ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other fish (ukb-b-1252) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 13 -1.382860088 0.604686713 0.022201463
Double crust pastry (ukb-b-1255) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 8 3.955668229 1.549500847 0.043322976
Celery (ukb-b-14145) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted median 11 0.990353686 0.405542981 0.014604378
Celery (ukb-b-14145) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 11 0.986786524 0.276616547 0.000360617
Grapefruit juice (ukb-b-14351) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 14 3.186837114 1.249533105 0.025445935
Broad bean (ukb-b-15212) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 13 1.468595372 0.599894043 0.03235514
Side salad (ukb-b-1604) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 12 0.254319809 0.122106138 0.03727159
Other dessert (ukb-b-17441) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 13 0.672531178 0.341552881 0.048948534
Leek (ukb-b-2530) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 10 1.04030616 0.491646341 0.034347835
Spirits (ukb-b-3751) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 15 -0.792476338 0.362226541 0.047551087
Fresh fruit (ukb-b-3881) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 136 -0.742862718 0.248854135 0.002834549
Drinking water (ukb-b-3975) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 18 0.155575618 0.068584158 0.023305446
Mushroom (ukb-b-4043) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 7 -0.638677078 0.323780156 0.048545259
Liver (ukb-b-6373) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Simple mode 12 -2.615556057 1.051801706 0.03020994
Fresh tomato (ukb-b-730) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted median 9 0.628477826 0.258671915 0.015114118
Fresh tomato (ukb-b-730) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 9 0.535513889 0.187442662 0.004277363
Poultry (ukb-b-8006) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Weighted median 73 -0.755016136 0.378767411 0.046223101
Cappuccino (ukb-b-8374) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) MR Egger 19 1.576913798 0.728723996 0.044997928
Other milk-based pudding (ukb-b-9857) (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) Inverse variance weighted 14 1.397536306 0.555316807 0.011847751

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other fish (ukb-b-1252) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -1.38286008847694 0.604686712970613 0.0222014632276193
Double crust pastry (ukb-b-1255) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 3.95566822863086 1.54950084748997 0.0433229764880926
Celery (ukb-b-14145) Heel bone mineral density (BMD) T-score, automated (right) rs2173148 2.46658143811959 1.09339254474499 0.0240770551534949
Celery (ukb-b-14145) Heel bone mineral density (BMD) T-score, automated (right) rs79810016 1.69233292746784 0.653117488596862 0.0095652575666418
Celery (ukb-b-14145) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.986786524270142 0.276616547056389 0.0003606172148197
Grapefruit juice (ukb-b-14351) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 3.18683711404818 1.24953310480274 0.0254459351503667
Broad bean (ukb-b-15212) Heel bone mineral density (BMD) T-score, automated (right) rs138763370 4.40774607178517 2.20058857533239 0.0451788905239585
Broad bean (ukb-b-15212) Heel bone mineral density (BMD) T-score, automated (right) rs72662025 -3.74330751799188 1.82483751276241 0.0402367630063539
Broad bean (ukb-b-15212) Heel bone mineral density (BMD) T-score, automated (right) rs77934214 2.16315881442026 0.89077152664381 0.0151651729497096
Broad bean (ukb-b-15212) Heel bone mineral density (BMD) T-score, automated (right) rs7844716 -5.35966615708796 1.9485187786638 0.0059479671666099
Broad bean (ukb-b-15212) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 1.46859537200238 0.59989404302564 0.0323551396950008
Side salad (ukb-b-1604) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.254319808908559 0.12210613810936 0.0372715901731473
Other dessert (ukb-b-17441) Heel bone mineral density (BMD) T-score, automated (right) rs72763755 3.07495166174164 1.39588121557039 0.0276035687602754
Other dessert (ukb-b-17441) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.672531178040825 0.341552881464086 0.0489485341211973
Leek (ukb-b-2530) Heel bone mineral density (BMD) T-score, automated (right) rs73181706 2.84065213205629 1.42972923355229 0.0469394401964959
Leek (ukb-b-2530) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 1.04030616003195 0.49164634132322 0.0343478346937741
Spirits (ukb-b-3751) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger -0.792476338175854 0.362226540638576 0.0475510868061788
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs10875917 -6.97981167332283 3.1776379557862 0.0280532524569756
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs1375566 -5.09585361930706 2.45346459326357 0.0378012710971345
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs4585695 -10.3179792527464 2.93231560186667 0.0004336443121777
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs4708180 7.11983391210559 3.04712681658635 0.0194614034590229
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs5749227 -7.60443872745347 3.31756522283654 0.0218955701975537
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs60452247 -6.70164084173914 2.68893771275922 0.0126918603134664
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs6758494 -9.00043105728335 2.92848838452561 0.0021163100599504
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) rs67667422 7.929185553639 3.6052388784147 0.0278529774577099
Fresh fruit (ukb-b-3881) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -0.74286271830619 0.248854134642043 0.0028345494165258
Drinking water (ukb-b-3975) Heel bone mineral density (BMD) T-score, automated (right) rs113928962 0.709608534200108 0.339843590058551 0.036793822015024
Drinking water (ukb-b-3975) Heel bone mineral density (BMD) T-score, automated (right) rs28444545 -0.786121093743019 0.399583261106931 0.0491425961979819
Drinking water (ukb-b-3975) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.155575617678691 0.068584157664098 0.0233054464883741
Mushroom (ukb-b-4043) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted -0.638677077804909 0.323780156490034 0.0485452589299723
Fresh tomato (ukb-b-730) Heel bone mineral density (BMD) T-score, automated (right) rs12607299 1.12653647127319 0.511697007112061 0.0276957396522912
Fresh tomato (ukb-b-730) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 0.535513888716575 0.18744266238465 0.0042773627103947
Poultry (ukb-b-8006) Heel bone mineral density (BMD) T-score, automated (right) rs12928131 4.43992101394435 2.00509755821742 0.0268070004194635
Poultry (ukb-b-8006) Heel bone mineral density (BMD) T-score, automated (right) rs1959437 -6.35780105536741 2.09006064424667 0.0023507294934712
Poultry (ukb-b-8006) Heel bone mineral density (BMD) T-score, automated (right) rs2965200 -5.13834371431039 1.85705922435387 0.0056587760736389
Cappuccino (ukb-b-8374) Heel bone mineral density (BMD) T-score, automated (right) rs115241046 3.5712554336409 1.1722838977497 0.0023159308483735
Cappuccino (ukb-b-8374) Heel bone mineral density (BMD) T-score, automated (right) rs13084063 -3.98426052453942 1.40821108897633 0.0046649026887199
Cappuccino (ukb-b-8374) Heel bone mineral density (BMD) T-score, automated (right) rs62626322 -2.12327786100562 1.01305709430296 0.0360900557855939
Cappuccino (ukb-b-8374) Heel bone mineral density (BMD) T-score, automated (right) All - MR Egger 1.57691379830706 0.728723996055838 0.0449979280084719
Other milk-based pudding (ukb-b-9857) Heel bone mineral density (BMD) T-score, automated (right) All - Inverse variance weighted 1.3975363064441 0.555316806763815 0.0118477507347846