ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Hip osteoarthritis (ieu-a-1169)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Side salad (ukb-b-1604) (👉 📊) Hip osteoarthritis Inverse variance weighted 3 0.97686468 0.46897445 0.037252992
Hot chocolate (ukb-b-16449) (👉 📊) Hip osteoarthritis Inverse variance weighted 7 1.977043189 0.96672191 0.040844979
Dried fruit (ukb-b-16576) (👉 📊) Hip osteoarthritis Inverse variance weighted 99 0.786653079 0.33153386 0.017655329
Ice-cream (ukb-b-17189) (👉 📊) Hip osteoarthritis Weighted median 6 -1.741925187 0.859641609 0.042730073
Non-oily fish (ukb-b-17627) (👉 📊) Hip osteoarthritis MR Egger 28 6.590088712 2.426582862 0.011594602
Non-oily fish (ukb-b-17627) (👉 📊) Hip osteoarthritis Weighted median 28 1.849947072 0.868989037 0.033266695
Non-oily fish (ukb-b-17627) (👉 📊) Hip osteoarthritis Inverse variance weighted 28 1.612291676 0.60484458 0.007684428
Cheesy biscuits (ukb-b-19847) (👉 📊) Hip osteoarthritis Inverse variance weighted 4 -5.600951444 2.306326369 0.015160739
Porridge (ukb-b-29) (👉 📊) Hip osteoarthritis Inverse variance weighted 2 -2.124094221 1.073998389 0.047957557
Green tea (ukb-b-4078) (👉 📊) Hip osteoarthritis Inverse variance weighted 13 -0.014860392 0.00698433 0.033363955
Beer/cider (ukb-b-4961) (👉 📊) Hip osteoarthritis Inverse variance weighted 3 -1.142266942 0.544693834 0.03598643
Processed meat (ukb-b-6324) (👉 📊) Hip osteoarthritis Simple mode 56 -2.899611439 1.339580228 0.034778279
Other meat (ukb-b-770) (👉 📊) Hip osteoarthritis Inverse variance weighted 3 -5.03828953 2.556406818 0.048741253
Yogurt (ukb-b-7753) (👉 📊) Hip osteoarthritis Inverse variance weighted 2 -1.56749875 0.79369905 0.04827628

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Side salad (ukb-b-1604) Hip osteoarthritis All - Inverse variance weighted 0.976864679830315 0.468974450038354 0.0372529922186986
Hot chocolate (ukb-b-16449) Hip osteoarthritis rs4926877 5.29735436843922 2.5749375647195 0.0396597923028801
Hot chocolate (ukb-b-16449) Hip osteoarthritis All - Inverse variance weighted 1.97704318914035 0.966721910069155 0.0408449787953078
Dried fruit (ukb-b-16576) Hip osteoarthritis rs17175518 6.69447295628121 2.88053443746629 0.0201234302556562
Dried fruit (ukb-b-16576) Hip osteoarthritis rs2533273 7.34774856504117 2.77998782980766 0.0082154021310112
Dried fruit (ukb-b-16576) Hip osteoarthritis rs979678 -6.64043884852589 3.01614113427154 0.0276911727374648
Dried fruit (ukb-b-16576) Hip osteoarthritis All - Inverse variance weighted 0.786653078717732 0.331533860169795 0.0176553288147359
Non-oily fish (ukb-b-17627) Hip osteoarthritis rs1603515 7.22306036309393 3.58138536210511 0.0437128220838363
Non-oily fish (ukb-b-17627) Hip osteoarthritis rs56094641 8.29076464746773 2.19308838133069 0.000156572776844
Non-oily fish (ukb-b-17627) Hip osteoarthritis All - Inverse variance weighted 1.6122916755443 0.604844579862844 0.0076844283699137
Non-oily fish (ukb-b-17627) Hip osteoarthritis All - MR Egger 6.59008871204229 2.42658286226632 0.0115946021371802
Cheesy biscuits (ukb-b-19847) Hip osteoarthritis All - Inverse variance weighted -5.60095144363609 2.3063263689093 0.0151607388298603
Porridge (ukb-b-29) Hip osteoarthritis All - Inverse variance weighted -2.12409422076378 1.07399838889635 0.0479575569213795
Green tea (ukb-b-4078) Hip osteoarthritis All - Inverse variance weighted -0.0148603916928433 0.0069843301218568 0.0333639547349696
Beer/cider (ukb-b-4961) Hip osteoarthritis All - Inverse variance weighted -1.14226694192867 0.544693834264844 0.0359864297760018
Processed meat (ukb-b-6324) Hip osteoarthritis rs12143085 -5.21477921566522 2.5873382376631 0.0438523266124737
Processed meat (ukb-b-6324) Hip osteoarthritis rs12245149 -7.01538982067766 2.6542413843105 0.0082154021310112
Processed meat (ukb-b-6324) Hip osteoarthritis rs12593984 5.90526818095056 2.83718266844818 0.0373987213909692
Processed meat (ukb-b-6324) Hip osteoarthritis rs2873054 4.4209977278898 2.12406579116592 0.0373987213909692
Processed meat (ukb-b-6324) Hip osteoarthritis rs73137142 -9.33302329701479 2.80410576667552 0.0008736451131116
Other meat (ukb-b-770) Hip osteoarthritis All - Inverse variance weighted -5.03828952982937 2.55640681784241 0.0487412525876642
Yogurt (ukb-b-7753) Hip osteoarthritis All - Inverse variance weighted -1.56749875023687 0.793699049592792 0.0482762802251514