ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Avocado (ukb-b-12236) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted median 12 -0.994365649 0.451754434 0.027727541
Avocado (ukb-b-12236) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 12 -0.912464599 0.33230057 0.00603449
Avocado (ukb-b-12236) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted mode 12 -0.89528677 0.385558125 0.040431257
Naan bread (ukb-b-13281) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 10 -1.66928608 0.71546992 0.019641195
Cottage cheese (ukb-b-14171) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 10 -5.253411864 1.986287258 0.029490983
Mozzarella (ukb-b-14505) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 8 3.890767271 1.857020344 0.036156172
Cheese (ukb-b-1489) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 180 1.807159612 0.703598667 0.011035915
Other dessert (ukb-b-17441) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 10 -3.288862563 1.270537991 0.03218513
Cheesecake (ukb-b-1814) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 13 4.171903595 1.681427277 0.030510358
Espresso (ukb-b-19142) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 21 0.835461348 0.356225566 0.019010984
Espresso (ukb-b-19142) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Simple mode 21 3.359300499 0.862308206 0.000897729
Melon (ukb-b-19862) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted median 7 2.501082349 1.018348456 0.014048604
Melon (ukb-b-19862) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 7 2.114045176 0.81445494 0.009441042
White pasta (ukb-b-2512) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 4 -1.674200215 0.792625468 0.034667492
Other vegetables (ukb-b-3055) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 7 4.832476495 1.719866901 0.037557225
Milk chocolate (ukb-b-4569) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Simple mode 8 -3.358026659 1.059860626 0.015743642
Sausage (ukb-b-5847) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 5 -0.464751883 0.234937186 0.047906561
Spinach (ukb-b-812) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 7 -0.799882491 0.368818995 0.030100373

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Avocado (ukb-b-12236) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -0.91246459914425 0.332300569956938 0.0060344897406079
Naan bread (ukb-b-13281) Heel bone mineral density (BMD) T-score, automated (right) rs418458 -1.88602987557296 0.811135355876292 0.0200627215658512
Naan bread (ukb-b-13281) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -1.66928607956048 0.715469919707117 0.0196411953288149
Cottage cheese (ukb-b-14171) Heel bone mineral density (BMD) T-score, automated (right) rs80187236 -5.40352170220948 2.59921811161136 0.0376262891329622
Cottage cheese (ukb-b-14171) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger -5.2534118644838 1.98628725752165 0.0294909833701959
Mozzarella (ukb-b-14505) Heel bone mineral density (BMD) T-score, automated (right) rs148683239 16.4794996722023 7.9944911117295 0.0392690004335699
Mozzarella (ukb-b-14505) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 3.89076727123865 1.8570203435655 0.0361561722136492
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs113829457 14.5204590783925 7.24642682144114 0.0450904682532138
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs12447542 18.169296522109 7.50977333954506 0.0155452756754295
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs35760956 -7.40804980692513 3.25808130140675 0.0229812538215805
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs61734410 -4.63552299747808 2.33037108202234 0.0466815541314991
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs7012814 4.36593019048288 1.96909716408963 0.0266077640538557
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) rs72829857 -13.1489365192641 5.54174766838103 0.0176583255081613
Cheese (ukb-b-1489) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 1.80715961230277 0.70359866694056 0.0110359148524973
Other dessert (ukb-b-17441) Heel bone mineral density (BMD) T-score, automated (right) rs4923342 4.15783160611452 1.82423866885719 0.0226543051716332
Other dessert (ukb-b-17441) Heel bone mineral density (BMD) T-score, automated (right) rs76915123 -6.08858797618076 2.83807814666775 0.03192720949551
Other dessert (ukb-b-17441) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger -3.28886256253862 1.27053799122206 0.0321851303730094
Cheesecake (ukb-b-1814) Heel bone mineral density (BMD) T-score, automated (right) rs10179681 6.34927294531444 2.66697434068604 0.0172796526171852
Cheesecake (ukb-b-1814) Heel bone mineral density (BMD) T-score, automated (right) rs2392968 -14.4645438256089 6.73946706970817 0.0318534805741338
Cheesecake (ukb-b-1814) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 4.17190359487337 1.6814272767647 0.0305103582178823
Espresso (ukb-b-19142) Heel bone mineral density (BMD) T-score, automated (right) rs80138696 2.98619931994486 1.19130887298487 0.0121879903408662
Espresso (ukb-b-19142) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.835461348211197 0.356225565682997 0.0190109839050956
Melon (ukb-b-19862) Heel bone mineral density (BMD) T-score, automated (right) rs142872754 2.57332053834439 1.26111803377304 0.041299825942479
Melon (ukb-b-19862) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 2.11404517616256 0.814454939936356 0.0094410424959929
White pasta (ukb-b-2512) Heel bone mineral density (BMD) T-score, automated (right) rs10804975 -5.05155017877259 1.98547778811775 0.0109512939127093
White pasta (ukb-b-2512) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -1.674200215129 0.792625468161907 0.0346674920482499
Other vegetables (ukb-b-3055) Heel bone mineral density (BMD) T-score, automated (right) rs10867703 2.47752799987182 1.09375751069523 0.0235032981740281
Other vegetables (ukb-b-3055) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 4.83247649519328 1.71986690058855 0.037557225399053
Milk chocolate (ukb-b-4569) Heel bone mineral density (BMD) T-score, automated (right) rs78656169 -4.23210951902251 1.98504693714262 0.0330072835139061
Sausage (ukb-b-5847) Heel bone mineral density (BMD) T-score, automated (right) rs76866342 -1.24758804554359 0.524296298478443 0.0173338999413606
Sausage (ukb-b-5847) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -0.464751882925882 0.234937185999998 0.0479065607724235
Spinach (ukb-b-812) Heel bone mineral density (BMD) T-score, automated (right) rs111686396 -0.971956247657341 0.442975431901046 0.0282243513220429
Spinach (ukb-b-812) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -0.799882490832183 0.368818995404466 0.0301003727239058