ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Beef (ukb-b-10829) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 5 0.007947105 0.003930334 0.04317714
Bread (ukb-b-11348) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Simple mode 76 -0.012071452 0.005613695 0.034749737
Crisp (ukb-b-12602) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 4 -0.008560838 0.004348943 0.049012011
Crisp (ukb-b-12602) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 4 -0.009593298 0.004061977 0.018189813
Other drink (ukb-b-1310) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 4 -0.018890034 0.008142269 0.020341086
Other drink (ukb-b-1310) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 4 -0.01716492 0.00667056 0.01007527
Dark chocolate (ukb-b-16139) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 4 -0.01553257 0.006235279 0.012735587
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 115 -0.004421282 0.002101551 0.035394268
Dried fruit (ukb-b-16576) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 115 -0.005023727 0.001385821 0.000288859
Ice-cream (ukb-b-17189) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 7 -0.008568336 0.004195908 0.041144654
Ice-cream (ukb-b-17189) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 7 -0.006315182 0.003166754 0.046128767
Espresso (ukb-b-19142) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 6 -0.010474771 0.005241309 0.045662165
Coleslaw (ukb-b-2691) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 4 0.011958651 0.00526402 0.023100316
Coleslaw (ukb-b-2691) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 4 0.012357318 0.004414228 0.00511931
Cabbage/kale (ukb-b-2975) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 2 -0.009144604 0.004646598 0.049065581
Standard tea (ukb-b-3291) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Weighted median 8 2.78e-05 1.19e-05 0.01969549
Green tea (ukb-b-4078) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 7 8.64e-05 3.6e-05 0.01639866
Lamb (ukb-b-530) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 4 -0.012149057 0.005454603 0.025926982
Pork (ukb-b-5640) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 58 0.005288547 0.002363953 0.025275738
Fresh tomato (ukb-b-730) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure Inverse variance weighted 3 0.004291665 0.002170295 0.047990058
Poultry (ukb-b-8006) (👉 📊) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure MR Egger 52 -0.064414734 0.024058568 0.010009894

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Beef (ukb-b-10829) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs6739502 0.0204642980168299 0.0066346636484425 0.0020392787977462
Beef (ukb-b-10829) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted 0.0079471045658471 0.0039303336053773 0.043177140001193
Bread (ukb-b-11348) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs10966045 0.0370066129909313 0.0137302004946587 0.0070331376261393
Bread (ukb-b-11348) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs2068650 -0.0206948629645573 0.0097157411393313 0.0331687724514961
Bread (ukb-b-11348) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs838133 0.0256092902852074 0.0126111277052163 0.0422864565113561
Bread (ukb-b-11348) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs9897045 0.0348004716324782 0.0129252931225146 0.0070933018298511
Crisp (ukb-b-12602) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs72721656 -0.0139821525193068 0.006518962435849 0.0319653826000551
Crisp (ukb-b-12602) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs7377083 -0.0191007035526743 0.0066476757548281 0.0040622040657375
Crisp (ukb-b-12602) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0095932976853078 0.0040619765002827 0.0181898130845312
Other drink (ukb-b-1310) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs62314642 -0.0278159604107308 0.0136721888540738 0.0419020028609072
Other drink (ukb-b-1310) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0171649199630525 0.0066705599903976 0.0100752704189343
Dark chocolate (ukb-b-16139) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs10806742 -0.0326874299798342 0.0126275599372619 0.0096372982196159
Dark chocolate (ukb-b-16139) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0155325704862066 0.0062352786430965 0.0127355867864666
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs10268994 -0.0340106971219074 0.0172422650884291 0.0485503787170481
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs11082011 -0.0413362890943763 0.0156492055664893 0.0082556740050227
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs11586016 -0.0341729954303323 0.0141381307082884 0.0156455706062015
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs13016580 -0.041260655931802 0.0164169657006503 0.0119609722411472
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs2165150 -0.0307964337003351 0.0154580540928674 0.0463427448377441
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs3757323 -0.0338269676056021 0.0157344378751433 0.031565641786369
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs9300104 -0.0356419684243544 0.017569616282717 0.0424976280971431
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs9860336 0.0360440705940264 0.0170757403474463 0.0347864955206677
Dried fruit (ukb-b-16576) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0050237267840419 0.0013858207799743 0.0002888594395132
Ice-cream (ukb-b-17189) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0063151821252152 0.0031667538526065 0.0461287674185069
Espresso (ukb-b-19142) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0104747712160036 0.005241308958864 0.045662164570854
Coleslaw (ukb-b-2691) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted 0.0123573182012784 0.004414228359416 0.0051193097811575
Cabbage/kale (ukb-b-2975) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs10962528 -0.0135142731957997 0.0064029615767351 0.0348042559131141
Cabbage/kale (ukb-b-2975) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0091446038033045 0.0046465978588922 0.0490655809347748
Standard tea (ukb-b-3291) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs2472297 3.02554004408523e-05 1.49675238795004e-05 0.0432380452811996
Standard tea (ukb-b-3291) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs7233417 6.78426733435028e-05 3.12200643075377e-05 0.0297767649759698
Green tea (ukb-b-4078) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs9327186 0.0001022976191093 3.89399355618622e-05 0.0086125678249702
Green tea (ukb-b-4078) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted 8.6425524362483e-05 3.60118369572045e-05 0.0163986595324247
Lamb (ukb-b-530) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted -0.0121490571623844 0.0054546028243417 0.0259269820784366
Pork (ukb-b-5640) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs10884893 -0.0510236409287105 0.0191418173611307 0.0076860474822442
Pork (ukb-b-5640) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs13009921 0.038502458919721 0.019388300863159 0.0470488267937143
Pork (ukb-b-5640) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs6909236 0.0484942453336514 0.0194595397028204 0.0127006329809042
Pork (ukb-b-5640) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs838133 0.0259705903950654 0.0127890475840799 0.042286456511356
Pork (ukb-b-5640) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted 0.0052885473338162 0.0023639534168435 0.0252757379395665
Fresh tomato (ukb-b-730) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs12607299 0.0086111905801575 0.0036440154788972 0.0181225424825159
Fresh tomato (ukb-b-730) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - Inverse variance weighted 0.0042916646969701 0.002170295427616 0.047990058273101
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs11678980 0.0325213009149253 0.0146392234507639 0.0263158853158231
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs2426440 -0.0273406313237116 0.0135758667106448 0.0440185379479344
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs34344257 -0.0374746931292842 0.0160387772995377 0.0194649055920009
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs4700474 0.0381939931500834 0.0152476508298937 0.0122482553023797
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs7464104 -0.0319267326775832 0.0159587893106778 0.045438360337381
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs77779142 -0.0374471637350551 0.0134975194056069 0.005530809398386
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure rs9997448 -0.0349716185998509 0.0133472851327332 0.0087896322566424
Poultry (ukb-b-8006) Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure All - MR Egger -0.064414733745018 0.0240585680594333 0.0100098941269911