Ankle spacing width (ukb-e-3143_EAS)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Chocolate-covered raisin (ukb-b-1160) (👉 📊)	Ankle spacing width	Weighted median	18	2.321284579	0.985246951	0.018470759
Chocolate-covered raisin (ukb-b-1160) (👉 📊)	Ankle spacing width	Weighted mode	18	2.124763693	0.974068988	0.043490981
Celery (ukb-b-14145) (👉 📊)	Ankle spacing width	Inverse variance weighted	7	-0.80384106	0.385329377	0.036968286
Shellfish (ukb-b-143) (👉 📊)	Ankle spacing width	Inverse variance weighted	9	2.122053345	0.918502247	0.020869286
Shellfish (ukb-b-143) (👉 📊)	Ankle spacing width	Weighted mode	9	3.565271861	1.145381685	0.014385814
Lobster/crab (ukb-b-14746) (👉 📊)	Ankle spacing width	MR Egger	15	-7.43369608	3.285406986	0.041428506
Savoury biscuits (ukb-b-1503) (👉 📊)	Ankle spacing width	MR Egger	10	9.027717249	3.759614833	0.043093622
Low fat hard cheese (ukb-b-18079) (👉 📊)	Ankle spacing width	MR Egger	6	-10.35842695	3.587394815	0.044677164
Low calorie drink (ukb-b-19703) (👉 📊)	Ankle spacing width	MR Egger	11	2.584497648	1.029017846	0.03322255
Butternut squash (ukb-b-20341) (👉 📊)	Ankle spacing width	Weighted median	6	5.290447299	1.813094674	0.003523859
Butternut squash (ukb-b-20341) (👉 📊)	Ankle spacing width	Inverse variance weighted	6	5.032413316	1.423504031	0.000407421
Butternut squash (ukb-b-20341) (👉 📊)	Ankle spacing width	Simple mode	6	6.544979441	2.470618208	0.045474188
Butternut squash (ukb-b-20341) (👉 📊)	Ankle spacing width	Weighted mode	6	5.434134126	1.884527817	0.034444953
Baked bean (ukb-b-4058) (👉 📊)	Ankle spacing width	MR Egger	7	-4.305255668	1.6297554	0.045884563
Cucumber (ukb-b-588) (👉 📊)	Ankle spacing width	MR Egger	7	2.700023377	1.035295707	0.047786661
Crumble (ukb-b-7641) (👉 📊)	Ankle spacing width	MR Egger	8	5.842994811	1.875935456	0.020724078
Other grain (ukb-b-8765) (👉 📊)	Ankle spacing width	Simple mode	22	7.049157347	2.684654172	0.015798933

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Chocolate-covered raisin (ukb-b-1160)	Ankle spacing width	rs4244577	-5.2514457616176	2.39357683484663	0.0282372661779377
Chocolate-covered raisin (ukb-b-1160)	Ankle spacing width	rs522980	2.35843186060983	0.94634052941458	0.0126968884851399
Celery (ukb-b-14145)	Ankle spacing width	rs12551354	-0.948185947884252	0.436165536026756	0.0297116662879534
Celery (ukb-b-14145)	Ankle spacing width	All - Inverse variance weighted	-0.803841060431004	0.385329377396084	0.0369682856990827
Shellfish (ukb-b-143)	Ankle spacing width	rs2272317	3.76721181518948	1.32214314026229	0.0043812484896499
Shellfish (ukb-b-143)	Ankle spacing width	All - Inverse variance weighted	2.12205334475535	0.918502246889909	0.0208692860311331
Lobster/crab (ukb-b-14746)	Ankle spacing width	rs116077835	-5.89298084664208	2.93900132931419	0.0449527473104583
Lobster/crab (ukb-b-14746)	Ankle spacing width	rs3134489	-13.8364633048472	6.39077394023313	0.0303824403742537
Lobster/crab (ukb-b-14746)	Ankle spacing width	rs6554575	25.0571091488534	9.44047002494966	0.0079491362334139
Lobster/crab (ukb-b-14746)	Ankle spacing width	All - MR Egger	-7.43369607967785	3.28540698605087	0.0414285058685215
Savoury biscuits (ukb-b-1503)	Ankle spacing width	All - MR Egger	9.02771724896821	3.75961483313884	0.0430936216604837
Low fat hard cheese (ukb-b-18079)	Ankle spacing width	rs72891041	-3.45805876967993	1.55336362811642	0.0260024836009103
Low fat hard cheese (ukb-b-18079)	Ankle spacing width	All - MR Egger	-10.358426947243	3.58739481469409	0.0446771640658221
Low calorie drink (ukb-b-19703)	Ankle spacing width	rs76698704	2.48613092407672	1.13488666983674	0.0284776761244443
Low calorie drink (ukb-b-19703)	Ankle spacing width	All - MR Egger	2.58449764767326	1.02901784607404	0.0332225497748378
Butternut squash (ukb-b-20341)	Ankle spacing width	rs6926290	6.2260338927143	2.86562487114996	0.0298057755505105
Butternut squash (ukb-b-20341)	Ankle spacing width	rs77569241	4.68972787414771	1.94211497266578	0.0157458852239443
Butternut squash (ukb-b-20341)	Ankle spacing width	All - Inverse variance weighted	5.03241331560978	1.42350403127965	0.0004074212799526
Baked bean (ukb-b-4058)	Ankle spacing width	All - MR Egger	-4.30525566832663	1.62975540015157	0.0458845625018085
Cucumber (ukb-b-588)	Ankle spacing width	All - MR Egger	2.70002337713106	1.0352957068983	0.0477866608804642
Crumble (ukb-b-7641)	Ankle spacing width	rs147567393	4.27333934454412	1.78476824677307	0.0166503738517319
Crumble (ukb-b-7641)	Ankle spacing width	All - MR Egger	5.84299481110167	1.87593545575437	0.0207240776220051