Ankle spacing width (left) (ukb-e-4100_AFR)

Mendelian Randomization Results

Intake (exposure)	Outcome	Method	Number of SNPs	b	se	P-value
Sweetcorn (ukb-b-13567) (👉 📊)	Ankle spacing width (left)	MR Egger	15	-2.598443038	1.181206535	0.046512805
Lamb/mutton (ukb-b-14179) (👉 📊)	Ankle spacing width (left)	MR Egger	111	2.139238459	0.960504085	0.027988759
Lobster/crab (ukb-b-14746) (👉 📊)	Ankle spacing width (left)	MR Egger	18	3.96300243	1.859360836	0.048911891
Dark chocolate (ukb-b-16139) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	14	-0.540983462	0.26994641	0.045065752
Other savoury snack (ukb-b-18718) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	9	-1.25229675	0.529623303	0.018054202
Goat's cheese (ukb-b-20122) (👉 📊)	Ankle spacing width (left)	MR Egger	16	1.631633858	0.700756262	0.03538996
Standard tea (ukb-b-3291) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	11	-0.00322131	0.001339745	0.01619813
Baked bean (ukb-b-4058) (👉 📊)	Ankle spacing width (left)	Weighted median	7	-0.827576719	0.413851377	0.045533159
Baked bean (ukb-b-4058) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	7	-0.751537153	0.369813501	0.042132823
Green tea (ukb-b-4078) (👉 📊)	Ankle spacing width (left)	Simple mode	25	-0.021672532	0.00935535	0.029380763
Other bread (ukb-b-4964) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	9	-0.614592943	0.249688237	0.013838004
Olives (ukb-b-5232) (👉 📊)	Ankle spacing width (left)	Inverse variance weighted	13	-0.835746877	0.404415329	0.038776021
Breaded fish (ukb-b-5753) (👉 📊)	Ankle spacing width (left)	Weighted median	13	1.174272578	0.525299268	0.025388779
Breaded fish (ukb-b-5753) (👉 📊)	Ankle spacing width (left)	Weighted mode	13	1.327778554	0.552121799	0.033222538
Doughnut (ukb-b-6214) (👉 📊)	Ankle spacing width (left)	Simple mode	12	3.567119709	1.610516665	0.048799449

Mendelian Randomization Results (Single SNP)

Intake (exposure)	Outcome	SNP	b	se	P-value
Sweetcorn (ukb-b-13567)	Ankle spacing width (left)	rs73265619	-1.74104611494808	0.835293133418232	0.0371280298029782
Sweetcorn (ukb-b-13567)	Ankle spacing width (left)	All - MR Egger	-2.59844303841875	1.1812065345005	0.0465128054148179
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs16891982	4.84586762045648	2.11058962176685	0.021677131671084
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs17594338	7.8099559225272	3.74420078072309	0.0369894363458885
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs276453	-3.80768420313268	1.64009271616211	0.0202530067213827
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs35979472	-6.72469923803078	3.29292057083513	0.0411348026197694
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs61836106	8.13191619647465	2.63307527446092	0.0020125630779785
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs673696	3.63888046116505	1.71799150485437	0.0341664687042003
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	rs72637362	-7.17696071389337	3.29398243998073	0.0293458120841018
Lamb/mutton (ukb-b-14179)	Ankle spacing width (left)	All - MR Egger	2.1392384593048	0.960504085267115	0.0279887590180474
Lobster/crab (ukb-b-14746)	Ankle spacing width (left)	All - MR Egger	3.96300242969332	1.85936083553458	0.0489118906151583
Dark chocolate (ukb-b-16139)	Ankle spacing width (left)	rs10273549	-3.15315516126875	1.5357867284845	0.0400608956717692
Dark chocolate (ukb-b-16139)	Ankle spacing width (left)	rs112868306	-1.21048034934498	0.417467248908297	0.003736610822589
Dark chocolate (ukb-b-16139)	Ankle spacing width (left)	All - Inverse variance weighted	-0.540983462490049	0.269946410031406	0.0450657523840063
Other savoury snack (ukb-b-18718)	Ankle spacing width (left)	rs12061341	-4.97258432397323	1.91834206909052	0.0095384834280038
Other savoury snack (ukb-b-18718)	Ankle spacing width (left)	All - Inverse variance weighted	-1.25229674985085	0.529623303478605	0.0180542019904896
Goat's cheese (ukb-b-20122)	Ankle spacing width (left)	rs150170933	19.9383045064309	10.0803246650022	0.047935172024443
Goat's cheese (ukb-b-20122)	Ankle spacing width (left)	rs7981232	-12.5234372236176	5.36353737966926	0.0195475367746866
Goat's cheese (ukb-b-20122)	Ankle spacing width (left)	All - MR Egger	1.63163385795126	0.700756262178103	0.0353899595774079
Standard tea (ukb-b-3291)	Ankle spacing width (left)	rs10801677	-0.0058226782022816	0.0024102289258096	0.0156998389849544
Standard tea (ukb-b-3291)	Ankle spacing width (left)	All - Inverse variance weighted	-0.0032213099244136	0.0013397448400346	0.0161981301161105
Baked bean (ukb-b-4058)	Ankle spacing width (left)	rs4609980	-1.08552377630176	0.521817698340763	0.0375004106721145
Baked bean (ukb-b-4058)	Ankle spacing width (left)	All - Inverse variance weighted	-0.751537152836939	0.369813500879509	0.0421328228577398
Other bread (ukb-b-4964)	Ankle spacing width (left)	rs74006323	-0.743076084917878	0.265792599605241	0.0051787620097019
Other bread (ukb-b-4964)	Ankle spacing width (left)	rs79862891	-2.58399616799559	1.03701989970315	0.0127114841881073
Other bread (ukb-b-4964)	Ankle spacing width (left)	All - Inverse variance weighted	-0.614592943009037	0.249688237467072	0.0138380035003998
Olives (ukb-b-5232)	Ankle spacing width (left)	rs1382646	-5.45644247324315	2.75034194935094	0.0472654046246712
Olives (ukb-b-5232)	Ankle spacing width (left)	All - Inverse variance weighted	-0.835746877479386	0.404415329047413	0.0387760214983639
Breaded fish (ukb-b-5753)	Ankle spacing width (left)	rs113224254	1.21187242681852	0.546181782886169	0.0264997998102206
Breaded fish (ukb-b-5753)	Ankle spacing width (left)	rs13332415	1.91327268171392	0.790992849019872	0.0155707614073811