ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC (ukb-b-8379)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Grape (ukb-b-12051) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 2 -0.014721125 0.005042383 0.003506182
Double crust pastry (ukb-b-1255) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Weighted median 5 -0.016430202 0.007973863 0.039350079
Other alcohol (ukb-b-12901) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Weighted median 7 -0.027172249 0.01239771 0.028400084
Other alcohol (ukb-b-12901) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 7 -0.021285603 0.009962777 0.032637614
Poultry (ukb-b-16010) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 4 -0.007610523 0.003497601 0.029560769
Espresso (ukb-b-19142) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 9 -0.014623249 0.005275506 0.005572778
Scotch pancake (ukb-b-2035) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Weighted median 5 0.038049009 0.017223894 0.027168875
Mushroom (ukb-b-4043) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 6 0.006904857 0.002832807 0.01479081
Dairy smoothie (ukb-b-4955) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Weighted median 4 -0.022058865 0.0091942 0.016430247
Dairy smoothie (ukb-b-4955) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 4 -0.016653185 0.00744766 0.025349867
Oatcakes (ukb-b-6298) (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC Inverse variance weighted 3 -0.013276 0.005033931 0.008356824

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Grape (ukb-b-12051) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs10497191 -0.0156479845639 0.0071625312792064 0.0289108248116583
Grape (ukb-b-12051) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0147211247009021 0.0050423826263017 0.0035061824055053
Other alcohol (ukb-b-12901) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs7695589 -0.05548112997664 0.0203736335413148 0.0064656256463056
Other alcohol (ukb-b-12901) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0212856030524621 0.0099627767380149 0.0326376140376689
Poultry (ukb-b-16010) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs10810867 -0.0142148181879512 0.0072322151386359 0.049358005132464
Poultry (ukb-b-16010) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0076105229695159 0.0034976013838169 0.0295607690624432
Espresso (ukb-b-19142) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs10245400 -0.0362174576470128 0.0148290621698815 0.0145928163376129
Espresso (ukb-b-19142) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs12465802 -0.0409918883296328 0.0155786531265757 0.0085062476154105
Espresso (ukb-b-19142) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0146232494917606 0.0052755064798038 0.0055727782660369
Mushroom (ukb-b-4043) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs12626372 0.0158023374532053 0.0067851302781536 0.0198608690750732
Mushroom (ukb-b-4043) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted 0.0069048565212491 0.0028328069720259 0.0147908095136073
Dairy smoothie (ukb-b-4955) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0166531846976215 0.0074476601801851 0.0253498667350458
Oatcakes (ukb-b-6298) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC rs17713739 -0.0204460165252715 0.0088110647470086 0.0203142080887904
Oatcakes (ukb-b-6298) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC All - Inverse variance weighted -0.0132760000745325 0.0050339312646484 0.0083568244848813