ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Beef (ukb-b-10829) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 5 0.009053869 0.004176469 0.03017172
Mixed vegetable (ukb-b-13155) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 3 0.007010243 0.003218738 0.029409947
Herbal tea (ukb-b-13344) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 4 0.000282529 0.000123464 0.022117796
Grapefruit juice (ukb-b-14351) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 5 0.016593187 0.007403326 0.025005662
Water (ukb-b-14898) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 120 -0.003016627 0.001300398 0.020353268
Water (ukb-b-14898) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted mode 120 -0.008088675 0.003450059 0.020709414
Canned soup (ukb-b-15094) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 2 -0.02555363 0.010712133 0.01705663
Cereal (ukb-b-15926) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 131 -0.002539185 0.001290759 0.04915983
Pea (ukb-b-15945) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 2 -0.007986997 0.003951825 0.043270381
Salted nuts (ukb-b-15960) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 4 -0.021069672 0.009315653 0.023712896
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 118 -0.003303074 0.001444985 0.022260752
Standard tea (ukb-b-3291) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 8 3.49e-05 1.23e-05 0.004655188
Standard tea (ukb-b-3291) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 8 2.02e-05 1e-05 0.04412411
Hard cheese (ukb-b-3542) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 3 0.008322795 0.003649344 0.022570494
Pizza (ukb-b-3852) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 2 -0.018210835 0.00601887 0.002481212
Drinking water (ukb-b-3975) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 12 -0.001653522 0.000692359 0.016929021
Beer/cider (ukb-b-4961) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 4 0.008132128 0.003307684 0.013949674
Coffee (ukb-b-5237) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon MR Egger 87 0.007056242 0.003092966 0.02502576
Coffee (ukb-b-5237) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 87 0.006505232 0.002483536 0.008809942
Coffee (ukb-b-5237) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 87 0.003589623 0.001459673 0.013924852
Coffee (ukb-b-5237) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted mode 87 0.006720113 0.002169434 0.00263481
Tofu (ukb-b-5522) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 2 0.069181888 0.025200355 0.006046033
Yorkshire pudding (ukb-b-5605) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 4 0.013307446 0.006609633 0.044078739
Tea (ukb-b-6066) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 107 0.006292451 0.001766638 0.00036829
Tea (ukb-b-6066) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Inverse variance weighted 107 0.00342939 0.001086129 0.001591587
Tea (ukb-b-6066) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted mode 107 0.005909775 0.00206445 0.005063935
Filtered coffee (ukb-b-748) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon MR Egger 13 0.023219416 0.0073715 0.009243994
Filtered coffee (ukb-b-748) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon Weighted median 13 0.004315796 0.001519783 0.004514955
Instant coffee (ukb-b-930) (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon MR Egger 9 0.026085594 0.006857838 0.006681941

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Mixed vegetable (ukb-b-13155) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2730078 0.0119624558162097 0.0056603760125266 0.0345693085961127
Mixed vegetable (ukb-b-13155) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0070102432453228 0.0032187384212544 0.0294099467904814
Herbal tea (ukb-b-13344) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs855736 0.0005339799858821 0.00025214964913 0.0341995842104209
Herbal tea (ukb-b-13344) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0002825285218256 0.0001234644607843 0.0221177959106939
Grapefruit juice (ukb-b-14351) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0165931868262991 0.0074033257231522 0.0250056619806554
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs11012726 -0.0404960338531668 0.0124815580299156 0.0011766963439616
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs12620738 0.0336615025587745 0.0150879051571957 0.0256794337478443
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 -0.0106802179617998 0.0047454269615514 0.0244087455230745
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2675638 -0.0329665528917292 0.0160359117275938 0.0398022456604713
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs34940743 -0.0326597832990127 0.0140955716787591 0.020502403465935
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs6747465 0.0339922102033782 0.0155183672480567 0.0284916047745966
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs6905712 -0.0312330780955473 0.0134172100615998 0.0199207602601587
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs7513076 0.0358691923265927 0.0154205775968731 0.0200153376008752
Water (ukb-b-14898) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0030166266751983 0.001300398473875 0.0203532683644667
Canned soup (ukb-b-15094) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs341745 -0.0364691442638543 0.0129617170671665 0.0048989474478941
Canned soup (ukb-b-15094) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0255536295008845 0.0107121328989901 0.0170566302742883
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs10809287 0.0309205790044165 0.01480271140375 0.0367216215459259
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs11678980 -0.0481331330994278 0.0162720352699005 0.0030961417461151
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs1455349 -0.0337325656032162 0.0167113694904115 0.0435350661570421
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2456141 0.0356922341749644 0.0163838015647226 0.0293682763448751
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 -0.0225159918747398 0.010004289733658 0.0244087455230745
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs62009152 0.0346612105582843 0.0168210392247114 0.0393424818467673
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs62377431 -0.0316473765711454 0.0152056776911054 0.0374076607988463
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs72753733 0.0349596666880799 0.0158389237108482 0.027300115027969
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs844137 -0.0390406313369114 0.0165309977873166 0.0181932150615424
Cereal (ukb-b-15926) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0025391847898282 0.0012907590041768 0.0491598297617059
Pea (ukb-b-15945) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0079869967322843 0.003951825063472 0.0432703808590536
Salted nuts (ukb-b-15960) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs9613266 -0.0438762128880436 0.0180311401953515 0.0149595164258808
Salted nuts (ukb-b-15960) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0210696718107675 0.0093156530063411 0.0237128959399072
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs10192800 -0.0370363031118126 0.0173170568695206 0.0324585051452385
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs10740991 -0.0184337176653325 0.0092903996654519 0.0472370673013534
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs1947897 0.0395304094554562 0.0180309311282586 0.0283530531848815
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs34819186 -0.0444273691184565 0.0174954980086628 0.0111055459322509
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs67518212 -0.0472319488817891 0.0156092195344592 0.0024789366995283
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs7742849 -0.0365637069309945 0.017535220981336 0.0370549577031427
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs9527691 -0.0357549985866976 0.0164577774602593 0.0298157856984922
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0033030743270532 0.0014449845505921 0.0222607516113863
Standard tea (ukb-b-3291) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2389763 5.76679614953854e-05 2.52364007542141e-05 0.0223063559042028
Standard tea (ukb-b-3291) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 3.49663482733284e-05 1.55362233651727e-05 0.0244087455230745
Standard tea (ukb-b-3291) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 2.02207288316087e-05 1.00455211333432e-05 0.0441241100216528
Hard cheese (ukb-b-3542) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0083227948339522 0.0036493441126824 0.0225704938208394
Pizza (ukb-b-3852) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs1480734 -0.017706101626261 0.0087942897492459 0.0440764068685972
Pizza (ukb-b-3852) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs17688422 -0.0186555837671456 0.0082551998373499 0.0238300324318496
Pizza (ukb-b-3852) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0182108345046227 0.006018870350889 0.0024812119800142
Drinking water (ukb-b-3975) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 -0.0036287966131679 0.0016123443685986 0.0244087455230745
Drinking water (ukb-b-3975) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted -0.0016535222203004 0.0006923585127546 0.0169290210791151
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs10938398 0.0382337884753209 0.0188163914939108 0.0421596769590386
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2372891 -0.0362307286212165 0.0179929867632668 0.0440512516843235
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 0.0076805004432891 0.0034125945755183 0.0244087455230745
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs4615895 -0.02620045072731 0.013139192788363 0.0461445668384213
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs71429826 0.0431580155425124 0.0186304663846717 0.0205294032742876
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs723145 0.0587085425652228 0.0177309202402778 0.0009293575147964
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs730632 0.039273789808311 0.0175398321055337 0.0251481057748887
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs8056750 0.0292561685321789 0.0142901085130016 0.0406284362123266
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0035896233687944 0.0014596734690949 0.0139248516258383
Coffee (ukb-b-5237) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - MR Egger 0.0070562422852178 0.0030929664644491 0.0250257595128674
Tofu (ukb-b-5522) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs6597123 0.0702172942212241 0.0357697166115882 0.0496418196072389
Tofu (ukb-b-5522) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0691818881353348 0.0252003547570542 0.0060460325726271
Yorkshire pudding (ukb-b-5605) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0133074461989648 0.0066096326447015 0.044078739249035
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs1285244 0.0325652768856991 0.0130739944334292 0.012744016278188
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs132904 0.0199578331034233 0.0101472227074762 0.0492031415853831
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs1394094 0.0446091753119832 0.0137047060592392 0.0011338196310117
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 0.0066907300174523 0.0029728204734062 0.0244087455230745
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs34940743 0.0285359845300151 0.0123157894736842 0.020502403465935
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs4451355 -0.0363371947445279 0.0144287107907847 0.0117890990050589
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs62092408 0.0314118639071508 0.0123473479992596 0.0109585733456442
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs9438548 0.0303415711186861 0.0125816547877285 0.0158838989692723
Tea (ukb-b-6066) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - Inverse variance weighted 0.0034293902561558 0.0010861285654302 0.0015915873619733
Filtered coffee (ukb-b-748) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs7610922 -0.0091692827352366 0.0045378422107767 0.0433184775664217
Filtered coffee (ukb-b-748) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - MR Egger 0.0232194160194998 0.0073715004901502 0.0092439940258212
Instant coffee (ukb-b-930) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs167978 -0.005628640776699 0.0027927839420557 0.0438603545565988
Instant coffee (ukb-b-930) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon rs2472297 0.0048813774899649 0.0021688902261397 0.0244087455230745
Instant coffee (ukb-b-930) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon All - MR Egger 0.0260855941965765 0.0068578376027134 0.0066819412698621