ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC (ukb-b-13151)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Mixed vegetable (ukb-b-13155) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Inverse variance weighted 2 0.006547663 0.003086508 0.033889647
Vegetarian alternatives (ukb-b-14425) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Inverse variance weighted 3 -0.027567238 0.012539433 0.027917503
Indian snacks (ukb-b-282) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Wald ratio 1 0.033332839 0.014004272 0.017303682
Other bread (ukb-b-4964) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Wald ratio 1 -0.014380657 0.006743833 0.032972663
White fish (ukb-b-5427) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Inverse variance weighted 2 0.022382883 0.008237508 0.006583857
Processed meat (ukb-b-6324) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Weighted median 62 0.003816759 0.00175691 0.029823486
Courgette (ukb-b-7420) (👉 📊) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC Inverse variance weighted 2 -0.009504596 0.004435778 0.03213619

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Mixed vegetable (ukb-b-13155) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC All - Inverse variance weighted 0.0065476634462869 0.0030865080667619 0.0338896472399115
Vegetarian alternatives (ukb-b-14425) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC All - Inverse variance weighted -0.0275672383020514 0.0125394334000179 0.0279175027722699
Indian snacks (ukb-b-282) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs12784972 0.0333328388321861 0.0140042724899122 0.017303681656888
Other bread (ukb-b-4964) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs7844293 -0.0143806567554321 0.006743832707074 0.0329726633430799
White fish (ukb-b-5427) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs11098631 0.0308016990594492 0.0101777587406971 0.0024750638411601
White fish (ukb-b-5427) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC All - Inverse variance weighted 0.0223828830941513 0.0082375077439082 0.006583857223022
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs12788387 0.0253340534848677 0.010979829705343 0.0210366179708822
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs2873054 -0.0244815587533403 0.0082462595921633 0.0029895764708149
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs4813338 0.0225620136420405 0.0105913152079931 0.0331520353896748
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC rs6786550 0.0270020759655702 0.0094016624135356 0.0040781412239258
Courgette (ukb-b-7420) Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC All - Inverse variance weighted -0.0095045964467269 0.0044357777322814 0.0321361900833591