ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Crisp (ukb-b-12602) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 6 -0.012850465 0.004622187 0.005433049
Crisp (ukb-b-12602) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 6 -0.011757315 0.00349055 0.000756257
Homemade soup (ukb-b-12658) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 7 0.014152831 0.00686975 0.039382583
Homemade soup (ukb-b-12658) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 7 0.018133887 0.004961935 0.000257584
Red wine (ukb-b-13556) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 6 0.005098746 0.002342146 0.029483934
Celery (ukb-b-14145) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 5 -0.012575014 0.006108303 0.039525338
Cheese (ukb-b-1489) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC MR Egger 172 0.012520177 0.005837564 0.033392082
Cereal (ukb-b-15926) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 148 -0.003464703 0.001619151 0.032368806
Fruit smoothie (ukb-b-1780) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 4 -0.022475052 0.010389514 0.030522436
Plain cereal (ukb-b-20023) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 5 0.017847631 0.008269176 0.030901986
Orange juice (ukb-b-2763) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 5 -0.008248801 0.004177233 0.048301691
Orange juice (ukb-b-2763) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 5 -0.007581063 0.003434964 0.027312075
Cake (ukb-b-3433) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 4 -0.012491366 0.005079019 0.013916753
Hard cheese (ukb-b-3542) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 3 0.012585494 0.004758981 0.008179292
Sushi (ukb-b-5213) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 2 0.086899215 0.036899803 0.018522463
Baguette (ukb-b-5277) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 3 0.018472917 0.006724589 0.00601303
Processed meat (ukb-b-6324) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC MR Egger 107 -0.022497856 0.009091575 0.014940153
Filtered coffee (ukb-b-748) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 16 -0.003473059 0.001745957 0.046679058
Poultry (ukb-b-8006) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Weighted median 64 0.007833006 0.003683557 0.033463437
Cooked vegetable (ukb-b-8089) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC MR Egger 78 -0.038777417 0.017871723 0.033150062
Sweet potato (ukb-b-9686) (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC Inverse variance weighted 5 0.020793872 0.009102586 0.022348514

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Crisp (ukb-b-12602) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs12959170 -0.0179105532071023 0.007567106562528 0.0179379793789744
Crisp (ukb-b-12602) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted -0.0117573145354537 0.0034905497133748 0.0007562570887718
Homemade soup (ukb-b-12658) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs1174972 0.0321250266461878 0.0134920444048471 0.0172640830359605
Homemade soup (ukb-b-12658) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs4660057 0.0333291754513223 0.0127711831660012 0.009061711921467
Homemade soup (ukb-b-12658) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0181338869142115 0.0049619354850111 0.0002575837606522
Red wine (ukb-b-13556) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0050987460541728 0.0023421459458732 0.0294839338495482
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs10896050 0.0338869487533501 0.0125228078724383 0.0068095269070012
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs1473677 -0.0427323196411967 0.0177949461248154 0.0163336363524763
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs1931805 -0.0404775131961096 0.0144468713151793 0.0050815433000602
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs2802530 0.047935371994889 0.0148869358873869 0.0012820746574848
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs59784053 0.0474808320662547 0.0171423603248035 0.0056091502122728
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs67238148 -0.0268633637990232 0.0133905773973596 0.0448413860300832
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs7515509 -0.0384446770019551 0.0151343830871198 0.011078245766585
Cheese (ukb-b-1489) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - MR Egger 0.012520176687494 0.0058375635454364 0.033392082315444
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs11097340 -0.034036710770458 0.0161053982346923 0.0345688710388989
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs12887676 0.0507457189312049 0.0221901964917892 0.0222044007506515
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs17599026 -0.0499445314539285 0.0222206995562516 0.0245980108900995
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs2799849 -0.0373691894654024 0.0158277705229177 0.0182262794102901
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs616243 -0.045591953817 0.0214705164832751 0.0337146576780051
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs6918737 -0.0324158747496814 0.0157265610777353 0.039282222917409
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs72702504 0.0780662515337019 0.0203863282681844 0.0001284856151966
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs9987289 -0.0345241466540556 0.0169107169840888 0.0411957642977112
Cereal (ukb-b-15926) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted -0.0034647029777914 0.0016191514936481 0.0323688055398321
Fruit smoothie (ukb-b-1780) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted -0.0224750521062785 0.0103895143624442 0.0305224362176692
Plain cereal (ukb-b-20023) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs12926199 0.0292787604769837 0.0122263292879617 0.0166325972035755
Plain cereal (ukb-b-20023) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs7692440 0.02769506205853 0.0125630857731717 0.0274906567928698
Orange juice (ukb-b-2763) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted -0.0075810627865609 0.0034349638599751 0.0273120753981664
Cake (ukb-b-3433) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs4233064 -0.0201488290855606 0.0096049456484269 0.0359267353439902
Cake (ukb-b-3433) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted -0.012491365567166 0.0050790193557072 0.0139167526501941
Hard cheese (ukb-b-3542) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs12703042 0.0196313432416937 0.0082595552062994 0.0174633681974079
Hard cheese (ukb-b-3542) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0125854939616772 0.0047589805772029 0.0081792922827361
Sushi (ukb-b-5213) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs61905205 0.100093048098873 0.0493773831652886 0.0426518665752583
Sushi (ukb-b-5213) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0868992150410681 0.0368998027026806 0.0185224629796766
Baguette (ukb-b-5277) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs966881 0.0312361296282688 0.0107471891829472 0.0036555948757022
Baguette (ukb-b-5277) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0184729172459246 0.0067245891712303 0.0060130297381453
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs4778053 -0.0321176070493784 0.0153325195697984 0.0361943143726948
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs62504693 -0.0407768235556547 0.0188171285969217 0.0302344250556053
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs9365786 0.0414769504982581 0.018833166797195 0.0276416232566068
Processed meat (ukb-b-6324) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - MR Egger -0.0224978559451562 0.009091574816872 0.0149401530420546
Poultry (ukb-b-8006) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs13405357 0.0420283282388103 0.0204843372623825 0.0401959145146365
Poultry (ukb-b-8006) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs77779142 -0.0418021696299286 0.0193768841835402 0.0309806198058834
Cooked vegetable (ukb-b-8089) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs10129582 0.0604764946108231 0.0215794344161414 0.0050707271866524
Cooked vegetable (ukb-b-8089) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC rs62291414 0.0555309577662565 0.0253138314538132 0.0282569676245645
Cooked vegetable (ukb-b-8089) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - MR Egger -0.0387774171437499 0.0178717227037357 0.0331500617520671
Sweet potato (ukb-b-9686) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC All - Inverse variance weighted 0.0207938722208715 0.0091025856856431 0.0223485142718886