ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other fish (ukb-b-1252) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 25 -2.983111199 1.351512187 0.03754726
Other fish (ukb-b-1252) (👉 📊) Fracture of rib(s), sternum and thoracic spine Weighted median 25 -2.125394295 1.033450904 0.039724796
Other fish (ukb-b-1252) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 25 -1.929283453 0.683038201 0.004734535
Other drink (ukb-b-1310) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 18 -1.074526779 0.496792771 0.030546751
Lamb/mutton (ukb-b-14179) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 128 0.611211343 0.26642405 0.021783046
Vegetarian alternatives (ukb-b-14425) (👉 📊) Fracture of rib(s), sternum and thoracic spine Weighted median 6 -4.786020191 2.264762906 0.034578999
Vegetarian alternatives (ukb-b-14425) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 6 -3.989383878 1.851218465 0.031161492
Side salad (ukb-b-1604) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 17 0.637934237 0.291679951 0.044988397
Espresso (ukb-b-19142) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 33 -1.148939755 0.499813176 0.028422965
Espresso (ukb-b-19142) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 33 -0.642924398 0.29952591 0.031835229
Powdered/instant soup (ukb-b-19931) (👉 📊) Fracture of rib(s), sternum and thoracic spine Simple mode 18 4.312031218 1.874298828 0.034345162
Whole egg (ukb-b-4075) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 6 0.920973894 0.431635713 0.032868718
Feta (ukb-b-4740) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 28 3.116339833 1.495215805 0.047109006
Other bread (ukb-b-4964) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 17 -1.350543908 0.517419431 0.019696699
Other bread (ukb-b-4964) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 17 -0.64049641 0.306674083 0.036750526
Watercress (ukb-b-6181) (👉 📊) Fracture of rib(s), sternum and thoracic spine Weighted median 12 -1.521458159 0.73553897 0.038593567
Courgette (ukb-b-7420) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 19 -2.368178466 0.836436087 0.011520757
Couscous (ukb-b-758) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 17 3.458254171 1.446709943 0.030387952
Other egg (ukb-b-8266) (👉 📊) Fracture of rib(s), sternum and thoracic spine Inverse variance weighted 21 -1.804199106 0.813352423 0.026539459
Cappuccino (ukb-b-8374) (👉 📊) Fracture of rib(s), sternum and thoracic spine Weighted median 21 -1.189726049 0.439768438 0.006823315
Instant coffee (ukb-b-930) (👉 📊) Fracture of rib(s), sternum and thoracic spine MR Egger 21 0.464786854 0.193471162 0.026673938

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other fish (ukb-b-1252) Fracture of rib(s), sternum and thoracic spine rs185411372 -7.68821918364721 3.0637773497141 0.0120939100676656
Other fish (ukb-b-1252) Fracture of rib(s), sternum and thoracic spine rs4780881 -5.56900037012784 2.38590097656806 0.019588974578038
Other fish (ukb-b-1252) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -1.92928345274518 0.683038201385145 0.0047345351324265
Other fish (ukb-b-1252) Fracture of rib(s), sternum and thoracic spine All - MR Egger -2.98311119897134 1.35151218672418 0.0375472600643964
Other drink (ukb-b-1310) Fracture of rib(s), sternum and thoracic spine rs6496597 -5.22543636140671 2.00297039146489 0.0090848770616382
Other drink (ukb-b-1310) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -1.07452677916212 0.496792770602263 0.0305467510334996
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs10883567 -6.89789593438843 3.15174403414942 0.0286261810820559
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs1711171 8.63355773010135 3.57838248023938 0.0158349161037678
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs2135928 9.57775049646138 3.45200705966826 0.0055278908629338
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs2678900 4.70032922137162 2.3005830788148 0.0410421986454998
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs3105056 6.41770115535826 2.30555483865418 0.0053762255887842
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs3909726 6.54325500060918 2.23603018640752 0.0034303977421674
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs7447465 4.96748177894289 2.50461266165188 0.0473302084081901
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine rs8073904 6.21703747686075 2.85529670636722 0.0294529698896675
Lamb/mutton (ukb-b-14179) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted 0.611211342641615 0.266424050282842 0.0217830463750261
Vegetarian alternatives (ukb-b-14425) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -3.98938387832018 1.85121846461627 0.0311614923695284
Side salad (ukb-b-1604) Fracture of rib(s), sternum and thoracic spine rs114485796 1.73844138622508 0.775425715995278 0.0249666294651899
Side salad (ukb-b-1604) Fracture of rib(s), sternum and thoracic spine rs5769096 1.03635524149837 0.460462922070101 0.0244057364025108
Side salad (ukb-b-1604) Fracture of rib(s), sternum and thoracic spine rs7007359 -1.35979409589597 0.6812223833241 0.0459220651187594
Side salad (ukb-b-1604) Fracture of rib(s), sternum and thoracic spine rs72838032 1.88693536323269 0.760265477509207 0.0130668280019046
Side salad (ukb-b-1604) Fracture of rib(s), sternum and thoracic spine All - MR Egger 0.637934236757054 0.291679950751468 0.0449883966557546
Espresso (ukb-b-19142) Fracture of rib(s), sternum and thoracic spine rs115032220 -1.71916939746735 0.744314719976287 0.0209028568089053
Espresso (ukb-b-19142) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -0.642924397571973 0.29952590998911 0.0318352289953337
Espresso (ukb-b-19142) Fracture of rib(s), sternum and thoracic spine All - MR Egger -1.14893975481983 0.499813175679646 0.0284229654459457
Powdered/instant soup (ukb-b-19931) Fracture of rib(s), sternum and thoracic spine rs117888205 5.17995031869211 1.95933065028596 0.008199691053824
Whole egg (ukb-b-4075) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted 0.920973893732042 0.431635712895532 0.032868717527552
Feta (ukb-b-4740) Fracture of rib(s), sternum and thoracic spine rs73105356 11.4098390169985 5.55113798328657 0.0398398638432306
Feta (ukb-b-4740) Fracture of rib(s), sternum and thoracic spine All - MR Egger 3.11633983287133 1.49521580481475 0.04710900585696
Other bread (ukb-b-4964) Fracture of rib(s), sternum and thoracic spine rs73017061 -2.33200102714109 0.85548571492369 0.0064119039339608
Other bread (ukb-b-4964) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -0.640496409627127 0.306674083290544 0.0367505262311995
Other bread (ukb-b-4964) Fracture of rib(s), sternum and thoracic spine All - MR Egger -1.35054390821682 0.517419430994302 0.0196966986536059
Courgette (ukb-b-7420) Fracture of rib(s), sternum and thoracic spine rs77575696 -3.17531809480914 1.30866143702536 0.0152500308260036
Courgette (ukb-b-7420) Fracture of rib(s), sternum and thoracic spine All - MR Egger -2.36817846568247 0.836436086545523 0.0115207567145904
Couscous (ukb-b-758) Fracture of rib(s), sternum and thoracic spine rs140097236 5.23822143857732 2.32299030239438 0.0241366171918793
Couscous (ukb-b-758) Fracture of rib(s), sternum and thoracic spine rs61866889 7.51167847519169 3.80785917163457 0.0485323061109918
Couscous (ukb-b-758) Fracture of rib(s), sternum and thoracic spine All - MR Egger 3.4582541710683 1.44670994261966 0.0303879517972052
Other egg (ukb-b-8266) Fracture of rib(s), sternum and thoracic spine All - Inverse variance weighted -1.80419910634936 0.813352422604039 0.0265394590457452
Instant coffee (ukb-b-930) Fracture of rib(s), sternum and thoracic spine rs143523613 0.911417315867156 0.367398514124314 0.0131112844938725
Instant coffee (ukb-b-930) Fracture of rib(s), sternum and thoracic spine rs148251241 0.481251179083884 0.219355841042847 0.0282405016958183
Instant coffee (ukb-b-930) Fracture of rib(s), sternum and thoracic spine All - MR Egger 0.46478685367039 0.193471161577594 0.0266739375719408