ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe (ukb-b-17501)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Salted peanuts (ukb-b-1099) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 4 0.012271964 0.0052784 0.020075157
Pineapple (ukb-b-1164) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 2 0.020566288 0.008282081 0.013019803
Vegetable pieces (ukb-b-12566) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 3 0.00602133 0.00271774 0.02672132
Low fat hard cheese (ukb-b-18079) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 3 0.012838562 0.006143987 0.036652482
Standard tea (ukb-b-3291) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Weighted median 7 2.32e-05 1.11e-05 0.036366023
Fresh fruit (ukb-b-3881) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 98 0.004451299 0.001668869 0.007647381
Green tea (ukb-b-4078) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe MR Egger 6 0.000130074 4.45e-05 0.043227461
Chocolate-covered biscuits (ukb-b-5068) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 2 0.007739937 0.003414541 0.023405014
Tofu (ukb-b-5522) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Wald ratio 1 -0.096167813 0.030169063 0.001434439
Tea (ukb-b-6066) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Weighted median 92 0.003452008 0.001544311 0.025397244
Berry (ukb-b-8887) (👉 📊) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe Inverse variance weighted 3 0.007410506 0.003223277 0.021501552

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Salted peanuts (ukb-b-1099) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0122719636201429 0.0052783996550958 0.0200751573142307
Pineapple (ukb-b-1164) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs1701827 0.0289177735901089 0.0123015121570069 0.0187356420782943
Pineapple (ukb-b-1164) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0205662880605225 0.0082820808171877 0.0130198029564182
Vegetable pieces (ukb-b-12566) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs585477 0.0113015908112782 0.0048409780982125 0.0195660187242514
Vegetable pieces (ukb-b-12566) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0060213299726425 0.0027177403766009 0.0267213203418013
Low fat hard cheese (ukb-b-18079) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0128385616713002 0.0061439869962565 0.0366524816327416
Standard tea (ukb-b-3291) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs4791937 6.11282023037704e-05 2.64174324919746e-05 0.0206713280691161
Fresh fruit (ukb-b-3881) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs12446517 0.0507408830715047 0.0192009173646447 0.0082265348528791
Fresh fruit (ukb-b-3881) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs2189620 0.0409713992662432 0.0199640222493984 0.0401442310506792
Fresh fruit (ukb-b-3881) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0044512986450666 0.0016688693034108 0.0076473807643112
Green tea (ukb-b-4078) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs12236847 -0.0004190985045188 0.0002121534997431 0.0482171710620982
Green tea (ukb-b-4078) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs9327186 7.98353247588758e-05 3.40912510441365e-05 0.0191903425933063
Green tea (ukb-b-4078) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - MR Egger 0.0001300740837704 4.45402685708091e-05 0.0432274609290666
Chocolate-covered biscuits (ukb-b-5068) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs9502103 0.0111156703453068 0.0049325766475289 0.0242262506708857
Chocolate-covered biscuits (ukb-b-5068) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.0077399371507247 0.0034145405853029 0.0234050137970577
Tofu (ukb-b-5522) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs6597123 -0.0961678128947469 0.0301690633253799 0.0014344393460931
Tea (ukb-b-6066) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs11715828 -0.0266186431670387 0.0114235054255926 0.0197974753110245
Tea (ukb-b-6066) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs17685 0.0113709219396935 0.0057046671435694 0.0462322720954845
Tea (ukb-b-6066) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe rs6129076 -0.028540139099711 0.0108015813801916 0.008236487969454
Berry (ukb-b-8887) Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe All - Inverse variance weighted 0.007410505659781 0.0032232767917377 0.0215015515183581