ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

M51 Other intervertebral disk disorders (ukb-e-M51_CSA)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Satsuma (ukb-b-11563) (👉 📊) M51 Other intervertebral disk disorders MR Egger 13 3.697928067 1.559261006 0.037047641
Pineapple (ukb-b-1164) (👉 📊) M51 Other intervertebral disk disorders MR Egger 16 -9.751099721 4.526441447 0.049126205
Shellfish (ukb-b-143) (👉 📊) M51 Other intervertebral disk disorders Weighted median 19 13.61268151 5.151961219 0.00823614
Shellfish (ukb-b-143) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 19 10.32827267 3.556611754 0.003684705
Grapefruit juice (ukb-b-14351) (👉 📊) M51 Other intervertebral disk disorders MR Egger 14 -15.50914094 6.159311786 0.027008261
Cereal (ukb-b-15926) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 165 -1.960977276 0.787577849 0.012778489
Mixed fruit (ukb-b-18956) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 12 4.515930417 1.964436631 0.021513884
Parsnip (ukb-b-2468) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 11 5.596953088 1.956810615 0.00423317
Lettuce (ukb-b-2867) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 10 -2.561950143 1.182693043 0.030295877
Croissant (ukb-b-4007) (👉 📊) M51 Other intervertebral disk disorders MR Egger 18 -10.0530049 3.948705491 0.021581427
Croissant (ukb-b-4007) (👉 📊) M51 Other intervertebral disk disorders Weighted median 18 -8.469012232 3.083160108 0.006016863
Croissant (ukb-b-4007) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 18 -6.071582832 2.188498375 0.005531817
Croissant (ukb-b-4007) (👉 📊) M51 Other intervertebral disk disorders Simple mode 18 -9.379396211 4.32526816 0.044596991
Croissant (ukb-b-4007) (👉 📊) M51 Other intervertebral disk disorders Weighted mode 18 -9.018790291 3.543189578 0.020907297
Pork (ukb-b-5185) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 12 -3.181238637 1.55313445 0.040533555
Pork (ukb-b-5640) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 76 3.205996702 1.497266835 0.032255278
Chocolate sweet (ukb-b-9835) (👉 📊) M51 Other intervertebral disk disorders Inverse variance weighted 10 -3.6967033 1.752203966 0.034880339

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Satsuma (ukb-b-11563) M51 Other intervertebral disk disorders rs114628454 4.29173997556797 1.9153791190639 0.0250472067838765
Satsuma (ukb-b-11563) M51 Other intervertebral disk disorders All - MR Egger 3.69792806732556 1.55926100636909 0.0370476408702098
Pineapple (ukb-b-1164) M51 Other intervertebral disk disorders rs2454222 20.6982827248948 8.97778535956632 0.0211385956117385
Pineapple (ukb-b-1164) M51 Other intervertebral disk disorders All - MR Egger -9.75109972121811 4.52644144676764 0.0491262052832517
Shellfish (ukb-b-143) M51 Other intervertebral disk disorders rs2272317 19.029072673066 7.43791683181967 0.0105158871028759
Shellfish (ukb-b-143) M51 Other intervertebral disk disorders All - Inverse variance weighted 10.328272667192 3.55661175351742 0.0036847046857244
Grapefruit juice (ukb-b-14351) M51 Other intervertebral disk disorders rs11074030 23.5429246962257 11.9225938190587 0.0483081206440467
Grapefruit juice (ukb-b-14351) M51 Other intervertebral disk disorders All - MR Egger -15.5091409415171 6.15931178587466 0.0270082607604076
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs11113399 -22.3841387856258 10.2007434944238 0.0282092906240278
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs13066686 -31.5836054816529 11.3245615366562 0.0052879666673319
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs1604918 23.8981455126661 11.210124143367 0.033020336157585
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs1966434 -25.8417041556254 10.3223023356135 0.0122977731686838
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs2456141 -30.672119487909 10.8063655761024 0.0045349114013811
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs2903760 -22.796368571098 11.2035683102073 0.0418768615076803
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs2927238 -22.4076513931586 9.68135460889084 0.0206394275591069
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs78959390 -17.3578695865441 8.10930552698619 0.0323153653112722
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders rs9846396 -20.1380416798971 8.77383558667714 0.0217194831094244
Cereal (ukb-b-15926) M51 Other intervertebral disk disorders All - Inverse variance weighted -1.96097727617391 0.787577848545648 0.0127784889151731
Mixed fruit (ukb-b-18956) M51 Other intervertebral disk disorders rs79042385 12.5462923090173 5.94909999138748 0.0349497990822491
Mixed fruit (ukb-b-18956) M51 Other intervertebral disk disorders All - Inverse variance weighted 4.51593041735266 1.96443663140749 0.021513884474944
Parsnip (ukb-b-2468) M51 Other intervertebral disk disorders rs9398444 13.9587841578179 7.02657138543606 0.0469699384052999
Parsnip (ukb-b-2468) M51 Other intervertebral disk disorders All - Inverse variance weighted 5.59695308812933 1.95681061453919 0.004233170340428
Lettuce (ukb-b-2867) M51 Other intervertebral disk disorders rs4274598 -6.48214866812329 3.15536237273953 0.0399439750055694
Lettuce (ukb-b-2867) M51 Other intervertebral disk disorders All - Inverse variance weighted -2.56195014283423 1.18269304263609 0.0302958765383637
Croissant (ukb-b-4007) M51 Other intervertebral disk disorders All - Inverse variance weighted -6.07158283167664 2.18849837453715 0.0055318167172702
Croissant (ukb-b-4007) M51 Other intervertebral disk disorders All - MR Egger -10.0530048965398 3.94870549059048 0.0215814270385897
Pork (ukb-b-5185) M51 Other intervertebral disk disorders All - Inverse variance weighted -3.18123863704153 1.55313445041351 0.0405335548431605
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs17446175 31.9179959756204 14.5446327024584 0.0282004738500045
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs2387807 17.0306140036859 7.07343913660289 0.0160540217562292
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs254152 20.3901559472887 9.85939807799283 0.0386312426000105
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs4605770 26.8210623032334 12.9605858746909 0.0385054855509048
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs61791721 31.5163499978609 13.191232465168 0.0168856045661619
Pork (ukb-b-5640) M51 Other intervertebral disk disorders rs9696811 35.5085657094792 14.187455414657 0.0123210186795254
Pork (ukb-b-5640) M51 Other intervertebral disk disorders All - Inverse variance weighted 3.20599670198343 1.49726683533512 0.0322552776171702
Chocolate sweet (ukb-b-9835) M51 Other intervertebral disk disorders All - Inverse variance weighted -3.69670330041812 1.75220396562846 0.034880338712561