ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweet pepper (ukb-b-10932) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 4 -0.007973985 0.003955079 0.043785586
Scotch egg (ukb-b-13516) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 3 0.071340138 0.032135645 0.026420868
Cereal (ukb-b-15926) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC MR Egger 138 -0.012825113 0.005954348 0.033010258
Low calorie drink (ukb-b-19703) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 7 0.005929225 0.002554253 0.020269871
Leek (ukb-b-2530) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 4 0.014247997 0.005763732 0.013435625
Coleslaw (ukb-b-2691) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Weighted median 4 0.015428928 0.006225518 0.013199656
Coleslaw (ukb-b-2691) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 4 0.013917503 0.004916149 0.004640613
Beef (ukb-b-2862) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 70 -0.005618786 0.002032426 0.005699766
Prune (ukb-b-3022) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Weighted median 6 -0.017163115 0.0075904 0.023749304
Prune (ukb-b-3022) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 6 -0.015922692 0.006109656 0.009156584
Standard tea (ukb-b-3291) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 8 2.02e-05 9.93e-06 0.042122713
Hard cheese (ukb-b-3542) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 3 -0.008166493 0.004126304 0.047801362
Pulses (ukb-b-621) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 6 0.00803536 0.003061556 0.008675077
Liver (ukb-b-6373) (👉 📊) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC Inverse variance weighted 2 0.038281535 0.016596156 0.021074298

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweet pepper (ukb-b-10932) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs113397084 -0.0201953467869475 0.0073103856281682 0.0057350792177885
Sweet pepper (ukb-b-10932) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted -0.0079739845519138 0.003955079473791 0.0437855862443911
Scotch egg (ukb-b-13516) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.0713401383941663 0.0321356454583057 0.0264208684615906
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs10799311 0.03423943131178 0.0168071016952768 0.0416299815794016
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs12523398 -0.037287104816044 0.0157734569763564 0.0180829817745981
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs4739095 -0.0289759513742072 0.0137755720681507 0.0354281994608925
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs491711 0.0332958035676092 0.0139318133207854 0.0168524242590555
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs4917456 0.0482890252215406 0.0178140561274595 0.0067136077816719
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs72753733 -0.0413400387273211 0.0169939522974846 0.0149895107603163
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs7999064 -0.0391526081368372 0.0169439571898568 0.02084875841382
Cereal (ukb-b-15926) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - MR Egger -0.0128251134364447 0.005954348369515 0.0330102582743739
Low calorie drink (ukb-b-19703) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs55848565 0.0129590997104311 0.0059466661064366 0.0293152539785864
Low calorie drink (ukb-b-19703) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs9657638 0.0151747408670343 0.0054460011842002 0.0053296964015065
Low calorie drink (ukb-b-19703) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.0059292251486304 0.0025542531645236 0.0202698711313969
Leek (ukb-b-2530) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs3862773 0.0252756038511345 0.0118312595011542 0.0326516355168185
Leek (ukb-b-2530) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.0142479967115735 0.0057637324265014 0.0134356246001267
Coleslaw (ukb-b-2691) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs6666162 0.0221167058992221 0.0095199488582728 0.0201686323839608
Coleslaw (ukb-b-2691) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.013917503258365 0.0049161493674089 0.0046406132583448
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs10247400 -0.0383541182255542 0.0187185107029634 0.0404626906303284
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs11904006 0.0391176378495162 0.0186801097995011 0.0362528852617064
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs267733 0.0381453563045308 0.0180816688072988 0.0348915476424866
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs4759074 -0.0486868429087694 0.017347322417321 0.0050068733000557
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs62169335 -0.0326992405753292 0.0157273999925668 0.0376058040106872
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs7791463 -0.0370082714909001 0.0157219069881426 0.0185760994109792
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs7902949 0.0388291672198602 0.018464989906614 0.0354785844502147
Beef (ukb-b-2862) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted -0.0056187855024432 0.0020324256414093 0.0056997657370065
Prune (ukb-b-3022) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted -0.0159226919669337 0.0061096561138649 0.0091565840699515
Standard tea (ukb-b-3291) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 2.01860964090157e-05 9.93260803327442e-06 0.042122712827511
Hard cheese (ukb-b-3542) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs13287896 -0.0153529051631148 0.006866022231755 0.0253471973629797
Hard cheese (ukb-b-3542) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted -0.0081664930781954 0.0041263043432934 0.0478013616764438
Pulses (ukb-b-621) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs7115225 0.0201582750798965 0.0079632940105067 0.0113608507411902
Pulses (ukb-b-621) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.008035359952219 0.0030615558153994 0.0086750767646276
Liver (ukb-b-6373) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC rs12548207 0.0515998283634307 0.0234263193951761 0.0276198907592851
Liver (ukb-b-6373) Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC All - Inverse variance weighted 0.0382815347676431 0.0165961556514135 0.0210742982803954