ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Bone proteoglycan II (prot-c-2666_53_2)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Beef (ukb-b-10829) (👉 📊) Bone proteoglycan II Weighted median 3 4.070876529 1.643985853 0.01327804
Beef (ukb-b-10829) (👉 📊) Bone proteoglycan II Inverse variance weighted 3 3.141784628 1.322185389 0.017491703
Salted peanuts (ukb-b-1099) (👉 📊) Bone proteoglycan II Wald ratio 1 -8.145986338 3.588551213 0.023208004
Other drink (ukb-b-1310) (👉 📊) Bone proteoglycan II Inverse variance weighted 4 4.37949359 2.083857986 0.035585905
Cheese (ukb-b-1489) (👉 📊) Bone proteoglycan II Inverse variance weighted 75 -1.109087694 0.440714667 0.011850459
Cereal (ukb-b-15926) (👉 📊) Bone proteoglycan II MR Egger 59 -5.022469133 2.293738817 0.032658383
Oily fish (ukb-b-2209) (👉 📊) Bone proteoglycan II MR Egger 66 3.934940118 1.950034081 0.047799997
Other cheese (ukb-b-4088) (👉 📊) Bone proteoglycan II Wald ratio 1 -16.13667446 6.763081098 0.017033005
Wholemeal pasta (ukb-b-4150) (👉 📊) Bone proteoglycan II Wald ratio 1 -12.62786796 5.99613881 0.035204358
Crumble (ukb-b-7641) (👉 📊) Bone proteoglycan II Wald ratio 1 12.21489925 5.322401344 0.021733252
Other egg (ukb-b-8266) (👉 📊) Bone proteoglycan II Wald ratio 1 -15.43576486 7.15611608 0.03100542
Cauliflower (ukb-b-905) (👉 📊) Bone proteoglycan II Inverse variance weighted 2 5.726121708 1.662819774 0.000573979

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Beef (ukb-b-10829) Bone proteoglycan II rs2602248 4.52621544327931 2.19399904671115 0.0391128269502144
Beef (ukb-b-10829) Bone proteoglycan II rs7699859 4.43710878493487 2.24777637821116 0.0483818332748312
Beef (ukb-b-10829) Bone proteoglycan II All - Inverse variance weighted 3.14178462768609 1.32218538888479 0.0174917025382293
Salted peanuts (ukb-b-1099) Bone proteoglycan II rs28868570 -8.14598633783394 3.58855121338685 0.0232080043271615
Other drink (ukb-b-1310) Bone proteoglycan II rs6594004 7.63395044316107 3.57563430675357 0.0327616680879824
Other drink (ukb-b-1310) Bone proteoglycan II All - Inverse variance weighted 4.37949359020801 2.08385798550086 0.0355859045803796
Cheese (ukb-b-1489) Bone proteoglycan II rs11735256 -9.35987810391306 3.75597341057884 0.0127026764430818
Cheese (ukb-b-1489) Bone proteoglycan II rs28415940 -8.27253708836429 3.86566950205486 0.032354675721062
Cheese (ukb-b-1489) Bone proteoglycan II rs4692708 7.95665928933183 3.54259392523999 0.0247041284462421
Cheese (ukb-b-1489) Bone proteoglycan II rs8059277 -11.5145467106778 3.7914246479534 0.0023894753509024
Cheese (ukb-b-1489) Bone proteoglycan II All - Inverse variance weighted -1.10908769415003 0.440714666612956 0.0118504589419278
Cereal (ukb-b-15926) Bone proteoglycan II rs10809287 -11.0818112694741 4.85193244139582 0.0223715603384344
Cereal (ukb-b-15926) Bone proteoglycan II rs2456141 10.7608019203414 5.21609397226173 0.0391126271669134
Cereal (ukb-b-15926) Bone proteoglycan II rs2875243 16.6002772562163 5.44092512327373 0.0022807852167185
Cereal (ukb-b-15926) Bone proteoglycan II rs62442924 -10.8319129048221 4.22791004563699 0.0104070796294767
Cereal (ukb-b-15926) Bone proteoglycan II All - MR Egger -5.02246913331958 2.2937388170387 0.032658383446253
Oily fish (ukb-b-2209) Bone proteoglycan II rs2827161 9.60658737419945 4.1641055324234 0.021054874851661
Oily fish (ukb-b-2209) Bone proteoglycan II rs4974084 -12.980571806454 4.73225570766515 0.0060880904871443
Oily fish (ukb-b-2209) Bone proteoglycan II All - MR Egger 3.93494011783146 1.95003408053902 0.0477999972911569
Other cheese (ukb-b-4088) Bone proteoglycan II rs7214411 -16.1366744559189 6.76308109796151 0.0170330047468179
Wholemeal pasta (ukb-b-4150) Bone proteoglycan II rs1761938 -12.6278679640988 5.99613881026474 0.0352043577136519
Crumble (ukb-b-7641) Bone proteoglycan II rs11213675 12.2148992484359 5.32240134424905 0.0217332517470495
Other egg (ukb-b-8266) Bone proteoglycan II rs76351643 -15.4357648593255 7.1561160797466 0.0310054197309075
Cauliflower (ukb-b-905) Bone proteoglycan II rs848788 7.07306145257022 2.40253522686656 0.0032400098229648
Cauliflower (ukb-b-905) Bone proteoglycan II All - Inverse variance weighted 5.72612170752948 1.66281977360866 0.0005739789043151