ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other/unspecified rheumatoid arthritis (ukb-d-RHEUMA_NOS)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other drink (ukb-b-1310) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 17 0.014505891 0.005416199 0.017192215
Lamb/mutton (ukb-b-14179) (👉 📊) Other/unspecified rheumatoid arthritis Weighted median 128 0.006886749 0.002432401 0.004636556
Plum (ukb-b-14182) (👉 📊) Other/unspecified rheumatoid arthritis Weighted median 10 0.006832662 0.00326095 0.03614452
Plum (ukb-b-14182) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 10 0.005028941 0.002500501 0.044307186
Mozzarella (ukb-b-14505) (👉 📊) Other/unspecified rheumatoid arthritis Weighted median 19 -0.015234313 0.00774895 0.049300433
Cheese (ukb-b-1489) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 202 -0.001850225 0.000821321 0.024275447
Cereal (ukb-b-15926) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 175 -0.002943946 0.001101477 0.007523781
Pea (ukb-b-15945) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 9 0.00406999 0.001934601 0.035396948
Dark chocolate (ukb-b-16139) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 16 0.016211316 0.005980889 0.016904694
Dark chocolate (ukb-b-16139) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 16 0.009301415 0.003183983 0.003485584
Non-oily fish (ukb-b-17627) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 67 -0.016833175 0.00637872 0.010397766
Fruit smoothie (ukb-b-1780) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 18 -0.017889554 0.007347695 0.026984997
Cereal bar (ukb-b-18788) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 11 -0.012302153 0.004403138 0.020918353
Oily fish (ukb-b-2209) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 170 -0.002349975 0.000999462 0.018710998
Prune (ukb-b-3022) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 14 0.007995492 0.003795851 0.035171636
Standard tea (ukb-b-3291) (👉 📊) Other/unspecified rheumatoid arthritis Weighted median 15 2.49e-05 1.03e-05 0.015431485
Standard tea (ukb-b-3291) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 15 1.68e-05 7.32e-06 0.021558913
Green tea (ukb-b-4078) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 95 -4.86e-05 2.08e-05 0.019242038
Bacon (ukb-b-4414) (👉 📊) Other/unspecified rheumatoid arthritis Weighted median 12 -0.006869881 0.002499881 0.005994475
Bacon (ukb-b-4414) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 12 -0.005127935 0.002261711 0.02337304
Olives (ukb-b-5232) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 20 0.017388147 0.007469675 0.031782643
Olives (ukb-b-5232) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 20 0.009131064 0.003698045 0.013543079
Baguette (ukb-b-5277) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 13 0.017803765 0.006031422 0.013166116
Breaded fish (ukb-b-5753) (👉 📊) Other/unspecified rheumatoid arthritis MR Egger 18 0.018463156 0.007796092 0.03080153
Tea (ukb-b-6066) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 139 0.002085041 0.000991145 0.035407429
Chocolate biscuits (ukb-b-9886) (👉 📊) Other/unspecified rheumatoid arthritis Inverse variance weighted 9 0.003169032 0.001404077 0.024006706

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other drink (ukb-b-1310) Other/unspecified rheumatoid arthritis rs529703549 0.0146721777960299 0.0058282728034385 0.0118219697100578
Other drink (ukb-b-1310) Other/unspecified rheumatoid arthritis All - MR Egger 0.0145058905388587 0.0054161988067812 0.0171922148519943
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs10905778 -0.046713923317052 0.0188655452602715 0.0132807700625637
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs11672035 -0.0430196327153627 0.0189507671225902 0.0232031287942989
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs12634740 -0.0332641023099038 0.0160481808268068 0.0381941854910283
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs137969241 -0.0433094101374897 0.0204447328734248 0.034144152809876
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs139237013 0.0512425061776082 0.0158195979660192 0.0011987440486965
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs17270057 -0.0362091312147819 0.0174670639279872 0.0381727713881809
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs1958801 0.0415128282820377 0.0172497263501086 0.0161027231836142
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs3737627 0.0420957849406238 0.0205338640219235 0.0403579504981364
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs4449668 0.055527431571191 0.0196905208263363 0.0048022411828703
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs4676964 0.0364106746444341 0.0181831768572596 0.0452377020486779
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs62169335 0.0398737646867083 0.0191415136653902 0.0372417400823989
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs653149 0.0350018074912137 0.0178490046093913 0.0498796146788264
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs673696 0.0390770378236246 0.0163008191747573 0.0165189281607564
Lamb/mutton (ukb-b-14179) Other/unspecified rheumatoid arthritis rs994270 -0.0435531501074305 0.0168578353003472 0.0097787782864581
Plum (ukb-b-14182) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0050289410589418 0.0025005014685939 0.0443071858226415
Mozzarella (ukb-b-14505) Other/unspecified rheumatoid arthritis rs12878562 0.0524212861155953 0.0242624346963938 0.030726666604773
Mozzarella (ukb-b-14505) Other/unspecified rheumatoid arthritis rs142176727 -0.0492001448472713 0.0245473877788665 0.0450387384334332
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs1032001 0.0331806631990633 0.0125357845519065 0.0081239213965083
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs11735256 0.0312354536778126 0.0122400917569446 0.0107138180501962
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs2245959 -0.0326525831741449 0.0126024496287525 0.0095705519567964
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs34453616 -0.0305082198573445 0.0133707899454552 0.0225066673155725
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs614132 -0.0301993984922559 0.0116403672641997 0.009476494376769
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs6498981 -0.0301996427896753 0.0132183276374315 0.0223316248119893
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs6873324 -0.0224440953464886 0.0113994197137041 0.048966813681102
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis rs72829857 -0.029721190048478 0.0136433135648137 0.0293730218030683
Cheese (ukb-b-1489) Other/unspecified rheumatoid arthritis All - Inverse variance weighted -0.0018502245920324 0.0008213212752345 0.0242754472369968
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs10737693 -0.0324334761580757 0.0155975652365803 0.0375811951633803
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs1397440 -0.0406181278690391 0.0160845599096733 0.0115603880828949
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs141612194 -0.0329901147959184 0.0161267219387755 0.0407878509375779
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs186852039 0.0407066667195174 0.015704228980946 0.0095396722272871
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs2504706 -0.0242018119509552 0.0090901739890974 0.0077582253336528
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs2799849 -0.025382880873395 0.0121387147271857 0.0365219470063698
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs3021529 -0.0441690983975588 0.0162662787013723 0.006620012471184
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis rs491711 0.0274976258715832 0.012994139538863 0.0343315451364922
Cereal (ukb-b-15926) Other/unspecified rheumatoid arthritis All - Inverse variance weighted -0.0029439461465693 0.0011014772236125 0.0075237811757193
Pea (ukb-b-15945) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0040699899173805 0.0019346008256191 0.0353969478403333
Dark chocolate (ukb-b-16139) Other/unspecified rheumatoid arthritis rs150993006 0.0311110110254378 0.013001080925272 0.0167132577975775
Dark chocolate (ukb-b-16139) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0093014151443359 0.0031839834187419 0.0034855840112323
Dark chocolate (ukb-b-16139) Other/unspecified rheumatoid arthritis All - MR Egger 0.0162113155795795 0.0059808887841284 0.0169046942225561
Non-oily fish (ukb-b-17627) Other/unspecified rheumatoid arthritis rs62034298 -0.0432545535885473 0.0177284463475427 0.0146938117250973
Non-oily fish (ukb-b-17627) Other/unspecified rheumatoid arthritis rs67646802 0.0381744853460564 0.0170655314037247 0.0252905853397245
Non-oily fish (ukb-b-17627) Other/unspecified rheumatoid arthritis rs78744083 -0.0459461815544374 0.0190936574853807 0.0161124524347429
Non-oily fish (ukb-b-17627) Other/unspecified rheumatoid arthritis rs78769094 -0.0458381464294061 0.0180249724568491 0.0109894035637917
Non-oily fish (ukb-b-17627) Other/unspecified rheumatoid arthritis All - MR Egger -0.0168331746845192 0.0063787197571792 0.0103977657819257
Fruit smoothie (ukb-b-1780) Other/unspecified rheumatoid arthritis rs67791558 0.0295492568749007 0.0150635828962009 0.0498049522916108
Fruit smoothie (ukb-b-1780) Other/unspecified rheumatoid arthritis All - MR Egger -0.0178895538129693 0.0073476954020783 0.0269849974964241
Cereal bar (ukb-b-18788) Other/unspecified rheumatoid arthritis rs115958455 -0.0140354033194119 0.0066522542614782 0.0348694044308559
Cereal bar (ukb-b-18788) Other/unspecified rheumatoid arthritis rs11862422 0.0148602035850014 0.0074187368617258 0.0451704360561962
Cereal bar (ukb-b-18788) Other/unspecified rheumatoid arthritis rs74760533 -0.0154503339609207 0.0067640519135589 0.0223607646092608
Cereal bar (ukb-b-18788) Other/unspecified rheumatoid arthritis All - MR Egger -0.0123021526899282 0.0044031383367665 0.020918353454909
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs10137526 0.0316803854119134 0.0135521604829934 0.019404732087739
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs1053924 -0.0260886738895774 0.0120490145124535 0.0303714342253024
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs12855717 -0.0235814158857872 0.0114934013638817 0.0401954060826831
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs141652736 -0.0348394143516517 0.0153900532029045 0.0235887699384939
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs16891727 -0.017380688358287 0.0086899436276473 0.0454903102442862
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs28533540 -0.0221702488031088 0.0096195217899071 0.0211825831228598
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs77258251 0.0377176016377965 0.0146238303123218 0.0099032991594637
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis rs7919624 -0.0322890053608083 0.0143555072839236 0.0244971238427373
Oily fish (ukb-b-2209) Other/unspecified rheumatoid arthritis All - Inverse variance weighted -0.0023499745315725 0.0009994621031887 0.0187109983664319
Prune (ukb-b-3022) Other/unspecified rheumatoid arthritis rs11247295 0.0372703738599877 0.0136681638141586 0.0063951437406069
Prune (ukb-b-3022) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0079954919777446 0.0037958507794892 0.0351716358284901
Standard tea (ukb-b-3291) Other/unspecified rheumatoid arthritis rs908817 6.39748803919025e-05 2.83280428528916e-05 0.0239233089763709
Standard tea (ukb-b-3291) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 1.68273969438023e-05 7.32246599192744e-06 0.0215589126701187
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs10192021 -0.0005578570258382 0.0002536848081323 0.0278767639514828
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs10833476 -0.0006329462885166 0.0002288588788922 0.0056807393441948
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs115739961 0.0004782707065312 0.0002420469339386 0.0481613448186325
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs116363527 -0.0006835475889136 0.0002421310845977 0.0047569501292316
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs17313318 -0.000663419258011 0.0002430174570157 0.0063348872772701
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis rs77540739 -0.0004773623177312 0.0002241748109902 0.0332195302660168
Green tea (ukb-b-4078) Other/unspecified rheumatoid arthritis All - Inverse variance weighted -4.8644489365212e-05 2.07810638749481e-05 0.0192420379054974
Bacon (ukb-b-4414) Other/unspecified rheumatoid arthritis rs66626876 -0.0143317626804476 0.0068013269067536 0.0351001625753981
Bacon (ukb-b-4414) Other/unspecified rheumatoid arthritis rs66799945 -0.0151017964071856 0.0065713995737338 0.0215555523447514
Bacon (ukb-b-4414) Other/unspecified rheumatoid arthritis All - Inverse variance weighted -0.0051279346792657 0.0022617107107386 0.0233730395481845
Olives (ukb-b-5232) Other/unspecified rheumatoid arthritis rs73119845 0.0414601024340602 0.0161223536477536 0.0101232354374236
Olives (ukb-b-5232) Other/unspecified rheumatoid arthritis rs887263 0.0378280074386767 0.0165711047192657 0.0224439672147212
Olives (ukb-b-5232) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0091310640434042 0.0036980452552768 0.013543079023098
Olives (ukb-b-5232) Other/unspecified rheumatoid arthritis All - MR Egger 0.0173881468924303 0.0074696752844582 0.031782642863882
Baguette (ukb-b-5277) Other/unspecified rheumatoid arthritis rs2362311 0.0251637012676729 0.0081963066025803 0.0021396784691164
Baguette (ukb-b-5277) Other/unspecified rheumatoid arthritis rs4747342 0.0190650972600431 0.0085444256202378 0.0256618805751055
Baguette (ukb-b-5277) Other/unspecified rheumatoid arthritis rs73101535 0.0236271974785416 0.007060963295032 0.0008193556151749
Baguette (ukb-b-5277) Other/unspecified rheumatoid arthritis All - MR Egger 0.0178037647928549 0.0060314224126205 0.0131661164775556
Breaded fish (ukb-b-5753) Other/unspecified rheumatoid arthritis rs116624476 0.0349134407925701 0.0152209531531783 0.0218034300164717
Breaded fish (ukb-b-5753) Other/unspecified rheumatoid arthritis rs150700219 0.0539914643531799 0.0157817513068335 0.0006236091243846
Breaded fish (ukb-b-5753) Other/unspecified rheumatoid arthritis All - MR Egger 0.0184631560783441 0.0077960920690301 0.030801529558817
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs11752836 0.0264730252921808 0.0127386293736657 0.037693791727911
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs11878917 -0.0283158192646552 0.0138620982428508 0.0410842086345772
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs12752825 0.0314872188680578 0.0131312007908767 0.0164896662206639
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs12920407 0.0329048028830075 0.0146882691809057 0.0250773131712442
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs1640297 0.0328519915085835 0.0135757975243062 0.0155250302327494
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs2497305 0.0332290793384651 0.0133349211188172 0.0127067455166323
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs6829 0.0261205239881507 0.0120085093527353 0.0296175372302524
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs7172571 -0.0279934675064762 0.0139531982360535 0.0448306245674853
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs79494947 0.0314161811112256 0.0133752685340995 0.0188326952800137
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs897623 0.0338818000822176 0.0137932146282877 0.0140332672688297
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs901746 0.0247447907931412 0.0121384702621974 0.0414956819807172
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis rs9262602 0.0395842438015325 0.014235133875244 0.005423471281342
Tea (ukb-b-6066) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0020850407417552 0.0009911454018827 0.0354074285867639
Chocolate biscuits (ukb-b-9886) Other/unspecified rheumatoid arthritis rs8076469 0.0118169931712616 0.0043741443078447 0.0069015981685912
Chocolate biscuits (ukb-b-9886) Other/unspecified rheumatoid arthritis All - Inverse variance weighted 0.0031690324932674 0.0014040769810628 0.0240067064640887