ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Bread (ukb-b-11348) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 88 -0.003773306 0.001687316 0.025333642
Grapefruit juice (ukb-b-14351) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Weighted median 6 -0.021128925 0.009939387 0.03352179
Grapefruit juice (ukb-b-14351) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 6 -0.017356163 0.008328639 0.037168038
Cheese (ukb-b-1489) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 158 -0.002535366 0.001099582 0.021124388
Cereal (ukb-b-15926) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Weighted median 138 -0.00546156 0.001998037 0.006267224
Cereal (ukb-b-15926) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 138 -0.005236709 0.001355284 0.000111582
Fruitcake (ukb-b-17775) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 4 -0.015106847 0.007007568 0.031100048
Oily fish (ukb-b-2209) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint MR Egger 148 0.012460691 0.005798605 0.033290121
Spirits (ukb-b-3751) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 3 0.009382809 0.004486442 0.036494929
Baked bean (ukb-b-4058) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Weighted median 4 -0.013192635 0.005659426 0.01974859
Coffee (ukb-b-5237) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint MR Egger 95 0.008005222 0.003307096 0.017436361
Pork (ukb-b-5640) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Weighted median 61 0.008175151 0.003769469 0.030099338
Processed meat (ukb-b-6324) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint MR Egger 89 -0.023768317 0.010073537 0.02053871
Other meat (ukb-b-770) (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint Inverse variance weighted 2 -0.036829084 0.016627702 0.026765332

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs10761661 -0.0312550064430746 0.0136144777626859 0.0216919904796111
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs10966045 0.0326708063639074 0.0158127664053044 0.0388187415744102
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs198167 0.0330990351684423 0.0160443803542459 0.0391157164544894
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs1994315 -0.0239747620944014 0.0099457914038956 0.0159287748771341
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs379336 0.0352348996807189 0.0164090573080774 0.0317707104935779
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4665972 -0.0251241561944634 0.0112003989856773 0.0248872514629545
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs591776 -0.0338760217983651 0.0157280070066174 0.0312506707298905
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs61878484 -0.037789481697822 0.015627270902686 0.0155985567911264
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs73802707 -0.0425444455604661 0.0135216201285657 0.0016529293924379
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint rs904512 -0.0302915496594687 0.0151337916787709 0.0453295312344409
Bread (ukb-b-11348) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0037733061536824 0.0016873162051344 0.0253336424645938
Grapefruit juice (ukb-b-14351) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0173561631333555 0.0083286390185635 0.0371680378231156
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs12296440 -0.0229350012237818 0.0110128656713241 0.0372909533703159
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs1519043 -0.0288720260679373 0.0140455296165692 0.0398208447524858
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs221418 0.0319121999962293 0.0151952263343451 0.0357159640544476
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2352974 -0.0257923599039815 0.0107437298236901 0.0163642131453414
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2644109 -0.0293163817143468 0.0146455395087357 0.0453140285044626
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4296548 -0.0254934162539829 0.0122000844562171 0.0366528639143257
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs531358 -0.0328967235277141 0.0123337080187748 0.0076481389018428
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs67967503 -0.0325164062573138 0.0149302090452073 0.0294139614430482
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7012814 -0.0236214429604506 0.008452265865922 0.0051949882751653
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs73096946 -0.0230863855784454 0.0103442213739717 0.0256272107289711
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7936836 -0.0267048148450911 0.0099234101956247 0.0071218443165706
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs9504123 -0.0258258648187092 0.0122728748253426 0.0353519002021596
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint rs9649582 -0.0303277095904656 0.0114558105168097 0.0081121788730509
Cheese (ukb-b-1489) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0025353663211771 0.0010995823659253 0.0211243878503331
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs10812904 -0.0351788265600095 0.0174572985364889 0.0438904262146182
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs112780312 -0.0284894182725155 0.0144749471119416 0.0490464019989939
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2302316 0.0348370968033068 0.0167562859876176 0.0376130818255057
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2875243 -0.04234837185089 0.0189810541585508 0.0256754062265537
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs834233 -0.0459057114642103 0.0163144219327996 0.0048957895407435
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint rs9569600 -0.0391843683497775 0.0188446508028632 0.0375864417603133
Cereal (ukb-b-15926) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0052367093031321 0.0013552839501411 0.0001115815959429
Fruitcake (ukb-b-17775) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0151068471281944 0.0070075681999081 0.0311000479727209
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs1201289 0.0329318976366942 0.0148281359250454 0.0263573214942409
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs1260326 -0.0454722927033815 0.0169549144028309 0.007319362411713
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs16850013 -0.0440713796715578 0.0171092635208143 0.009998584760858
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs321243 -0.0324860380528692 0.0151020057470716 0.031467714495205
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4419275 -0.0322502115600338 0.0156473737035798 0.0392970997905386
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4982738 -0.044033404537419 0.0147100581909252 0.002758684606049
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs55871839 0.0340026706726757 0.0155405657505867 0.0286700109969732
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7147583 -0.0345479227069332 0.0174770819018251 0.0480692420626018
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7683782 -0.0423609739250561 0.0144321188050423 0.0033334625067196
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs8182438 -0.035486264943125 0.0153754124255765 0.02099981272356
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs905575 0.031354088630208 0.0147287932922261 0.0332739947549069
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint rs9597870 0.0291784949273827 0.0141990914012664 0.0398833441696703
Oily fish (ukb-b-2209) Operative procedures - secondary OPCS: Z84.3 Hip joint All - MR Egger 0.0124606913133169 0.0057986046433783 0.0332901214111259
Spirits (ukb-b-3751) Operative procedures - secondary OPCS: Z84.3 Hip joint rs62001190 0.0150179889598441 0.0073968611321571 0.0423241067903527
Spirits (ukb-b-3751) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted 0.0093828088828294 0.0044864418408105 0.0364949290468962
Baked bean (ukb-b-4058) Operative procedures - secondary OPCS: Z84.3 Hip joint rs12540361 -0.0189157706751722 0.0080105681676208 0.0182084412669646
Baked bean (ukb-b-4058) Operative procedures - secondary OPCS: Z84.3 Hip joint rs9956645 -0.0226280697053701 0.0078634953677463 0.0040070069906688
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint rs13088645 -0.046425811512178 0.0204223307922444 0.0230089128001693
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2465037 0.0322499694310411 0.0154432499035902 0.0367717700066445
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint rs2521501 0.0404296744236272 0.0180597159980563 0.0251776482478867
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint rs780093 0.0285516981983676 0.0119829992101403 0.0171869494208488
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7811609 -0.0369256256948517 0.0175201124018454 0.0350644335272271
Coffee (ukb-b-5237) Operative procedures - secondary OPCS: Z84.3 Hip joint All - MR Egger 0.0080052221759319 0.0033070955312875 0.0174363608181721
Pork (ukb-b-5640) Operative procedures - secondary OPCS: Z84.3 Hip joint rs72932757 0.0511093621247016 0.0207613725200194 0.0138260012576721
Pork (ukb-b-5640) Operative procedures - secondary OPCS: Z84.3 Hip joint rs905112 -0.0596951485227817 0.0211651582021148 0.0047957207407291
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs12245149 -0.036414326453671 0.0150176422253371 0.0153180932967448
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4077924 -0.0297844575835887 0.013550849288326 0.0279507317643461
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs4965927 0.0321328236043719 0.0158663921972259 0.0428454982428429
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs6484504 -0.0232486040018613 0.0112469624114575 0.0387246650915563
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs6689819 0.0312052687757643 0.0159158916785546 0.049921510158405
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs715400 0.0295930322322831 0.0147491985069069 0.0448118511329008
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint rs7531118 -0.0230218378470569 0.011134814772703 0.0386819220421665
Processed meat (ukb-b-6324) Operative procedures - secondary OPCS: Z84.3 Hip joint All - MR Egger -0.0237683168659799 0.0100735374288021 0.0205387104137015
Other meat (ukb-b-770) Operative procedures - secondary OPCS: Z84.3 Hip joint All - Inverse variance weighted -0.0368290836533666 0.0166277018953999 0.0267653324214311