ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Pear (ukb-b-10793) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 16 0.005106709 0.002578557 0.047652715
Pineapple (ukb-b-1164) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 16 0.01990003 0.00718691 0.015073967
Pineapple (ukb-b-1164) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 16 0.009037272 0.004321343 0.036500195
Pineapple (ukb-b-1164) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 16 0.006404288 0.00323428 0.047689179
Chocolate bar (ukb-b-117) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 12 -0.008088168 0.003201708 0.030065891
Unsalted nuts (ukb-b-12217) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 15 -0.008108909 0.003988128 0.042026063
Non-oily fish (ukb-b-17627) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 68 0.005933994 0.00193598 0.00217589
Single crust pastry (ukb-b-2024) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 15 -0.012847868 0.005384507 0.032931475
Scotch pancake (ukb-b-2035) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 55 -0.015578645 0.006258165 0.015971918
Beef (ukb-b-2862) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 102 -0.010890511 0.00513137 0.036279136
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 35 0.010657591 0.00433587 0.013971111
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 35 0.009666383 0.003440717 0.004963244
Seeds (ukb-b-4548) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 15 0.024966733 0.009673952 0.022821097
Yorkshire pudding (ukb-b-5605) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 17 0.008850195 0.004135458 0.032348621
Mango (ukb-b-6218) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 27 -0.0081154 0.003146215 0.009896728
Mango (ukb-b-6218) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted mode 27 -0.007212102 0.003464937 0.047380124
Processed meat (ukb-b-6324) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 129 0.008433592 0.004008095 0.037337993
Fresh tomato (ukb-b-730) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Weighted median 10 -0.003021924 0.001395103 0.030304037
Fresh tomato (ukb-b-730) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 10 -0.002797844 0.001057944 0.008178654
Other grain (ukb-b-8765) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 70 0.009056017 0.004608796 0.049420922
Other cereal (ukb-b-8917) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 13 0.012856915 0.005276782 0.014829895
Cauliflower (ukb-b-905) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis MR Egger 14 0.011228548 0.003857299 0.013057115
Fortified wine (ukb-b-9524) (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis Inverse variance weighted 21 -0.010827415 0.003801954 0.004401492

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Pineapple (ukb-b-1164) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted 0.0064042877318951 0.0032342801289661 0.0476891792743045
Pineapple (ukb-b-1164) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger 0.0199000301708811 0.0071869100205427 0.0150739665702684
Chocolate bar (ukb-b-117) Non-cancer illness code self-reported: ankylosing spondylitis rs4656997 0.0149845431319177 0.0060041247630899 0.0125705977710475
Chocolate bar (ukb-b-117) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger -0.0080881678568229 0.0032017076672057 0.0300658909066359
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs10482944 0.0341560414760056 0.0168173296489467 0.0422547234114729
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs10844370 0.0510605556731263 0.0170584545152221 0.0027600569247099
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs12555454 0.0322975667046079 0.0153102095218268 0.0348976180833199
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs1260326 0.0407767173215374 0.0139573393736772 0.0034832220667022
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs12638455 0.0359278817971573 0.017000445094913 0.0345708666218047
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs6953095 -0.0417535361149293 0.0164336230213275 0.011061866939152
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis rs7432182 0.0337961050350431 0.0168275677125235 0.0446032130618769
Non-oily fish (ukb-b-17627) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted 0.0059339943367898 0.0019359800206503 0.0021758897000933
Single crust pastry (ukb-b-2024) Non-cancer illness code self-reported: ankylosing spondylitis rs144508914 -0.0291858013360719 0.0126118738442432 0.0206593499805575
Single crust pastry (ukb-b-2024) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger -0.0128478678330879 0.0053845067855328 0.0329314749917643
Scotch pancake (ukb-b-2035) Non-cancer illness code self-reported: ankylosing spondylitis rs116853849 -0.0454459756699735 0.0231554592928431 0.0496872910690433
Scotch pancake (ukb-b-2035) Non-cancer illness code self-reported: ankylosing spondylitis rs2038940 0.0448729156729644 0.0227790840640688 0.04884782976921
Scotch pancake (ukb-b-2035) Non-cancer illness code self-reported: ankylosing spondylitis rs78717230 0.0501978673661402 0.0248196004637813 0.0431237862359711
Scotch pancake (ukb-b-2035) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger -0.0155786448500585 0.006258164897218 0.0159719177150149
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs10247400 0.0359355425363416 0.0162841208694814 0.0273291313018843
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs12113634 0.0373434272852413 0.0150812075210097 0.0132805417835377
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs12257513 0.0360007183244356 0.0166645040810586 0.0307476417469681
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs12652806 0.0487363259556254 0.0162597458889822 0.0027232814030029
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs140748046 0.0390941678520626 0.0162942057847321 0.0164278825993792
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs17501421 -0.0344368528900987 0.0154684429702006 0.0259964376806699
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs2965199 0.0343656556023518 0.0160852244299697 0.0326408394012276
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs60255715 -0.0307598013830079 0.0154906631736071 0.0470667058453643
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs645040 -0.0309568516247701 0.0149217312998161 0.038022205642712
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis rs72779821 0.04053084758793 0.015774072650394 0.0101857171067896
Beef (ukb-b-2862) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger -0.0108905105966654 0.0051313697940993 0.0362791361693809
Vegetarian sausages/burgers (ukb-b-3383) Non-cancer illness code self-reported: ankylosing spondylitis rs116262913 0.0380415106446257 0.016150558635015 0.0185012815004942
Vegetarian sausages/burgers (ukb-b-3383) Non-cancer illness code self-reported: ankylosing spondylitis rs143388183 0.0392467055865078 0.0188444894658741 0.037282026725797
Vegetarian sausages/burgers (ukb-b-3383) Non-cancer illness code self-reported: ankylosing spondylitis rs79192051 0.0482218985268303 0.0185834413800095 0.0094622495288324
Vegetarian sausages/burgers (ukb-b-3383) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted 0.0096663831193931 0.003440716823055 0.0049632444751599
Seeds (ukb-b-4548) Non-cancer illness code self-reported: ankylosing spondylitis rs1713456 -0.0386886282951885 0.0161548266485384 0.0166264874630779
Seeds (ukb-b-4548) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger 0.0249667332712427 0.0096739518907301 0.0228210970459466
Yorkshire pudding (ukb-b-5605) Non-cancer illness code self-reported: ankylosing spondylitis rs184006295 -0.0509949793806526 0.01178347030401 1.50694534078828e-05
Yorkshire pudding (ukb-b-5605) Non-cancer illness code self-reported: ankylosing spondylitis rs79273432 -0.0209828699487182 0.0096085243437046 0.0289786730235301
Mango (ukb-b-6218) Non-cancer illness code self-reported: ankylosing spondylitis rs1051412 -0.0519085125719479 0.0187014979884317 0.0055094200579304
Mango (ukb-b-6218) Non-cancer illness code self-reported: ankylosing spondylitis rs11623618 -0.0516342394267466 0.0198780278837916 0.0093890513054238
Mango (ukb-b-6218) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted -0.008115399739872 0.0031462149041829 0.0098967280993514
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs12153596 0.0280794845467648 0.0126246479337597 0.0261363621852618
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs188029213 0.0464430733533724 0.0126125285719741 0.0002311421048293
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs2837899 -0.0324585682677896 0.0130129897937335 0.0126198508689301
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs2873054 0.0228727904085511 0.0097314908758341 0.018753793526543
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs72681540 0.0291753772262247 0.0122574577659323 0.0173025686654674
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis rs7521527 -0.0277398818513774 0.0125664824975625 0.0272826361525954
Processed meat (ukb-b-6324) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger 0.0084335920365404 0.0040080950470421 0.0373379927086162
Fresh tomato (ukb-b-730) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted -0.002797844136019 0.0010579444046398 0.0081786539190159
Other grain (ukb-b-8765) Non-cancer illness code self-reported: ankylosing spondylitis rs138081174 0.0942129380170099 0.0388778919144937 0.0153800643121364
Other grain (ukb-b-8765) Non-cancer illness code self-reported: ankylosing spondylitis rs144141363 -0.0961596007365866 0.0404030823637733 0.0173123302394096
Other grain (ukb-b-8765) Non-cancer illness code self-reported: ankylosing spondylitis rs74504207 0.0842402269286196 0.040256297998869 0.0363851035340998
Other grain (ukb-b-8765) Non-cancer illness code self-reported: ankylosing spondylitis rs75885888 0.0797402782563238 0.0383692539831525 0.0376878357885612
Other grain (ukb-b-8765) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted 0.0090560170389013 0.0046087955134151 0.0494209216175155
Other cereal (ukb-b-8917) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted 0.0128569154266806 0.0052767823150339 0.0148298950220393
Cauliflower (ukb-b-905) Non-cancer illness code self-reported: ankylosing spondylitis rs17756840 -0.0140943317948452 0.0068282943525385 0.039007549881654
Cauliflower (ukb-b-905) Non-cancer illness code self-reported: ankylosing spondylitis rs55662076 0.0130291702519275 0.0064149196236758 0.0422475866383341
Cauliflower (ukb-b-905) Non-cancer illness code self-reported: ankylosing spondylitis All - MR Egger 0.0112285480423734 0.0038572994692691 0.0130571151415517
Fortified wine (ukb-b-9524) Non-cancer illness code self-reported: ankylosing spondylitis rs274958 -0.0539606462806023 0.0187569879268615 0.0040169324619247
Fortified wine (ukb-b-9524) Non-cancer illness code self-reported: ankylosing spondylitis rs77439809 -0.0423962551938148 0.0183428531355739 0.0208150299889506
Fortified wine (ukb-b-9524) Non-cancer illness code self-reported: ankylosing spondylitis rs79482515 -0.0370098415578977 0.0158004816081524 0.0191640888470036
Fortified wine (ukb-b-9524) Non-cancer illness code self-reported: ankylosing spondylitis All - Inverse variance weighted -0.0108274149598055 0.0038019539238636 0.0044014920224167