ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Chocolate bar (ukb-b-117) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 5 -0.009876725 0.003862596 0.010557385
Vegetable pieces (ukb-b-12566) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 5 0.010583134 0.004492702 0.018491428
Cheese (ukb-b-1489) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 172 -0.003218884 0.001213818 0.00800483
Cereal (ukb-b-15926) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 148 -0.004335153 0.001809108 0.016561839
Poultry (ukb-b-16010) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 4 0.011135187 0.005647988 0.048663114
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint MR Egger 140 -0.02417046 0.008506537 0.005172957
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 140 -0.005671728 0.002592675 0.028698964
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 140 -0.004689939 0.001866179 0.011966715
Grapefruit (ukb-b-18758) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint MR Egger 5 -0.401714651 0.090609812 0.021326264
Cherry (ukb-b-2221) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 6 0.019006812 0.009371636 0.042547895
Lettuce (ukb-b-2867) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 5 -0.005917426 0.002945029 0.044506063
Danish pastry (ukb-b-447) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 3 -0.029934673 0.014639662 0.040877995
Milk chocolate (ukb-b-4569) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 6 0.014126901 0.006842321 0.038957476
Milk chocolate (ukb-b-4569) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 6 0.018597985 0.005258221 0.0004048
Lamb (ukb-b-530) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 5 -0.018327759 0.00872257 0.035624476
Lamb (ukb-b-530) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 5 -0.016449818 0.006675595 0.013733001
Spinach (ukb-b-812) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 4 0.0170871 0.008426102 0.042572775
Other grain (ukb-b-8765) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Weighted median 5 -0.067515926 0.029706733 0.023041353
Other grain (ukb-b-8765) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 5 -0.054481511 0.024314453 0.025045205
Fortified wine (ukb-b-9524) (👉 📊) Operative procedures - secondary OPCS: Z81.4 Shoulder joint Inverse variance weighted 4 -0.025101761 0.012684033 0.047815469

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Chocolate bar (ukb-b-117) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0098767252860142 0.0038625955899091 0.0105573845882268
Vegetable pieces (ukb-b-12566) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs55998069 0.0155762637887362 0.0074695127637906 0.0370409987219253
Vegetable pieces (ukb-b-12566) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs585477 0.0150852262631926 0.007534854521118 0.0452783442314372
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs1931805 -0.0327864169100132 0.0145431811527108 0.0241698513647873
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs215629 0.0382624350507562 0.0173515859647247 0.0274452472027823
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs221418 0.0363359476631285 0.0179790162327256 0.0432777162173992
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs2352974 -0.0391320392903457 0.0127118340093259 0.0020811923873278
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs34205186 0.041409267320749 0.0175317047375329 0.0181783741699925
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs4692708 -0.0312202473896455 0.0144383494684246 0.0305939696108294
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs66905828 0.0419164424750752 0.0177157074783281 0.0179784876106116
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs678349 -0.0393609814770267 0.0177586721193168 0.0266615744867653
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs67967503 -0.0355191492150273 0.0176651157565602 0.0443577465773513
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0032188839085129 0.0012138184632182 0.0080048304369371
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10057775 -0.036089828401392 0.0148781035782579 0.015278858983821
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10260232 -0.0550552965285154 0.0217000686212764 0.0111774249299835
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10799311 -0.0419216590938411 0.0205642593106138 0.0414930736489315
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10829656 -0.0542348295770375 0.0209577834717076 0.0096587332179957
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10879791 -0.0593123966640801 0.0223502989406323 0.0079599709554597
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs11670024 -0.0437315912412406 0.0180248447980814 0.0152585291949855
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs11876432 -0.0490779967356344 0.0213818947722145 0.0217155796163799
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs1966434 -0.0525716398594934 0.0194751545777613 0.0069460259709002
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs491711 -0.0539183813149677 0.0170460709244129 0.0015610013700016
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs4988235 0.0447506140350877 0.0181499122807018 0.0136779984517354
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs6087577 0.0499626925099214 0.0200226681182407 0.012584839777825
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs62081186 -0.0438272242148543 0.0217755227014259 0.0441479896225185
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs6510177 -0.0382122527885604 0.0180776961197969 0.0345341551326601
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs9354833 -0.0491195859406284 0.0220534428247838 0.025927373673808
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs9870005 -0.048802844133424 0.0210106280427413 0.0201915431468515
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0043351528097802 0.0018091078898138 0.016561839366324
Poultry (ukb-b-16010) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs34010017 0.016140654455976 0.0075526759669001 0.0325916823905942
Poultry (ukb-b-16010) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs62157712 -0.0296921670453726 0.0081954122837298 0.0002911799405799
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs10087278 0.0586108860917248 0.0207990982409913 0.0048330849196528
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs17184707 -0.0387161329241745 0.0196172441227127 0.0484299126500635
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs3757323 -0.051539914124497 0.0214405503225952 0.0162233308462781
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs4808846 -0.0426430305996303 0.0213348517565853 0.045635432205744
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs536421612 -0.0408276417866708 0.0203802414463991 0.045145602286897
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs565226 -0.0491124809800632 0.0224742694393508 0.0288686181047947
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs58563230 -0.0693011000907456 0.0229985034944995 0.0025843407164376
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs62084586 -0.0385550147074194 0.0185529989697341 0.0377000129378224
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs72720396 0.0544030980615237 0.0191019122215902 0.0043988758630509
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs907237 0.057410535977561 0.0229698416489616 0.0124408179163802
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0046899387956327 0.0018661785635818 0.0119667145091069
Dried fruit (ukb-b-16576) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - MR Egger -0.0241704598686675 0.0085065374810807 0.0051729566905317
Grapefruit (ukb-b-18758) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs13027142 0.116894975423196 0.0273808659038108 1.96156593829593e-05
Grapefruit (ukb-b-18758) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - MR Egger -0.401714651265386 0.0906098121407329 0.0213262635073502
Cherry (ukb-b-2221) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted 0.0190068123287873 0.009371636051138 0.0425478952332874
Lettuce (ukb-b-2867) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0059174259173563 0.0029450287869034 0.0445060629584787
Danish pastry (ukb-b-447) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs34599940 -0.0616653831499931 0.0251878663089033 0.0143564834893479
Danish pastry (ukb-b-447) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0299346729236207 0.0146396615100415 0.0408779951358884
Milk chocolate (ukb-b-4569) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs13036311 0.0339941619322394 0.0113607188703466 0.0027692531635187
Milk chocolate (ukb-b-4569) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs4708314 0.032418472916093 0.011259391841391 0.0039863691451781
Milk chocolate (ukb-b-4569) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted 0.0185979845338805 0.0052582211334692 0.0004047998115837
Lamb (ukb-b-530) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0164498181937566 0.0066755952843003 0.0137330008032134
Other grain (ukb-b-8765) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0544815107741291 0.0243144529581302 0.0250452047937423
Fortified wine (ukb-b-9524) Operative procedures - secondary OPCS: Z81.4 Shoulder joint rs4279116 -0.054845085402979 0.0258200765744451 0.0336596431596159
Fortified wine (ukb-b-9524) Operative procedures - secondary OPCS: Z81.4 Shoulder joint All - Inverse variance weighted -0.0251017614844677 0.0126840328441429 0.0478154693677273