083397 0.0389024357042717
Cereal (ukb-b-15926) Fracture of lumbar spine and pelvis All - Inverse variance weighted -0.922223634659193 0.213253513155846 1.52849536523795e-05
Parsnip (ukb-b-2468) Fracture of lumbar spine and pelvis rs185294054 -14.3906673360594 6.94431137495066 0.0382378633389349
Parsnip (ukb-b-2468) Fracture of lumbar spine and pelvis All - Inverse variance weighted -1.07642702313006 0.484603316185356 0.0263337669601247
Hard cheese (ukb-b-3542) Fracture of lumbar spine and pelvis rs10866415 3.12803692905734 1.32757184506456 0.0184625193426128
Hard cheese (ukb-b-3542) Fracture of lumbar spine and pelvis All - MR Egger -2.40221847413109 0.844410828984257 0.0174032028443187
Apple (ukb-b-4070) Fracture of lumbar spine and pelvis All - MR Egger 1.67223909725615 0.744996669330414 0.0392835085292966
Pork (ukb-b-5185) Fracture of lumbar spine and pelvis All - Inverse variance weighted 1.09864282785836 0.492296651246535 0.0256368942516372
Sushi (ukb-b-5213) Fracture of lumbar spine and pelvis rs140497463 18.3907637497612 8.47130107990209 0.0299350175676167
Sushi (ukb-b-5213) Fracture of lumbar spine and pelvis rs2229360 -5.13851544238568 2.29354440448364 0.025063310276868
Sushi (ukb-b-5213) Fracture of lumbar spine and pelvis rs5996535 -11.7980791463875 5.00798005831364 0.0184800871130422
Sushi (ukb-b-5213) Fracture of lumbar spine and pelvis rs61905205 -22.4883901831076 9.36839628740205 0.0163748163071055
Sushi (ukb-b-5213) Fracture of lumbar spine and pelvis All - Inverse variance weighted -1.46373402715839 0.651127694772441 0.0245762908548551
Scone (ukb-b-5627) Fracture of lumbar spine and pelvis rs12901652 -4.14015461462366 1.77900449025618 0.0199529674803577
Scone (ukb-b-5627) Fracture of lumbar spine and pelvis rs79778360 -5.8432740115443 2.46488812430682 0.017759039813107
Scone (ukb-b-5627) Fracture of lumbar spine and pelvis All - Inverse variance weighted -1.67862416427373 0.796503706356773 0.0350750658335676
Courgette (ukb-b-7420) Fracture of lumbar spine and pelvis rs62432357 4.08869934365616 1.56505238034685 0.0089882692313032
Courgette (ukb-b-7420) Fracture of lumbar spine and pelvis rs77575696 -4.75922381113238 1.56138572983523 0.0023031096407995
Courgette (ukb-b-7420) Fracture of lumbar spine and pelvis All - MR Egger -3.09907916159007 1.14651772577592 0.0150791468694098
Cappuccino (ukb-b-8374) Fracture of lumbar spine and pelvis rs7145645 -5.5086024750981 2.11288862058557 0.0091301259769146
Cappuccino (ukb-b-8374) Fracture of lumbar spine and pelvis All - Inverse variance weighted -0.993183803600779 0.37077219680975 0.0073910769692246
Cappuccino (ukb-b-8374) Fracture of lumbar spine and pelvis All - MR Egger -1.95955054310592 0.825424363560493 0.0282921725711301
Chocolate biscuits (ukb-b-9886) Fracture of lumbar spine and pelvis rs12908565 -3.6169203957148 0.868189040955456 3.09920499786664e-05
Chocolate biscuits (ukb-b-9886) Fracture of lumbar spine and pelvis All - MR Egger 2.02486624741647 0.508459527854226 0.007263685424213