ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Unsalted nuts (ukb-b-12217) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 15 -0.025323451 0.011614739 0.048209967
Mixed vegetable (ukb-b-13155) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 13 0.006381773 0.002775654 0.021493824
Cheese (ukb-b-1489) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 203 -0.012231424 0.005407074 0.024760143
Cheese (ukb-b-1489) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 203 -0.0048718 0.002175935 0.025159458
Cheese (ukb-b-1489) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 203 -0.004953659 0.001495173 0.00092268
Cereal (ukb-b-15926) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 175 -0.008750391 0.002977519 0.00329465
Salted nuts (ukb-b-15960) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 23 -0.029505235 0.01260598 0.029203107
Salted nuts (ukb-b-15960) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 23 -0.014408962 0.006855118 0.035559622
Hot chocolate (ukb-b-16449) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 18 0.015922709 0.007700137 0.038654378
Non-oily fish (ukb-b-17627) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 68 -0.035198909 0.012055496 0.004788393
Low fat hard cheese (ukb-b-18079) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 17 0.023107129 0.010736605 0.048075584
Oily fish (ukb-b-2209) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 169 -0.004630409 0.001847457 0.012197807
Latte (ukb-b-3000) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 9 -0.013405322 0.006199506 0.030593442
Standard tea (ukb-b-3291) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 15 5.16e-05 1.89e-05 0.006281194
Standard tea (ukb-b-3291) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 15 3.32e-05 1.33e-05 0.012640654
Croissant (ukb-b-4007) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 26 0.029996079 0.011208271 0.01320556
Croissant (ukb-b-4007) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 26 0.020493789 0.00618513 0.000921702
Pork (ukb-b-5185) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 17 -0.021745833 0.00916745 0.031495771
Coffee (ukb-b-5237) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 116 0.012520106 0.006264449 0.048031877
Scone (ukb-b-5627) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 9 0.022480539 0.010499944 0.032272806
Scone (ukb-b-5627) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 9 0.016091755 0.007588559 0.033961517
Tea (ukb-b-6066) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted mode 141 0.011904905 0.005652622 0.036981757
Crumble (ukb-b-7641) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis MR Egger 25 0.037737612 0.011824201 0.004059724
Stewed fruit (ukb-b-8676) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Weighted median 8 -0.019934122 0.009909838 0.044267525
Stewed fruit (ukb-b-8676) (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis Inverse variance weighted 8 -0.019967598 0.008077641 0.013437493

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Unsalted nuts (ukb-b-12217) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger -0.0253234514514979 0.0116147393151177 0.0482099672587771
Mixed vegetable (ukb-b-13155) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted 0.0063817726298154 0.0027756542708153 0.0214938236515414
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs12951057 -0.034835387153344 0.0163266637360144 0.0328714364329226
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs1873036 0.0473020022246941 0.0232331757508343 0.0417535692842907
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs28415940 -0.0507110771289305 0.0220071256384933 0.0212056623482958
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs2968940 -0.0580457803844901 0.0223367546432063 0.0093586593487603
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs34205186 -0.0528268444461232 0.0242939026808563 0.0296683679329294
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs3733421 0.0535886297187866 0.0240381653339236 0.0257929887906722
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs4655801 0.0593114832575376 0.0225496248731006 0.0085318398043238
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs4721694 -0.0651499501055021 0.0244246897781028 0.0076444986785017
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs61953351 -0.0514230600553683 0.0201511662966313 0.0107147964703071
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs72752436 -0.0679091025041452 0.0222970111814974 0.0023217064795822
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs77837876 0.0514966267312861 0.0241318298241036 0.0328451489736624
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis rs7936836 -0.0338830024712474 0.0162853944877978 0.0374727238326982
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted -0.0049536588752716 0.0014951733386179 0.0009226796427046
Cheese (ukb-b-1489) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger -0.0122314239162754 0.0054070740867497 0.0247601430826954
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs10124390 0.092868893958581 0.0309176075208437 0.0026667065906104
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs10812904 -0.0593627082553613 0.0286692562720085 0.0383957151609809
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs186852039 0.0877034917136708 0.0286525449594305 0.0022064920076052
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs2412770 0.0616284830337336 0.0291573072829104 0.034544760108571
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs2472297 -0.0473214398364855 0.0181496107697549 0.0091259957766149
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs2880666 0.0680785904625542 0.0291097919898182 0.019351819283735
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs3021529 -0.0721305297560488 0.0296394090477064 0.0149494163220688
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs6486751 0.0689400132805059 0.0303333965184607 0.0230416743922832
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs678870 0.0611145393897183 0.0310929231909214 0.0493511938919198
Cereal (ukb-b-15926) Non-cancer illness code self-reported: rheumatoid arthritis rs9870005 0.0621478848024607 0.0292131811085907 0.0333875347765096
Salted nuts (ukb-b-15960) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted -0.0144089617012201 0.0068551181403757 0.0355596224865428
Salted nuts (ukb-b-15960) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger -0.0295052347800927 0.0126059802392221 0.0292031071796854
Hot chocolate (ukb-b-16449) Non-cancer illness code self-reported: rheumatoid arthritis rs112847589 0.0643456017877016 0.0223425313749555 0.0039772533810105
Hot chocolate (ukb-b-16449) Non-cancer illness code self-reported: rheumatoid arthritis rs76187757 -0.0471879115547238 0.0234561585915298 0.0442463666816987
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs10844370 -0.0987793633038063 0.0333369108443934 0.0030459433224336
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs117427411 -0.0671462463804448 0.0318592796858026 0.035066613048038
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs13150190 0.0698735938067013 0.0329130881819281 0.0337561239949638
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs150075454 -0.0716512275613442 0.0327619622007332 0.0287407052943474
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs56848830 -0.0769430020714151 0.0340428341440707 0.0238099555137468
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs76477280 -0.0934751309973281 0.0426518558182484 0.0284095477588339
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis rs78769094 -0.0746996961906988 0.0328382799719561 0.0229194345777358
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger -0.0351989088448192 0.0120554963735248 0.0047883934078299
Low fat hard cheese (ukb-b-18079) Non-cancer illness code self-reported: rheumatoid arthritis rs142296911 0.0549548977614128 0.0223235074996126 0.0138260947784811
Low fat hard cheese (ukb-b-18079) Non-cancer illness code self-reported: rheumatoid arthritis rs9895448 -0.0533950939680637 0.0238199409221285 0.0249863821836813
Low fat hard cheese (ukb-b-18079) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger 0.0231071289002451 0.010736605321187 0.0480755844176791
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs1053924 -0.0524715148122976 0.021946028065406 0.0168055524547
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs11648715 0.0567210102637861 0.0284084730829763 0.0458661542741707
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs11767283 -0.0495569638158825 0.0175161682745353 0.0046662691142125
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs12855717 -0.0550075226087099 0.0209310863628187 0.0085880944866721
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs12983532 0.0439482430262519 0.0222197990963068 0.0479415002585741
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs303817 -0.0533514237954624 0.0217184220796913 0.0140295645490058
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs3847799 -0.0701532476042264 0.0260810877221722 0.0071492077952399
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs6119946 -0.0551049155698353 0.0266943995911163 0.0389904648643704
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs730925 -0.0511175235593562 0.0249363921350577 0.0403725724519554
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs77258251 0.0561020070485076 0.0266500425340974 0.0352793305613612
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis rs7749444 0.059983099821273 0.0285672452060331 0.0357538374638006
Oily fish (ukb-b-2209) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted -0.0046304094390666 0.0018474568133443 0.0121978070039239
Latte (ukb-b-3000) Non-cancer illness code self-reported: rheumatoid arthritis rs72773940 -0.0393960018149305 0.0190183628259535 0.0383147294002633
Latte (ukb-b-3000) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted -0.0134053218030704 0.0061995058909047 0.0305934418265546
Standard tea (ukb-b-3291) Non-cancer illness code self-reported: rheumatoid arthritis rs2472297 7.34881214793044e-05 2.81855498408033e-05 0.0091259957766149
Standard tea (ukb-b-3291) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted 3.32462444507393e-05 1.33319024856431e-05 0.0126406541227315
Croissant (ukb-b-4007) Non-cancer illness code self-reported: rheumatoid arthritis rs111997347 0.064093607762595 0.0311230687422859 0.0394597494955882
Croissant (ukb-b-4007) Non-cancer illness code self-reported: rheumatoid arthritis rs117892082 0.0857531356483218 0.0316662035250919 0.0067683217898826
Croissant (ukb-b-4007) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted 0.0204937887034685 0.0061851300326521 0.0009217018664975
Croissant (ukb-b-4007) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger 0.0299960786163044 0.011208270687718 0.0132055598231192
Pork (ukb-b-5185) Non-cancer illness code self-reported: rheumatoid arthritis rs79938133 -0.0374852191085958 0.0190381395316149 0.0489583849719083
Pork (ukb-b-5185) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger -0.0217458333367778 0.0091674498339055 0.0314957707711164
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs1057868 0.0417090457072112 0.0141218691888586 0.0031418503565901
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs11206378 -0.0952794072088999 0.0335006561101358 0.004453626990301
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs116814395 0.0854678313989868 0.0341580731716802 0.0123449690888848
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs13054099 -0.0632230438776362 0.0268834723549551 0.0186856317089983
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs144620429 0.101160586862791 0.0334141037354738 0.0024660066248384
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs2472297 0.0161419644163647 0.0061910705217039 0.0091259957766149
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs61928609 -0.0498706764875598 0.0233304368487153 0.0325508419182332
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs6937318 -0.172580523692299 0.029943446315185 8.23632668348969e-09
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs7224815 0.0534434909117696 0.0238890628165227 0.0252763355136852
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis rs7590617 -0.0846182062643891 0.0339775482927792 0.0127593902750349
Coffee (ukb-b-5237) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger 0.0125201059502756 0.0062644490363469 0.0480318770538976
Scone (ukb-b-5627) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted 0.0160917548388076 0.0075885593023491 0.0339615166191625
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs10741694 0.0362483254130648 0.0175821963915567 0.0392411230492574
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs1453548 -0.0470816406074325 0.0202804053547604 0.0202580677559379
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs1640297 0.065784825955042 0.0247265977142968 0.0078027419032081
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs17685 0.0368210530879452 0.0123072120699746 0.0027731309068464
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs2207055 0.058659464115534 0.0244067517044205 0.0162429046518175
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs2289002 -0.0584564049548635 0.0260893684579741 0.0250505902468798
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs2472297 0.0140617823875768 0.0053932398917992 0.0091259957766149
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs457534 0.049966188231396 0.0253576968838954 0.048786303389923
Tea (ukb-b-6066) Non-cancer illness code self-reported: rheumatoid arthritis rs977474 0.0324033000785077 0.0157560843475826 0.0397287693247292
Crumble (ukb-b-7641) Non-cancer illness code self-reported: rheumatoid arthritis rs72876166 0.0699523241617069 0.0330606301822333 0.0343550200518748
Crumble (ukb-b-7641) Non-cancer illness code self-reported: rheumatoid arthritis All - MR Egger 0.0377376123827273 0.0118242005763402 0.0040597241093327
Stewed fruit (ukb-b-8676) Non-cancer illness code self-reported: rheumatoid arthritis All - Inverse variance weighted -0.0199675982600432 0.0080776413836184 0.0134374929097457