ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC (ukb-b-8539)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Pineapple (ukb-b-1164) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Wald ratio 1 0.028437772 0.009765249 0.003589616
Orange (ukb-b-13520) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Weighted median 3 0.009027271 0.004262713 0.034198038
Orange (ukb-b-13520) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Inverse variance weighted 3 0.006971534 0.003329694 0.036282629
Sweetcorn (ukb-b-13567) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Inverse variance weighted 7 -0.005252562 0.002600044 0.04336457
Beef (ukb-b-2862) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Inverse variance weighted 36 0.00469993 0.002369157 0.047278281
Mushroom (ukb-b-4043) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Inverse variance weighted 3 -0.00530587 0.00263229 0.043832842
Pork (ukb-b-5640) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC MR Egger 39 -0.044603837 0.018140404 0.01874028
Garlic bread (ukb-b-602) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC Inverse variance weighted 2 -0.015033497 0.006928775 0.030028123
Tea (ukb-b-6066) (👉 📊) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC MR Egger 66 -0.007805507 0.003157765 0.016111876

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Pineapple (ukb-b-1164) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs2454222 0.0284377724705258 0.0097652488722089 0.0035896163639721
Orange (ukb-b-13520) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - Inverse variance weighted 0.0069715335200947 0.003329694301511 0.0362826290312821
Sweetcorn (ukb-b-13567) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - Inverse variance weighted -0.0052525616415185 0.0026000444967429 0.043364570488911
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs2965199 -0.0262825828061909 0.0126851262440601 0.0382727845376895
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs35800274 0.0360028614942309 0.012733311887124 0.0046919665324377
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs4676964 0.0188547400268099 0.0077684167958482 0.015219975652816
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs4759074 -0.0259400363664535 0.0118888225563156 0.0291180660963941
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs7601686 0.03676348423932 0.0121219318536469 0.0024229021053125
Beef (ukb-b-2862) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - Inverse variance weighted 0.0046999302320593 0.0023691567774525 0.0472782805698872
Mushroom (ukb-b-4043) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - Inverse variance weighted -0.0053058704366104 0.0026322904299325 0.0438328415869883
Pork (ukb-b-5640) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - MR Egger -0.0446038374333812 0.0181404037318981 0.0187402802809891
Garlic bread (ukb-b-602) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs7281491 -0.0198541300371964 0.0093803839799263 0.0342973481246442
Garlic bread (ukb-b-602) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - Inverse variance weighted -0.0150334972916072 0.0069287754680172 0.0300281232548439
Tea (ukb-b-6066) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs10281069 0.0226606848562534 0.0104664387881747 0.0303815039673328
Tea (ukb-b-6066) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs1421488 0.0255180761178406 0.0099146665171227 0.0100596978888974
Tea (ukb-b-6066) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC rs713598 -0.0216086557337892 0.0078198687756122 0.0057219870654479
Tea (ukb-b-6066) Operative procedures - main OPCS: W15.3 Osteotomy of first metatarsal bone NEC All - MR Egger -0.0078055065563312 0.0031577648225874 0.0161118760810393