ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweets (ukb-b-10217) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 6 0.006311215 0.003100202 0.041776189
Sweetened cereal (ukb-b-10640) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 2 0.024519651 0.012473001 0.049319616
Plum (ukb-b-14182) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 2 0.011072612 0.005483633 0.043465279
Lobster/crab (ukb-b-14746) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 5 0.04622547 0.022021388 0.03580659
Cheese (ukb-b-1489) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 148 -0.002964689 0.00110928 0.007526034
Side salad (ukb-b-1604) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Weighted median 5 0.004595943 0.002305671 0.046226259
Mixed fruit (ukb-b-18956) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Weighted median 6 0.013782468 0.006341552 0.029753331
Plain cereal (ukb-b-20023) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 5 0.009997619 0.004448498 0.024613564
Oily fish (ukb-b-2209) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Weighted median 134 -0.005702395 0.001774362 0.001310034
Oily fish (ukb-b-2209) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 134 -0.003674737 0.00127346 0.003906287
Coleslaw (ukb-b-2691) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 4 0.011158973 0.004700514 0.017597015
Spirits (ukb-b-3751) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Weighted median 3 0.011108153 0.005107678 0.029645455
Spirits (ukb-b-3751) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 3 0.010053817 0.004148232 0.01536587
Seeds (ukb-b-4548) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 4 -0.023402011 0.009514401 0.013907604
Oat crunch (ukb-b-5186) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 2 -0.0247489 0.012231236 0.043030096
Garlic bread (ukb-b-602) (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy Inverse variance weighted 4 0.013496531 0.006789891 0.046840557

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweets (ukb-b-10217) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.00631121480632 0.0031002024405488 0.0417761885775828
Sweetened cereal (ukb-b-10640) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0245196514321922 0.0124730006138168 0.0493196163836308
Plum (ukb-b-14182) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0110726120110834 0.0054836325845993 0.0434652787957449
Lobster/crab (ukb-b-14746) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0462254700160722 0.0220213882747687 0.0358065901083151
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs11104660 -0.0309176631591245 0.0127288733863498 0.0151430596676735
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs113367286 -0.0231472954010949 0.0105751101800431 0.028607981524477
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs17207890 -0.0380184639627295 0.0129903740750891 0.0034261848888988
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2352974 -0.0272969263030102 0.0099337113373617 0.0059976808925507
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2824098 0.0431996256905829 0.0133593370404362 0.0012221255461658
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2838986 -0.0425446392556539 0.0124534783660957 0.0006348162198577
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2960578 -0.0302275049623566 0.0084266687025052 0.0003343454382949
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2968940 -0.0327076409253829 0.012550505050505 0.0091584626383169
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs4675530 0.0303445776664281 0.0131102362204724 0.0206364001374566
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs67238148 -0.0246457759079259 0.0105340562889888 0.0193029417510171
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs7439876 -0.0332813086984734 0.0124205969741471 0.0073726545276335
Cheese (ukb-b-1489) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted -0.0029646889029392 0.0011092798070401 0.0075260337800008
Mixed fruit (ukb-b-18956) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs381390 0.0251806159447545 0.01239735507846 0.0422420042453786
Plain cereal (ukb-b-20023) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs7692440 0.019454158867228 0.0098832530018327 0.0490224546583297
Plain cereal (ukb-b-20023) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0099976189746297 0.0044484984922064 0.0246135641105454
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs1053924 -0.0339981609563027 0.0123839603406229 0.0060448543679791
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs11777164 0.0309893181118401 0.0153820013325329 0.0439415450351065
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs13058717 -0.0332201215881056 0.0158071081270327 0.0355888670478422
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs13070166 0.0342127300235741 0.0120308926498012 0.0044587422918772
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs1876245 -0.0236253820404599 0.0095884547703788 0.0137418921379542
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs2591847 0.0370726739808155 0.0148632464534847 0.0126223092979162
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs3923087 0.0337716525122526 0.0161473493209622 0.0364861979411011
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs6089753 0.0271320395078842 0.0124682030843875 0.0295478872030559
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs7338243 -0.0384606368783584 0.0151142305889141 0.0109382966616463
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs905575 -0.0271571918400277 0.0136183224802628 0.0461339471515164
Oily fish (ukb-b-2209) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted -0.0036747368580996 0.0012734599940167 0.0039062866444501
Coleslaw (ukb-b-2691) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs10486318 0.0188113060662315 0.009529263229335 0.0483752944147124
Coleslaw (ukb-b-2691) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0111589734405439 0.0047005135794323 0.0175970148132735
Spirits (ukb-b-3751) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0100538172861251 0.0041482321133633 0.0153658700268293
Seeds (ukb-b-4548) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy rs1441393 -0.0448542026856092 0.0204107402272439 0.0279791609671172
Seeds (ukb-b-4548) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted -0.0234020112527743 0.0095144010045878 0.0139076036838098
Oat crunch (ukb-b-5186) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted -0.024748899665449 0.012231235858481 0.0430300963189418
Garlic bread (ukb-b-602) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy All - Inverse variance weighted 0.0134965310058549 0.0067898907212076 0.046840556509716