ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Ankle spacing width (right) (ukb-e-4119_AFR)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Red wine (ukb-b-13556) (👉 📊) Ankle spacing width (right) Inverse variance weighted 6 0.694414464 0.24426588 0.004471027
Lamb/mutton (ukb-b-14179) (👉 📊) Ankle spacing width (right) MR Egger 111 2.870524777 0.982238619 0.004223526
Lobster/crab (ukb-b-14746) (👉 📊) Ankle spacing width (right) MR Egger 18 4.158865771 1.918158444 0.045569218
Other savoury snack (ukb-b-18718) (👉 📊) Ankle spacing width (right) Inverse variance weighted 9 -1.079221071 0.524341995 0.03956721
Espresso (ukb-b-19142) (👉 📊) Ankle spacing width (right) Weighted median 21 -0.795011947 0.39297646 0.043067752
Espresso (ukb-b-19142) (👉 📊) Ankle spacing width (right) Inverse variance weighted 21 -0.571369374 0.26617645 0.031826635
Low calorie drink (ukb-b-19703) (👉 📊) Ankle spacing width (right) MR Egger 11 -1.645937038 0.597186017 0.022251663
Melon (ukb-b-19862) (👉 📊) Ankle spacing width (right) MR Egger 7 -4.008975461 1.524564018 0.046556366
Cabbage/kale (ukb-b-2975) (👉 📊) Ankle spacing width (right) Inverse variance weighted 10 0.503402882 0.242587281 0.037973442
Fresh fruit (ukb-b-3881) (👉 📊) Ankle spacing width (right) Weighted median 128 -1.151661458 0.501249886 0.021585734
Baked bean (ukb-b-4058) (👉 📊) Ankle spacing width (right) Inverse variance weighted 7 -0.79927522 0.333844341 0.016658691
Baked bean (ukb-b-4058) (👉 📊) Ankle spacing width (right) Simple mode 7 -1.688976944 0.613072759 0.033074849
Apple (ukb-b-4070) (👉 📊) Ankle spacing width (right) Inverse variance weighted 15 -0.433924045 0.190399839 0.022666188
Other bread (ukb-b-4964) (👉 📊) Ankle spacing width (right) Inverse variance weighted 9 -0.507301698 0.247821745 0.040653891
Olives (ukb-b-5232) (👉 📊) Ankle spacing width (right) Inverse variance weighted 13 -0.820635578 0.417449692 0.049318127
Breaded fish (ukb-b-5753) (👉 📊) Ankle spacing width (right) Weighted median 13 1.031280462 0.501729603 0.039835493
Doughnut (ukb-b-6214) (👉 📊) Ankle spacing width (right) Simple mode 12 2.989027855 1.23833206 0.0343852
Fresh tomato (ukb-b-730) (👉 📊) Ankle spacing width (right) Inverse variance weighted 8 -0.447523529 0.221110043 0.04297164
Other cereal (ukb-b-8917) (👉 📊) Ankle spacing width (right) Inverse variance weighted 6 1.580915358 0.615558123 0.010220948

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Red wine (ukb-b-13556) Ankle spacing width (right) rs17478663 1.7455131272907 0.803924696558801 0.0299130662453381
Red wine (ukb-b-13556) Ankle spacing width (right) rs7820063 1.3547767009503 0.643112570612818 0.0351528387610568
Red wine (ukb-b-13556) Ankle spacing width (right) All - Inverse variance weighted 0.6944144635212 0.244265880418031 0.0044710267351179
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs16891982 5.34446454398985 2.17528360275423 0.0140139850637469
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs17594338 8.58659145564662 3.87227751776383 0.0265921856516833
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs276453 -3.97204467233265 1.6892603778886 0.0187053618476016
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs61836106 8.00069982067095 2.71267987578183 0.0031842129846592
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs653149 -7.13756913798261 3.4914031560067 0.0409212706422678
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) rs673696 4.13190230582524 1.76476537216828 0.0192150521568755
Lamb/mutton (ukb-b-14179) Ankle spacing width (right) All - MR Egger 2.87052477724124 0.98223861891211 0.0042235257836079
Lobster/crab (ukb-b-14746) Ankle spacing width (right) rs2808659 -14.6800233549684 7.42742307796757 0.0481024163283534
Lobster/crab (ukb-b-14746) Ankle spacing width (right) All - MR Egger 4.15886577063995 1.91815844391089 0.0455692176351282
Other savoury snack (ukb-b-18718) Ankle spacing width (right) rs12061341 -5.29658776792592 1.97951754452215 0.0074574187518224
Other savoury snack (ukb-b-18718) Ankle spacing width (right) All - Inverse variance weighted -1.07922107071658 0.524341995038537 0.0395672098853032
Espresso (ukb-b-19142) Ankle spacing width (right) rs10000963 -6.05530042807012 2.54616406139876 0.0173971449894585
Espresso (ukb-b-19142) Ankle spacing width (right) All - Inverse variance weighted -0.571369373560152 0.266176449812727 0.0318266347876936
Low calorie drink (ukb-b-19703) Ankle spacing width (right) rs13429737 -1.11840926130211 0.405156723708358 0.0057724242617457
Low calorie drink (ukb-b-19703) Ankle spacing width (right) All - MR Egger -1.64593703813601 0.597186017194038 0.0222516632074699
Melon (ukb-b-19862) Ankle spacing width (right) rs4676860 3.76968921597811 1.72207408908677 0.0285939264227401
Melon (ukb-b-19862) Ankle spacing width (right) rs73212411 7.30962720901234 3.3307176334007 0.0281915644022894
Melon (ukb-b-19862) Ankle spacing width (right) All - MR Egger -4.00897546124848 1.52456401802057 0.0465563656727949
Cabbage/kale (ukb-b-2975) Ankle spacing width (right) All - Inverse variance weighted 0.503402881844473 0.242587280567666 0.0379734421376075
Fresh fruit (ukb-b-3881) Ankle spacing width (right) rs133377 7.64303006675619 3.85681030236815 0.0475131439968622
Fresh fruit (ukb-b-3881) Ankle spacing width (right) rs2609858 6.9946108600606 3.37214422764398 0.0380577312721831
Baked bean (ukb-b-4058) Ankle spacing width (right) rs4894011 -2.22703476970823 1.080265334311 0.0392493838451102
Baked bean (ukb-b-4058) Ankle spacing width (right) All - Inverse variance weighted -0.799275220442453 0.333844340708374 0.0166586905047814
Apple (ukb-b-4070) Ankle spacing width (right) rs1401190 -1.60969856361366 0.784663165817408 0.0402229814052486
Apple (ukb-b-4070) Ankle spacing width (right) rs7902193 -1.89396230577369 0.915492206040896 0.0385656757277567
Apple (ukb-b-4070) Ankle spacing width (right) All - Inverse variance weighted -0.433924045072476 0.190399839480569 0.0226661877287787
Other bread (ukb-b-4964) Ankle spacing width (right) rs79862891 -2.25325769252075 1.06341380759819 0.0340996998938069
Other bread (ukb-b-4964) Ankle spacing width (right) All - Inverse variance weighted -0.507301697661494 0.247821745300433 0.0406538909959233
Olives (ukb-b-5232) Ankle spacing width (right) All - Inverse variance weighted -0.820635578048098 0.417449692355436 0.0493181267839396
Fresh tomato (ukb-b-730) Ankle spacing width (right) All - Inverse variance weighted -0.447523529427627 0.221110043480762 0.0429716401981674
Other cereal (ukb-b-8917) Ankle spacing width (right) rs28496198 2.64767932489451 0.926009644364075 0.0042466386174984
Other cereal (ukb-b-8917) Ankle spacing width (right) All - Inverse variance weighted 1.58091535849699 0.615558123127589 0.0102209478030765