ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Pain in joint (ukb-e-745_AFR)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other alcohol (ukb-b-12901) (👉 📊) Pain in joint Inverse variance weighted 16 -4.977939254 2.132958081 0.019605173
Other sweets (ukb-b-139) (👉 📊) Pain in joint MR Egger 16 -3.93945609 1.834135636 0.049715271
Celery (ukb-b-14145) (👉 📊) Pain in joint Inverse variance weighted 8 -3.097551359 1.094430931 0.004650657
Vegetarian alternatives (ukb-b-14425) (👉 📊) Pain in joint Weighted median 6 -29.33457646 14.00340177 0.036187185
Cheese (ukb-b-1489) (👉 📊) Pain in joint MR Egger 179 -6.059914823 2.322353021 0.009846778
Low calorie hot chocolate (ukb-b-1795) (👉 📊) Pain in joint Inverse variance weighted 8 -7.790428019 2.794990539 0.005315213
Orange juice (ukb-b-2763) (👉 📊) Pain in joint Weighted median 7 -2.722601572 1.252900667 0.029777409
Orange juice (ukb-b-2763) (👉 📊) Pain in joint Inverse variance weighted 7 -2.047571328 0.953500075 0.031759343
Pork (ukb-b-5185) (👉 📊) Pain in joint Inverse variance weighted 9 3.454604681 1.749064807 0.048255064
Pulses (ukb-b-621) (👉 📊) Pain in joint Weighted median 6 -6.919337777 3.392569297 0.041394489
Pulses (ukb-b-621) (👉 📊) Pain in joint Inverse variance weighted 6 -7.043874963 2.572373832 0.006176182
Soft cheese (ukb-b-8007) (👉 📊) Pain in joint MR Egger 9 11.95952826 4.802293284 0.041573527

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other alcohol (ukb-b-12901) Pain in joint rs309494 44.2128511092204 17.4344849098406 0.0112145148675987
Other alcohol (ukb-b-12901) Pain in joint rs358054 -34.3725201869228 15.1739673311736 0.0234985926430183
Other alcohol (ukb-b-12901) Pain in joint rs878282 -6.71580257745337 2.60685223167222 0.0099889538505678
Other alcohol (ukb-b-12901) Pain in joint All - Inverse variance weighted -4.97793925376538 2.13295808094853 0.0196051730437225
Other sweets (ukb-b-139) Pain in joint rs4849108 21.5912251817437 7.87117436117188 0.0060866697697391
Other sweets (ukb-b-139) Pain in joint All - MR Egger -3.93945608994855 1.83413563566843 0.0497152707313266
Celery (ukb-b-14145) Pain in joint All - Inverse variance weighted -3.09755135891321 1.09443093147432 0.0046506568499058
Vegetarian alternatives (ukb-b-14425) Pain in joint rs9993067 -47.3806935016828 18.5860654741553 0.0107952114538683
Cheese (ukb-b-1489) Pain in joint rs11213287 21.9930904298892 10.8362716814474 0.0423991542685198
Cheese (ukb-b-1489) Pain in joint rs113367286 -37.991528159318 19.045172170728 0.0460634443897045
Cheese (ukb-b-1489) Pain in joint rs12670420 43.6200570729719 20.6260679497966 0.034446796091578
Cheese (ukb-b-1489) Pain in joint rs3733421 30.6023629672671 10.966307886703 0.005261364418669
Cheese (ukb-b-1489) Pain in joint rs62048491 22.8113999291008 9.10972060775439 0.0122772908867485
Cheese (ukb-b-1489) Pain in joint rs6498981 19.3288567552251 8.87015061223789 0.0293249808346788
Cheese (ukb-b-1489) Pain in joint rs683996 16.1445835538382 7.34371941627217 0.0279191517963557
Cheese (ukb-b-1489) Pain in joint All - MR Egger -6.05991482286817 2.32235302090138 0.0098467782148071
Low calorie hot chocolate (ukb-b-1795) Pain in joint rs116707297 -23.9278090432758 11.6501714211786 0.0399893437327183
Low calorie hot chocolate (ukb-b-1795) Pain in joint All - Inverse variance weighted -7.79042801852684 2.79499053860063 0.0053152132568131
Orange juice (ukb-b-2763) Pain in joint rs79774500 -3.42592457113235 1.67533773261902 0.0408631616304291
Orange juice (ukb-b-2763) Pain in joint All - Inverse variance weighted -2.04757132811493 0.953500074630871 0.0317593428148463
Pork (ukb-b-5185) Pain in joint All - Inverse variance weighted 3.4546046807446 1.74906480731299 0.0482550636895943
Pulses (ukb-b-621) Pain in joint rs1104785 -11.7046911048449 5.40374263009485 0.0303085770171313
Pulses (ukb-b-621) Pain in joint All - Inverse variance weighted -7.04387496289258 2.5723738321827 0.006176182183081
Soft cheese (ukb-b-8007) Pain in joint All - MR Egger 11.9595282588675 4.80229328367281 0.0415735271896175