ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Oily fish (ukb-b-10546) (👉 📊) Injuries to the ankle and foot Weighted median 15 -0.691766492 0.350844963 0.04864208
Satsuma (ukb-b-11563) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 18 -0.340705395 0.167327823 0.041734786
Grape (ukb-b-12051) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 8 0.441531613 0.220876519 0.045608622
Unsalted nuts (ukb-b-12217) (👉 📊) Injuries to the ankle and foot Weighted median 15 0.942439491 0.422543423 0.025721113
Unsalted nuts (ukb-b-12217) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 15 0.698498012 0.30750691 0.023117501
Other drink (ukb-b-1310) (👉 📊) Injuries to the ankle and foot MR Egger 18 -1.161160462 0.505486798 0.035446059
Sweetcorn (ukb-b-13567) (👉 📊) Injuries to the ankle and foot Weighted median 20 -0.612059271 0.291407692 0.035697725
Sweetcorn (ukb-b-13567) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 20 -0.50414382 0.200685556 0.01200123
Mozzarella (ukb-b-14505) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 22 1.02477238 0.471019527 0.029581641
Cereal (ukb-b-15926) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 175 -0.247306345 0.116561656 0.033864755
Rose wine (ukb-b-16124) (👉 📊) Injuries to the ankle and foot Weighted median 14 0.777777024 0.350555679 0.026507308
Rose wine (ukb-b-16124) (👉 📊) Injuries to the ankle and foot Weighted mode 14 0.818570971 0.322598637 0.024774653
Dark chocolate (ukb-b-16139) (👉 📊) Injuries to the ankle and foot Simple mode 21 -1.391437286 0.532002292 0.016562743
Dried fruit (ukb-b-16576) (👉 📊) Injuries to the ankle and foot Weighted median 155 -0.459344392 0.190918091 0.016129314
Dried fruit (ukb-b-16576) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 155 -0.271895379 0.128616976 0.034515871
Dried fruit (ukb-b-16576) (👉 📊) Injuries to the ankle and foot Simple mode 155 -1.297322335 0.554867088 0.020669375
Dried fruit (ukb-b-16576) (👉 📊) Injuries to the ankle and foot Weighted mode 155 -1.159838121 0.483590409 0.017663755
Fruit smoothie (ukb-b-1780) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 24 0.538265497 0.232000782 0.020335356
Espresso (ukb-b-19142) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 33 0.425384642 0.180079658 0.01816671
Cheesy biscuits (ukb-b-19847) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 24 0.825583179 0.396629137 0.037388249
Powdered/instant soup (ukb-b-19931) (👉 📊) Injuries to the ankle and foot MR Egger 18 1.995758974 0.84063249 0.030445709
Ham (ukb-b-4442) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 9 -0.342464539 0.159322064 0.03159391
Seeds (ukb-b-4548) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 15 0.985430907 0.455864195 0.030643122
Other bread (ukb-b-4964) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 17 0.42495635 0.20947134 0.04248796
Pork (ukb-b-5640) (👉 📊) Injuries to the ankle and foot MR Egger 82 -1.25738628 0.5927232 0.036986229
Couscous (ukb-b-758) (👉 📊) Injuries to the ankle and foot MR Egger 17 2.225488823 0.872827674 0.022209152
Couscous (ukb-b-758) (👉 📊) Injuries to the ankle and foot Inverse variance weighted 17 1.055381835 0.518909613 0.041967204

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Oily fish (ukb-b-10546) Injuries to the ankle and foot rs75606319 -2.18628527343402 0.891368208658497 0.01417768313513
Satsuma (ukb-b-11563) Injuries to the ankle and foot rs10513870 -1.33581734580625 0.57872205485968 0.0209869490216277
Satsuma (ukb-b-11563) Injuries to the ankle and foot rs76469063 -4.34118160749673 1.9010512880798 0.0223968790096652
Satsuma (ukb-b-11563) Injuries to the ankle and foot All - Inverse variance weighted -0.340705394843897 0.167327822710872 0.0417347861393406
Grape (ukb-b-12051) Injuries to the ankle and foot rs117720571 1.37617353781562 0.693918012712112 0.0473458445416492
Grape (ukb-b-12051) Injuries to the ankle and foot rs139167288 4.20949972909518 2.01625428932635 0.0368174898261118
Grape (ukb-b-12051) Injuries to the ankle and foot All - Inverse variance weighted 0.441531613495829 0.22087651851076 0.045608621821649
Unsalted nuts (ukb-b-12217) Injuries to the ankle and foot rs145713169 1.89079063790937 0.932714904840537 0.0426429514726688
Unsalted nuts (ukb-b-12217) Injuries to the ankle and foot All - Inverse variance weighted 0.69849801163279 0.307506910327765 0.0231175007878004
Other drink (ukb-b-1310) Injuries to the ankle and foot rs149362721 -3.53030788082175 1.49911135151843 0.0185260094884302
Other drink (ukb-b-1310) Injuries to the ankle and foot rs529703549 -1.47538053790549 0.703467524516794 0.0359672659742603
Other drink (ukb-b-1310) Injuries to the ankle and foot All - MR Egger -1.16116046242134 0.505486797512053 0.0354460593378068
Sweetcorn (ukb-b-13567) Injuries to the ankle and foot rs10497125 -1.7639786513353 0.879476535566031 0.0448867401552406
Sweetcorn (ukb-b-13567) Injuries to the ankle and foot rs866596 -2.61455558692477 0.902205801121927 0.003755994673044
Sweetcorn (ukb-b-13567) Injuries to the ankle and foot All - Inverse variance weighted -0.504143820390831 0.200685556107604 0.0120012304309103
Mozzarella (ukb-b-14505) Injuries to the ankle and foot rs117549105 13.2284624390981 5.36786645012652 0.013725053372599
Mozzarella (ukb-b-14505) Injuries to the ankle and foot All - Inverse variance weighted 1.02477237993417 0.47101952733175 0.0295816409121717
Cereal (ukb-b-15926) Injuries to the ankle and foot rs10812904 -4.03839740889896 1.57048788123848 0.0101279905493907
Cereal (ukb-b-15926) Injuries to the ankle and foot rs11097340 3.13871018086601 1.22253628591742 0.0102471465368163
Cereal (ukb-b-15926) Injuries to the ankle and foot rs12523398 -4.66837099258459 1.60376010289471 0.0036039961811863
Cereal (ukb-b-15926) Injuries to the ankle and foot rs13066686 -3.80637907098663 1.62296530940841 0.0190105647420412
Cereal (ukb-b-15926) Injuries to the ankle and foot rs141612194 5.15625 1.93877551020408 0.0078247560311288
Cereal (ukb-b-15926) Injuries to the ankle and foot rs143747365 -1.66973832103589 0.822957927358803 0.0424636513529607
Cereal (ukb-b-15926) Injuries to the ankle and foot rs17599026 7.90336146639984 1.92871022941501 4.17195654381822e-05
Cereal (ukb-b-15926) Injuries to the ankle and foot rs2008342 -3.39069923315 1.52778599168096 0.0264625935221249
Cereal (ukb-b-15926) Injuries to the ankle and foot rs2412770 3.31267471126011 1.58172756483591 0.0362297370857815
Cereal (ukb-b-15926) Injuries to the ankle and foot rs4739095 -3.11683870165402 1.21253575425942 0.0101548068004155
Cereal (ukb-b-15926) Injuries to the ankle and foot rs6087577 -3.08714026089062 1.5053899505403 0.0402937702435773
Cereal (ukb-b-15926) Injuries to the ankle and foot rs7796203 -5.1196381798837 1.71059000797062 0.0027633321504809
Cereal (ukb-b-15926) Injuries to the ankle and foot rs834233 -4.02700318113015 1.40641568386204 0.0041924102398141
Cereal (ukb-b-15926) Injuries to the ankle and foot rs9374896 -1.75163324109206 0.804496048840327 0.0294578210219802
Cereal (ukb-b-15926) Injuries to the ankle and foot All - Inverse variance weighted -0.247306345122255 0.116561655575307 0.033864754978669
Rose wine (ukb-b-16124) Injuries to the ankle and foot rs13224220 0.887072208912709 0.298434965875505 0.0029546817187945
Rose wine (ukb-b-16124) Injuries to the ankle and foot rs35815255 -3.31994192259684 1.28447050983466 0.0097470142380336
Rose wine (ukb-b-16124) Injuries to the ankle and foot rs41273040 1.67434271376329 0.822941815404902 0.0418929366986857
Dark chocolate (ukb-b-16139) Injuries to the ankle and foot rs10273549 3.47725297015358 1.24824465595257 0.0053409925250672
Dark chocolate (ukb-b-16139) Injuries to the ankle and foot rs10806742 3.3968182836657 1.27268653372171 0.0076074260096976
Dark chocolate (ukb-b-16139) Injuries to the ankle and foot rs112868306 5.00087336244541 2.37030567685589 0.034875497576109
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs11073575 -3.11221617880525 1.53925493319971 0.0431869100480827
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs261809 -3.95696977124353 1.4228473980587 0.0054188081892598
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs34819186 -3.35002951512993 1.70614886086543 0.049587680825207
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs35456421 4.30960049853218 1.60671516844231 0.0073130319834905
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs3796183 -4.08581878667774 1.81476722758529 0.0243584062086009
Dried fruit (ukb-b-16576) Injuries to the ankle and foot rs4740634 -3.10164981833194 1.49138562693313 0.0375521270166555
Dried fruit (ukb-b-16576) Injuries to the ankle and foot All - Inverse variance weighted -0.271895378737735 0.128616976119539 0.0345158708135926
Fruit smoothie (ukb-b-1780) Injuries to the ankle and foot rs6051417 -6.91368865811444 2.24623294644675 0.0020846228056686
Fruit smoothie (ukb-b-1780) Injuries to the ankle and foot rs6429985 5.20828489318366 2.53438863105812 0.0398745742924445
Fruit smoothie (ukb-b-1780) Injuries to the ankle and foot All - Inverse variance weighted 0.538265496604794 0.232000781588632 0.02033535569291
Espresso (ukb-b-19142) Injuries to the ankle and foot All - Inverse variance weighted 0.425384641527706 0.180079658336903 0.0181667098099382
Cheesy biscuits (ukb-b-19847) Injuries to the ankle and foot rs150893688 5.17572700385834 1.81657133420409 0.0043832962424316
Cheesy biscuits (ukb-b-19847) Injuries to the ankle and foot All - Inverse variance weighted 0.825583178581021 0.396629136837758 0.0373882493384497
Powdered/instant soup (ukb-b-19931) Injuries to the ankle and foot rs12069309 -3.32580432888114 1.58286943994878 0.0356301181216517
Powdered/instant soup (ukb-b-19931) Injuries to the ankle and foot All - MR Egger 1.99575897417985 0.840632489682752 0.0304457086708571
Ham (ukb-b-4442) Injuries to the ankle and foot rs17151445 -0.780147304129135 0.359278363743681 0.0298987911015437
Ham (ukb-b-4442) Injuries to the ankle and foot All - Inverse variance weighted -0.342464538725015 0.159322063766794 0.0315939100340568
Seeds (ukb-b-4548) Injuries to the ankle and foot rs1441393 3.54619722822154 1.76757494241572 0.0448295816915875
Seeds (ukb-b-4548) Injuries to the ankle and foot rs1870059 2.65579255541614 1.32092569357312 0.0443725775071921
Seeds (ukb-b-4548) Injuries to the ankle and foot All - Inverse variance weighted 0.985430907369015 0.455864194668676 0.0306431218429806
Other bread (ukb-b-4964) Injuries to the ankle and foot rs12950671 4.38730994094196 1.97651527891816 0.026437799387881
Other bread (ukb-b-4964) Injuries to the ankle and foot rs7780072 1.759482793895 0.79790498792913 0.0274450993754595
Other bread (ukb-b-4964) Injuries to the ankle and foot rs9992062 2.76930953433711 0.992917704188096 0.0052860862733435
Other bread (ukb-b-4964) Injuries to the ankle and foot All - Inverse variance weighted 0.424956349566279 0.209471339931696 0.0424879595870112
Pork (ukb-b-5640) Injuries to the ankle and foot rs10896701 -4.20668392347867 1.88158386353679 0.0253704926543614
Pork (ukb-b-5640) Injuries to the ankle and foot rs10972033 4.35626929543193 1.5486481638492 0.0049089338475809
Pork (ukb-b-5640) Injuries to the ankle and foot rs12097622 -4.30229223029279 1.93796947310486 0.0264187676145125
Pork (ukb-b-5640) Injuries to the ankle and foot rs1590402 -3.89541670322774 1.86129125751496 0.0363619089870429
Pork (ukb-b-5640) Injuries to the ankle and foot rs4658626 3.8613597466948 1.79366388233565 0.0313361474216594
Pork (ukb-b-5640) Injuries to the ankle and foot rs4672226 6.02026587862749 1.97385766512377 0.0022884136620454
Pork (ukb-b-5640) Injuries to the ankle and foot All - MR Egger -1.25738628027922 0.592723200164876 0.0369862289862141
Couscous (ukb-b-758) Injuries to the ankle and foot rs140097236 3.48313330556923 1.40623394324223 0.0132520459791635
Couscous (ukb-b-758) Injuries to the ankle and foot All - Inverse variance weighted 1.05538183540235 0.518909613480031 0.0419672039043809
Couscous (ukb-b-758) Injuries to the ankle and foot All - MR Egger 2.22548882251307 0.872827673543356 0.0222091521504839