ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fracture resulting from simple fall (ukb-b-15251)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Tinned tomato (ukb-b-10565) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 9 0.129528222 0.055057177 0.018642032
Pineapple (ukb-b-1164) (👉 📊) Fracture resulting from simple fall Weighted median 16 0.288547301 0.114048577 0.011404998
White rice (ukb-b-14690) (👉 📊) Fracture resulting from simple fall Weighted median 10 0.177886848 0.089320494 0.046419695
White rice (ukb-b-14690) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 10 0.202761895 0.066315115 0.002231531
Broad bean (ukb-b-15212) (👉 📊) Fracture resulting from simple fall MR Egger 13 0.656982375 0.219453282 0.012216127
Sprouts (ukb-b-16077) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 11 0.174748106 0.08897478 0.049527957
Fruitcake (ukb-b-17775) (👉 📊) Fracture resulting from simple fall Weighted median 15 -0.211206365 0.107457057 0.049356913
Plain cereal (ukb-b-20023) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 10 -0.156896898 0.070017524 0.025037524
Orange juice (ukb-b-2763) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 12 -0.076723898 0.039038651 0.049375858
Beef (ukb-b-2862) (👉 📊) Fracture resulting from simple fall MR Egger 99 0.326947786 0.13366784 0.016248056
Beef (ukb-b-2862) (👉 📊) Fracture resulting from simple fall Weighted median 99 0.128320027 0.053939778 0.017362037
Beef (ukb-b-2862) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 99 0.076908232 0.038987355 0.048535962
Porridge (ukb-b-29) (👉 📊) Fracture resulting from simple fall Weighted median 12 -0.13412658 0.062802253 0.032704123
White wine (ukb-b-311) (👉 📊) Fracture resulting from simple fall MR Egger 14 0.161275383 0.073612217 0.048930806
Hard cheese (ukb-b-3542) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 13 -0.101870068 0.039637776 0.010169123
Drinking water (ukb-b-3975) (👉 📊) Fracture resulting from simple fall Weighted median 21 0.048899164 0.017995246 0.006580938
Coffee (ukb-b-5237) (👉 📊) Fracture resulting from simple fall MR Egger 117 -0.173969779 0.062510236 0.006296591
Coffee (ukb-b-5237) (👉 📊) Fracture resulting from simple fall Weighted median 117 -0.111180137 0.049082115 0.023501246
Tea (ukb-b-6066) (👉 📊) Fracture resulting from simple fall Weighted median 139 -0.087512476 0.039867967 0.028159478
Watercress (ukb-b-6181) (👉 📊) Fracture resulting from simple fall MR Egger 7 -0.878755996 0.302912225 0.033750386
Watercress (ukb-b-6181) (👉 📊) Fracture resulting from simple fall Weighted median 7 -0.293648982 0.147085925 0.04588549
Pancake (ukb-b-6500) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 25 -0.271849111 0.118351553 0.021620894
Fresh tomato (ukb-b-730) (👉 📊) Fracture resulting from simple fall MR Egger 10 -0.304695507 0.128901624 0.045687614
Fresh tomato (ukb-b-730) (👉 📊) Fracture resulting from simple fall Weighted median 10 -0.075958498 0.037285472 0.041628568
Cooked vegetable (ukb-b-8089) (👉 📊) Fracture resulting from simple fall MR Egger 92 -0.374695644 0.164659367 0.025244825
Other grain (ukb-b-8765) (👉 📊) Fracture resulting from simple fall MR Egger 37 -0.605787236 0.294148426 0.04694948
Squash (ukb-b-8793) (👉 📊) Fracture resulting from simple fall MR Egger 18 0.201227567 0.080980126 0.024403858
Squash (ukb-b-8793) (👉 📊) Fracture resulting from simple fall Weighted median 18 0.095920643 0.044070612 0.029516272
Squash (ukb-b-8793) (👉 📊) Fracture resulting from simple fall Inverse variance weighted 18 0.070075852 0.034461088 0.042004292

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Tinned tomato (ukb-b-10565) Fracture resulting from simple fall All - Inverse variance weighted 0.129528222082342 0.0550571767558728 0.0186420316152256
White rice (ukb-b-14690) Fracture resulting from simple fall rs56338899 0.579504602529714 0.209290955420363 0.0056246822804004
White rice (ukb-b-14690) Fracture resulting from simple fall All - Inverse variance weighted 0.202761894861536 0.0663151145279494 0.0022315310192665
Broad bean (ukb-b-15212) Fracture resulting from simple fall rs184217006 0.789954655072489 0.297566047524262 0.0079374169869001
Broad bean (ukb-b-15212) Fracture resulting from simple fall rs186366228 0.603251932061223 0.304984926924202 0.0479317596167638
Broad bean (ukb-b-15212) Fracture resulting from simple fall rs7844716 -0.723923480560261 0.306494236251704 0.0181791867869652
Broad bean (ukb-b-15212) Fracture resulting from simple fall All - MR Egger 0.65698237493454 0.219453282290585 0.0122161268211879
Sprouts (ukb-b-16077) Fracture resulting from simple fall rs1430633 0.74978482856226 0.280219038763772 0.0074571183473738
Sprouts (ukb-b-16077) Fracture resulting from simple fall rs2148815 0.591149325863205 0.277174577226159 0.0329436863827661
Sprouts (ukb-b-16077) Fracture resulting from simple fall All - Inverse variance weighted 0.174748105988873 0.0889747801861 0.0495279573934426
Plain cereal (ukb-b-20023) Fracture resulting from simple fall All - Inverse variance weighted -0.156896897905557 0.0700175240484287 0.0250375243462832
Orange juice (ukb-b-2763) Fracture resulting from simple fall All - Inverse variance weighted -0.0767238981638216 0.0390386507477396 0.0493758579393974
Beef (ukb-b-2862) Fracture resulting from simple fall rs115736207 0.925522939617905 0.377276530469948 0.0141603949357364
Beef (ukb-b-2862) Fracture resulting from simple fall rs13145306 -0.932989506106515 0.38807946229242 0.0162114611330104
Beef (ukb-b-2862) Fracture resulting from simple fall rs140748046 1.01879943100996 0.409486960644855 0.0128467373653231
Beef (ukb-b-2862) Fracture resulting from simple fall rs4714375 0.77135797819421 0.392151413088238 0.0491843430244199
Beef (ukb-b-2862) Fracture resulting from simple fall rs62015188 0.80972776485056 0.361248086034988 0.0249954644289557
Beef (ukb-b-2862) Fracture resulting from simple fall rs952645 -1.28091893957259 0.406400496342375 0.0016223202699257
Beef (ukb-b-2862) Fracture resulting from simple fall rs9861346 -0.903498443523283 0.36882691656317 0.0142993426753818
Beef (ukb-b-2862) Fracture resulting from simple fall All - Inverse variance weighted 0.0769082324842787 0.0389873554128954 0.0485359615438457
Beef (ukb-b-2862) Fracture resulting from simple fall All - MR Egger 0.326947785715439 0.133667840164525 0.016248055828716
White wine (ukb-b-311) Fracture resulting from simple fall rs1229984 0.256692190730259 0.117452658033423 0.0288525759869625
White wine (ukb-b-311) Fracture resulting from simple fall All - MR Egger 0.161275383007889 0.0736122172589629 0.0489308061440333
Hard cheese (ukb-b-3542) Fracture resulting from simple fall rs760916 -0.407321866435886 0.149070207702293 0.0062871642616259
Hard cheese (ukb-b-3542) Fracture resulting from simple fall rs78213935 -0.342929900127799 0.140855398305486 0.0149072808444974
Hard cheese (ukb-b-3542) Fracture resulting from simple fall All - Inverse variance weighted -0.101870068171382 0.0396377762668833 0.0101691233699477
Drinking water (ukb-b-3975) Fracture resulting from simple fall rs12561532 0.12731977313809 0.0581738900822849 0.0286254290063038
Drinking water (ukb-b-3975) Fracture resulting from simple fall rs13162251 -0.144676821443401 0.0621076641821472 0.0198351339818485
Drinking water (ukb-b-3975) Fracture resulting from simple fall rs1504260 0.134007772695422 0.0577893141984786 0.0204003352582687
Coffee (ukb-b-5237) Fracture resulting from simple fall rs10938398 1.02217337944588 0.430899660006409 0.0176832709157155
Coffee (ukb-b-5237) Fracture resulting from simple fall rs13378240 -0.824342024995338 0.404692898957415 0.0416543533508268
Coffee (ukb-b-5237) Fracture resulting from simple fall rs4984636 -0.972660945782174 0.418926660872333 0.0202440898841535
Coffee (ukb-b-5237) Fracture resulting from simple fall rs6969878 -1.07474282090262 0.363459583477117 0.0031066798606737
Coffee (ukb-b-5237) Fracture resulting from simple fall rs7743687 -1.38466991224608 0.404158798685173 0.0006124183722093
Coffee (ukb-b-5237) Fracture resulting from simple fall All - MR Egger -0.173969778679914 0.0625102363297495 0.0062965913520596
Tea (ukb-b-6066) Fracture resulting from simple fall rs12446615 0.571958642759005 0.278439625036957 0.0399605202787367
Tea (ukb-b-6066) Fracture resulting from simple fall rs12591786 0.535113530984441 0.241312046160771 0.0265877921976627
Tea (ukb-b-6066) Fracture resulting from simple fall rs41135 0.703711595354974 0.33001360399269 0.0329763204928303
Tea (ukb-b-6066) Fracture resulting from simple fall rs56348300 -0.525955774945852 0.260975671183196 0.0438686088804837
Tea (ukb-b-6066) Fracture resulting from simple fall rs6829 -0.61975697154318 0.274582714433171 0.0240026626144463
Tea (ukb-b-6066) Fracture resulting from simple fall rs72797284 -0.491018247471472 0.210289984633093 0.019545623494522
Tea (ukb-b-6066) Fracture resulting from simple fall rs9478663 0.971613159068753 0.321259562796385 0.0024913774292027
Watercress (ukb-b-6181) Fracture resulting from simple fall rs116023894 -0.686354498756628 0.276448748731868 0.0130370738619312
Watercress (ukb-b-6181) Fracture resulting from simple fall All - MR Egger -0.878755996264188 0.302912225024604 0.0337503857453221
Pancake (ukb-b-6500) Fracture resulting from simple fall rs138627963 -1.4349888495343 0.616644365735275 0.0199603106051775
Pancake (ukb-b-6500) Fracture resulting from simple fall rs1549469 -1.33332762012497 0.611659896514752 0.0292684859028228
Pancake (ukb-b-6500) Fracture resulting from simple fall All - Inverse variance weighted -0.271849111193001 0.118351553227423 0.0216208938155956
Fresh tomato (ukb-b-730) Fracture resulting from simple fall rs11785751 0.247329736701052 0.086495788982969 0.0042438632174619
Fresh tomato (ukb-b-730) Fracture resulting from simple fall All - MR Egger -0.304695506817921 0.128901624046721 0.0456876141873255
Cooked vegetable (ukb-b-8089) Fracture resulting from simple fall rs111765914 -1.03769992102796 0.423264275855961 0.0142199114276925
Cooked vegetable (ukb-b-8089) Fracture resulting from simple fall rs1534749 1.08543391046435 0.435529645033105 0.0126948841030106
Cooked vegetable (ukb-b-8089) Fracture resulting from simple fall rs34299746 -1.27354681608714 0.425729210305823 0.0027765777618226
Cooked vegetable (ukb-b-8089) Fracture resulting from simple fall All - MR Egger -0.374695644057016 0.164659367462482 0.0252448247711072
Other grain (ukb-b-8765) Fracture resulting from simple fall rs10886080 2.26094295692666 0.94151144741948 0.0163325972421096
Other grain (ukb-b-8765) Fracture resulting from simple fall rs138677842 -1.50842814003679 0.57324275541809 0.0085035130369734
Other grain (ukb-b-8765) Fracture resulting from simple fall rs80164614 -2.01732146733232 0.964636422834817 0.0365032865176977
Other grain (ukb-b-8765) Fracture resulting from simple fall All - MR Egger -0.605787236025529 0.294148425521517 0.0469494803959279
Squash (ukb-b-8793) Fracture resulting from simple fall rs16850360 0.322201331065151 0.141259289103769 0.0225531002208622
Squash (ukb-b-8793) Fracture resulting from simple fall rs2424181 -0.276518533844411 0.138366255771409 0.0456675119371145
Squash (ukb-b-8793) Fracture resulting from simple fall All - Inverse variance weighted 0.0700758515092048 0.0344610880556768 0.0420042918343869
Squash (ukb-b-8793) Fracture resulting from simple fall All - MR Egger 0.201227567234697 0.08098012612064 0.0244038579669256