ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified (ukb-b-11045)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Pear (ukb-b-10793) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Weighted median 6 0.00741726 0.003392625 0.028794415
Pear (ukb-b-10793) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 6 0.007080259 0.002695388 0.008619074
Muesli (ukb-b-11004) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Weighted median 6 -0.009513315 0.003642794 0.009013447
Muesli (ukb-b-11004) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 6 -0.008187562 0.002653913 0.002034898
Cottage cheese (ukb-b-14171) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Weighted median 3 -0.036039202 0.014845271 0.015196772
Cottage cheese (ukb-b-14171) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 3 -0.029944686 0.011607377 0.009885816
Shellfish (ukb-b-143) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Wald ratio 1 0.062588696 0.025951767 0.015876966
Cheese (ukb-b-1489) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Weighted median 109 -0.003970344 0.001497057 0.007999308
Cheese (ukb-b-1489) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 109 -0.004799741 0.000995696 1.43e-06
White pasta (ukb-b-2512) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 3 0.008236471 0.004175244 0.048530638
Porridge (ukb-b-29) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 2 0.01017555 0.004540622 0.025025856
Vegetarian sausages/burgers (ukb-b-3383) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 2 0.028374386 0.011294547 0.011997428
Cheese spread (ukb-b-6185) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 2 -0.025940588 0.012401605 0.036464273
Crumble (ukb-b-7641) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 4 -0.017312947 0.007771762 0.025902303
Poultry (ukb-b-8006) (👉 📊) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified Inverse variance weighted 43 0.004000689 0.001965524 0.041807566

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Pear (ukb-b-10793) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs4744 0.0132616497899517 0.0066850732133751 0.0472814508850475
Pear (ukb-b-10793) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted 0.0070802590792504 0.002695388281825 0.0086190742658471
Muesli (ukb-b-11004) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs218011 -0.0150747266739645 0.0059130944583633 0.0107914541809476
Muesli (ukb-b-11004) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted -0.0081875624767008 0.0026539126742504 0.002034897872666
Cottage cheese (ukb-b-14171) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs566351 -0.0398464776449634 0.0188477811366571 0.0345049895432554
Cottage cheese (ukb-b-14171) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted -0.0299446857830405 0.0116073766930272 0.0098858157256877
Shellfish (ukb-b-143) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs12487739 0.062588695574854 0.0259517669956628 0.0158769661918745
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs10138053 0.0269089452051253 0.0112425571515971 0.0166889480390376
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs2644109 -0.0228720342833724 0.0110665443109024 0.0387555547536765
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs4681981 -0.0305074742081521 0.0094580294465306 0.0012572495890651
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs4692708 -0.0223806840554522 0.0092208312400711 0.0152163998205964
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs61734410 -0.0184776029782635 0.0082631800168127 0.0253427952326909
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs6685323 -0.0242401012996072 0.009615728735423 0.0117061660298506
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs67967503 -0.0267741693893408 0.0112816072047108 0.0176319225419422
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs6873324 -0.0206748633441803 0.009552121571582 0.0304316456357045
Cheese (ukb-b-1489) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted -0.0047997409090254 0.00099569610923 1.43207642418697e-06
White pasta (ukb-b-2512) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs10804975 0.0166280550521624 0.0073686143899691 0.0240327424014251
White pasta (ukb-b-2512) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted 0.0082364711479327 0.0041752438823474 0.0485306382226274
Porridge (ukb-b-29) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted 0.0101755496535754 0.0045406221783245 0.0250258560023667
Vegetarian sausages/burgers (ukb-b-3383) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs16871519 0.0326498695711301 0.0153164290924376 0.0330323886453186
Vegetarian sausages/burgers (ukb-b-3383) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted 0.0283743858750664 0.0112945466845813 0.0119974275524092
Cheese spread (ukb-b-6185) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs36100673 -0.0361731356895902 0.0183517865516406 0.0487128798295375
Cheese spread (ukb-b-6185) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted -0.0259405881414333 0.0124016051337883 0.0364642729509649
Crumble (ukb-b-7641) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs11213675 -0.0317294515742089 0.0147351221672965 0.0312934404380065
Crumble (ukb-b-7641) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted -0.017312947229552 0.007771761926085 0.0259023027951916
Poultry (ukb-b-8006) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs17767108 0.0291349952351842 0.0139774017733495 0.0371205534379112
Poultry (ukb-b-8006) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified rs437029 0.028502089513817 0.0136746378902658 0.0371326097544071
Poultry (ukb-b-8006) Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified All - Inverse variance weighted 0.0040006885170228 0.0019655244120256 0.0418075658025162