ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_AFR)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sweets (ukb-b-10217) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted median 12 -2.948035293 1.309086167 0.024323564
Grape (ukb-b-12051) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted median 4 -7.304528481 2.886492242 0.011387086
Grape (ukb-b-12051) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 4 -6.463207608 2.250907689 0.00408686
Flavoured milk (ukb-b-12763) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted median 6 -9.12116533 4.140398637 0.027597011
Flavoured milk (ukb-b-12763) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 6 -7.872833081 3.055169412 0.00996939
Lamb/mutton (ukb-b-14179) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted mode 111 -6.141268144 2.991219106 0.042435328
Broad bean (ukb-b-15212) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 10 3.127111849 1.448404447 0.030849811
Unsalted peanuts (ukb-b-15555) (👉 📊) M17 Gonarthrosis [arthrosis of knee] MR Egger 15 9.135026932 3.804563912 0.032020771
Ice-cream (ukb-b-17189) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 10 4.017899068 1.467447751 0.00618106
Butternut squash (ukb-b-20341) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted median 7 6.627469164 2.903838685 0.02247086
Green tea (ukb-b-4078) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 25 -0.033543443 0.014130113 0.017601421
Feta (ukb-b-4740) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 14 4.042948594 1.653439756 0.01447821
Feta (ukb-b-4740) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Simple mode 14 7.594744703 3.372672675 0.042263002
Scone (ukb-b-5627) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Weighted median 3 9.750186019 4.878630239 0.045657075
Scone (ukb-b-5627) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 3 9.923281977 4.064066902 0.014617792
Breaded fish (ukb-b-5753) (👉 📊) M17 Gonarthrosis [arthrosis of knee] Inverse variance weighted 13 2.140959414 1.092203118 0.049969973

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sweets (ukb-b-10217) M17 Gonarthrosis [arthrosis of knee] rs72859681 -4.48853364958965 1.81188514295362 0.0132390695402817
Sweets (ukb-b-10217) M17 Gonarthrosis [arthrosis of knee] rs79312248 6.82583534827033 3.31160376887728 0.0392851828121091
Grape (ukb-b-12051) M17 Gonarthrosis [arthrosis of knee] rs10497191 -9.6777111158009 4.21176399650276 0.0215742590099806
Grape (ukb-b-12051) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted -6.46320760842736 2.2509076890959 0.0040868604800264
Flavoured milk (ukb-b-12763) M17 Gonarthrosis [arthrosis of knee] rs79169291 -13.1964200759281 4.93947782662976 0.0075485515798993
Flavoured milk (ukb-b-12763) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted -7.87283308102191 3.05516941221293 0.0099693899734501
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs10883567 44.1382399168382 17.5695906465084 0.011998272821883
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs11673714 106.11507811594 32.356400868139 0.0010396545433462
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs11756299 27.2592616083097 9.77131554015753 0.0052753188450195
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs1711171 -22.8448481516235 9.97175917826706 0.0219660361495068
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs1958801 -24.6983701759074 10.3746571689563 0.0172823829794452
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs4272399 34.5476401462405 16.0133126891437 0.0309719864756562
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs429358 -9.7710561313652 4.80749150940286 0.0421066477238731
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs4676964 56.99877730923 23.6550079429806 0.0159706291149399
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs62176228 -82.3958978086439 33.9464284700257 0.0152144732310331
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs6581296 17.8444894659627 8.8234413517101 0.0431354934247665
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs74697766 -47.1118608140082 21.3839482306929 0.0275847867484095
Lamb/mutton (ukb-b-14179) M17 Gonarthrosis [arthrosis of knee] rs8107139 32.583264765857 15.2255571852753 0.0323517287045923
Broad bean (ukb-b-15212) M17 Gonarthrosis [arthrosis of knee] rs60801456 39.1503100342471 18.5266207021408 0.0345843221475655
Broad bean (ukb-b-15212) M17 Gonarthrosis [arthrosis of knee] rs77934214 3.66150280286734 1.60599980316661 0.0226142165683929
Broad bean (ukb-b-15212) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted 3.127111848888 1.4484044468558 0.0308498108416063
Unsalted peanuts (ukb-b-15555) M17 Gonarthrosis [arthrosis of knee] All - MR Egger 9.13502693172934 3.80456391216174 0.0320207707301874
Ice-cream (ukb-b-17189) M17 Gonarthrosis [arthrosis of knee] rs496092 8.98413533175563 4.05580920963514 0.0267513005495827
Ice-cream (ukb-b-17189) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted 4.01789906827868 1.46744775071031 0.0061810601441562
Butternut squash (ukb-b-20341) M17 Gonarthrosis [arthrosis of knee] rs4817646 -28.217885665945 12.40984758327 0.022976200369795
Butternut squash (ukb-b-20341) M17 Gonarthrosis [arthrosis of knee] rs74413219 9.85990627002682 4.33205758414395 0.0228440311081356
Green tea (ukb-b-4078) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted -0.0335434433095912 0.0141301125187422 0.0176014206367374
Feta (ukb-b-4740) M17 Gonarthrosis [arthrosis of knee] rs4704539 8.7783931103875 3.73398616690039 0.0187258419407041
Feta (ukb-b-4740) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted 4.04294859442969 1.65343975552946 0.014478210440632
Scone (ukb-b-5627) M17 Gonarthrosis [arthrosis of knee] rs79778360 9.77064760545787 4.90532740337705 0.0463881623473341
Scone (ukb-b-5627) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted 9.92328197713121 4.06406690246127 0.0146177923445026
Breaded fish (ukb-b-5753) M17 Gonarthrosis [arthrosis of knee] All - Inverse variance weighted 2.14095941400019 1.09220311753067 0.0499699728282253