ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Cheese (ukb-b-1489) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 102 -0.002034387 0.000917276 0.026564601
Broccoli (ukb-b-15601) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 2 0.007292811 0.00283995 0.010230596
Salted nuts (ukb-b-15960) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Weighted median 3 -0.032456694 0.010733365 0.002495334
Salted nuts (ukb-b-15960) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 3 -0.029399708 0.008547284 0.000582456
Espresso (ukb-b-19142) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 4 -0.013971999 0.006795864 0.039786731
Cherry (ukb-b-2221) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Weighted median 6 0.012307178 0.006208607 0.047448268
Cherry (ukb-b-2221) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 6 0.009897976 0.004957261 0.045861876
Baked bean (ukb-b-4058) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Wald ratio 1 -0.014033433 0.00583198 0.016115484
Whole egg (ukb-b-4075) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Inverse variance weighted 2 -0.013543559 0.003714101 0.000265811
Coffee (ukb-b-5237) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint MR Egger 69 0.005271333 0.002574541 0.044534302
Tofu (ukb-b-5522) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Wald ratio 1 0.062980618 0.028629503 0.027817521
Tea (ukb-b-6066) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Simple mode 85 0.009032486 0.003971923 0.02551075
Chocolate sweet (ukb-b-9835) (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint Wald ratio 1 -0.013737993 0.006643287 0.038644635

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Cheese (ukb-b-1489) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs17704703 0.0217847909504068 0.0109311755581157 0.0462718855416566
Cheese (ukb-b-1489) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs2352974 -0.0192026736197335 0.0077503242005352 0.0132246843139664
Cheese (ukb-b-1489) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs34205186 -0.0256765408549656 0.0106888639175063 0.0162978296084022
Cheese (ukb-b-1489) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted -0.0020343868921842 0.000917276056223 0.0265646013023514
Broccoli (ukb-b-15601) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs7540542 0.0090071359679455 0.0039258678062713 0.0217730172984928
Broccoli (ukb-b-15601) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted 0.0072928112872368 0.0028399502710045 0.0102305964813274
Salted nuts (ukb-b-15960) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs4972701 -0.033711368112533 0.0149839118532238 0.0244592569528461
Salted nuts (ukb-b-15960) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs9613266 -0.0382975403758744 0.0144317720254021 0.0079615441506277
Salted nuts (ukb-b-15960) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted -0.0293997081196231 0.0085472840824489 0.000582456229663
Espresso (ukb-b-19142) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs3102538 -0.0336668477147869 0.0108173877427455 0.0018564203709561
Espresso (ukb-b-19142) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted -0.0139719986433893 0.0067958637157955 0.0397867311179952
Cherry (ukb-b-2221) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted 0.0098979764941854 0.0049572610849428 0.0458618763184658
Baked bean (ukb-b-4058) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs11610708 -0.0140334332583895 0.0058319801815305 0.0161154839270823
Whole egg (ukb-b-4075) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs2184358 -0.0161340922195237 0.0051768210647703 0.0018294821909179
Whole egg (ukb-b-4075) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs2420110 -0.010795737476347 0.0053316639871763 0.0428843555560729
Whole egg (ukb-b-4075) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - Inverse variance weighted -0.0135435586305789 0.0037141006635809 0.0002658112658768
Coffee (ukb-b-5237) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs13088645 -0.0387866762478923 0.0147321664707848 0.0084687102638733
Coffee (ukb-b-5237) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs2465037 0.0264993368887384 0.0111404573116247 0.017375792945351
Coffee (ukb-b-5237) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs6544966 -0.0425773216971384 0.0143958267257343 0.0031002847617208
Coffee (ukb-b-5237) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint All - MR Egger 0.0052713326129523 0.0025745409795556 0.0445343021805435
Tofu (ukb-b-5522) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs6597123 0.0629806183251885 0.028629502507241 0.0278175212263265
Tea (ukb-b-6066) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs10764990 -0.0197187997309402 0.0094024904434564 0.0359768459749868
Tea (ukb-b-6066) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs12295734 -0.0225979408893228 0.0109000621283394 0.0381542500257236
Tea (ukb-b-6066) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs17685 0.0117325876308773 0.0054135397021525 0.0302144775528321
Chocolate sweet (ukb-b-9835) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint rs7959426 -0.0137379926134757 0.0066432874317689 0.0386446348602041