ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach (ukb-b-13920)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sponge pudding (ukb-b-12067) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Weighted median 7 0.027742515 0.01200553 0.020843279
Vegetable pieces (ukb-b-12566) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 5 -0.007464642 0.003187309 0.019181272
Snackpot (ukb-b-12912) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 2 -0.14072371 0.071216081 0.04815361
Other sweets (ukb-b-139) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Weighted median 10 0.014433587 0.00568128 0.01106777
Other sweets (ukb-b-139) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 10 0.012242327 0.004306538 0.004472886
Lamb/mutton (ukb-b-14179) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach MR Egger 104 -0.031183158 0.012606165 0.015025413
Water (ukb-b-14898) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 134 -0.003254415 0.001616898 0.044140761
Beef (ukb-b-2862) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 78 -0.005342902 0.002398153 0.025885614
Milk (ukb-b-2966) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach MR Egger 11 0.078921593 0.032294984 0.037134134
Wholemeal pasta (ukb-b-4150) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Weighted median 7 0.024200014 0.011684997 0.038355717
Wholemeal pasta (ukb-b-4150) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 7 0.019281235 0.008810502 0.028637731
Baguette (ukb-b-5277) (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach Inverse variance weighted 3 0.012722691 0.005825992 0.028978337

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sponge pudding (ukb-b-12067) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs61677937 0.0475168679716785 0.0230325825777721 0.0391099465283995
Vegetable pieces (ukb-b-12566) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted -0.0074646420125716 0.0031873085116742 0.0191812715580384
Snackpot (ukb-b-12912) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted -0.140723710265543 0.071216081019781 0.0481536096228981
Other sweets (ukb-b-139) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs963422 0.0327412044882586 0.0144538028026281 0.0234984979313208
Other sweets (ukb-b-139) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted 0.0122423266560198 0.0043065377016212 0.0044728855670682
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs11090045 -0.0600783057483538 0.0182837365704705 0.0010166151905858
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs11756299 -0.0777619657323465 0.0237277139349927 0.0010481857937868
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs1711171 -0.0546981321979448 0.0233576360410139 0.0191927125114977
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs2396885 -0.0536923774150008 0.0238563166865351 0.0244072934160034
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs2926119 0.059099073997591 0.0222035923123677 0.0077749505589749
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs4486004 -0.0676038935564884 0.0246673208847821 0.006132232083265
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs4861436 0.0516197260156982 0.0243734203734791 0.0341861129780953
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs6500598 -0.0482165446676036 0.0244160765053724 0.0482923519319664
Lamb/mutton (ukb-b-14179) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - MR Egger -0.0311831581456045 0.012606165497542 0.0150254129270424
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs11890994 -0.0379867864836363 0.0166286605316052 0.0223470647986411
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs12692772 -0.0512217344096681 0.0181904627025715 0.0048647375618431
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs1313237 -0.0463944769266343 0.0188061556502494 0.013625661100359
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs2917704 -0.0522236979281553 0.0211730778607733 0.0136435305599247
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs58959216 -0.0376628146271965 0.0187918315656166 0.0450473539468323
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs7626335 -0.040411834077761 0.0176176768286455 0.021800661989932
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs9419447 -0.0474278087974942 0.0196389486585864 0.0157357644995517
Water (ukb-b-14898) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted -0.0032544146706158 0.0016168982585222 0.0441407605859006
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs132901 -0.040600363377834 0.0156235233287133 0.0093586006674568
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs35800274 0.0535424488721618 0.022018883162401 0.0150297868957982
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs4916505 -0.0519053210072321 0.0206662672451762 0.0120186478426491
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs62396185 -0.0312559364621717 0.0136678410476466 0.0222061427961155
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs784251 -0.0343838200160562 0.0172617447067813 0.0463810726900786
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs803370 -0.0404354486321105 0.0204112789217739 0.0475873998139384
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach rs9319848 0.0446040349132222 0.022717103968427 0.0495932081047413
Beef (ukb-b-2862) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted -0.0053429020512361 0.0023981532368752 0.0258856140661621
Milk (ukb-b-2966) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - MR Egger 0.0789215934409642 0.0322949840515033 0.0371341336607048
Wholemeal pasta (ukb-b-4150) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted 0.0192812354116638 0.0088105021231693 0.0286377312814815
Baguette (ukb-b-5277) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach All - Inverse variance weighted 0.0127226908874825 0.00582599185554 0.0289783372367616