Ankle and foot (finn-b-Z21_ANKLE_FOOT)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sponge pudding (ukb-b-12067) (👉 📊)	Ankle and foot	MR Egger	15	19.6287004	7.675291702	0.023856733
Crisp (ukb-b-12602) (👉 📊)	Ankle and foot	Inverse variance weighted	9	-4.905741477	2.082944723	0.018512976
Red wine (ukb-b-13556) (👉 📊)	Ankle and foot	Inverse variance weighted	10	4.217973402	1.508952459	0.005185172
Vegetarian alternatives (ukb-b-14425) (👉 📊)	Ankle and foot	Weighted median	6	26.6840384	13.17761796	0.042872336
Scotch pancake (ukb-b-2035) (👉 📊)	Ankle and foot	Simple mode	53	-20.98884803	9.99238342	0.040553565
Milk (ukb-b-2966) (👉 📊)	Ankle and foot	Weighted median	20	-7.527327517	3.285859736	0.021973574
White wine (ukb-b-311) (👉 📊)	Ankle and foot	Weighted median	13	-3.865893363	1.876531533	0.039386397
Tofu (ukb-b-5522) (👉 📊)	Ankle and foot	Simple mode	48	-21.90697336	10.07026279	0.034662714
Tea (ukb-b-6066) (👉 📊)	Ankle and foot	MR Egger	137	-5.734518681	2.204768784	0.01033249
Cheese spread (ukb-b-6185) (👉 📊)	Ankle and foot	Simple mode	24	-21.96638434	9.697513951	0.033232631
Cooked vegetable (ukb-b-8089) (👉 📊)	Ankle and foot	Weighted median	94	-4.848047376	2.246930093	0.030956486
Other grain (ukb-b-8765) (👉 📊)	Ankle and foot	Weighted median	70	-15.52454047	5.391749464	0.003985411
Other grain (ukb-b-8765) (👉 📊)	Ankle and foot	Inverse variance weighted	70	-7.469974709	3.790387884	0.048750432
Other grain (ukb-b-8765) (👉 📊)	Ankle and foot	Weighted mode	70	-17.73948713	6.963089526	0.013076932

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sponge pudding (ukb-b-12067)	Ankle and foot	rs112369617	65.6314822497481	27.7069874948142	0.0178473457148809
Sponge pudding (ukb-b-12067)	Ankle and foot	rs74631368	50.5017612093638	23.7671534453658	0.0335986914577382
Sponge pudding (ukb-b-12067)	Ankle and foot	All - MR Egger	19.6287004000793	7.67529170195961	0.0238567333687039
Crisp (ukb-b-12602)	Ankle and foot	rs10153975	-11.0843613736397	5.00262447180672	0.0267114202115543
Crisp (ukb-b-12602)	Ankle and foot	All - Inverse variance weighted	-4.90574147740948	2.08294472252802	0.0185129763095511
Red wine (ukb-b-13556)	Ankle and foot	rs114966038	12.3974445855347	5.61020060398313	0.027118757487099
Red wine (ukb-b-13556)	Ankle and foot	rs3751395	9.28632245110622	4.25715774357932	0.0291580352332098
Red wine (ukb-b-13556)	Ankle and foot	All - Inverse variance weighted	4.21797340158835	1.50895245885346	0.0051851723232392
Vegetarian alternatives (ukb-b-14425)	Ankle and foot	rs4440163	62.7930341594106	26.3303579971841	0.0170877094258504
Scotch pancake (ukb-b-2035)	Ankle and foot	rs62280577	69.3240599364873	30.3049654860115	0.0221638633492744
Scotch pancake (ukb-b-2035)	Ankle and foot	rs80028008	114.688326504104	49.9523591818597	0.0216785029321863
Milk (ukb-b-2966)	Ankle and foot	rs71413244	28.9420696789448	11.993386780951	0.0158144830647945
Tea (ukb-b-6066)	Ankle and foot	rs10082992	-23.7201563285996	11.5930812986108	0.0407503286112746
Tea (ukb-b-6066)	Ankle and foot	rs11587444	20.7442563137791	9.3281454877145	0.0261595483952885
Tea (ukb-b-6066)	Ankle and foot	rs11715828	-30.5340561014967	12.4262013121914	0.0140012341146175
Tea (ukb-b-6066)	Ankle and foot	rs140303651	-23.2823438766157	10.9495596264463	0.0334760444098841
Tea (ukb-b-6066)	Ankle and foot	rs17576658	-22.9133904993621	11.5345814912619	0.0469783678548861
Tea (ukb-b-6066)	Ankle and foot	rs1941356	29.4766786012065	12.7029280494384	0.0203158269281059
Tea (ukb-b-6066)	Ankle and foot	rs4410790	-7.69902294910556	3.35136841378426	0.0216029496292119
Tea (ukb-b-6066)	Ankle and foot	rs4683352	-29.3924312141985	14.2992513168117	0.0398285755250266
Tea (ukb-b-6066)	Ankle and foot	rs9624470	-12.2505167194957	5.13744143515121	0.0170997459627932
Tea (ukb-b-6066)	Ankle and foot	rs977474	-25.4208885603706	10.4126016353478	0.0146321404846685
Tea (ukb-b-6066)	Ankle and foot	All - MR Egger	-5.73451868059164	2.2047687843269	0.0103324897287776
Cheese spread (ukb-b-6185)	Ankle and foot	rs10090300	47.4771241830065	22.559186637618	0.0353297720073481
Cheese spread (ukb-b-6185)	Ankle and foot	rs73250437	92.8445070694567	44.2911009564946	0.0360614475558094
Cooked vegetable (ukb-b-8089)	Ankle and foot	rs1534749	-37.8308153643769	17.7170233221938	0.0327381004121777
Cooked vegetable (ukb-b-8089)	Ankle and foot	rs7667638	-45.6257632112267	16.2387658537951	0.0049590518232002
Other grain (ukb-b-8765)	Ankle and foot	rs148766918	127.712756885819	65.0422102839601	0.0495838623666108
Other grain (ukb-b-8765)	Ankle and foot	rs74697960	71.5300841306876	35.0354534469262	0.0411864017538273
Other grain (ukb-b-8765)	Ankle and foot	rs77603410	101.199056954	35.7451075872776	0.0046383821788533
Other grain (ukb-b-8765)	Ankle and foot	All - Inverse variance weighted	-7.46997470893491	3.79038788395713	0.0487504317946875